8,410 research outputs found
Experimental data associated with the study "The Ixodes scapularis symbiont Rickettsia buchneri inhibits growth of pathogenic Rickettsiaceae in tick cells: implications for vector competence"
No full textSpreadsheets containing raw data from fluorescent plate reader experiments detailed in the research paper.These experimental data are made available as part of the study "The Ixodes scapularis symbiont Rickettsia buchneri inhibits growth of pathogenic Rickettsiaceae in tick cells: implications for vector competence" published in Frontiers in Veterinary Science.
Abstract: The blacklegged tick Ixodes scapularis is a vector of pathogens of medical and veterinary importance in North America. Unlike other important human-biting Ixodes species however, this tick does not transmit pathogenic Rickettsia species, instead hosting a rickettsial endosymbiont, Rickettsia buchneri. A gene cluster encoding aminoglycoside antibiotic biosynthesis machinery has been identified in R. buchneri, which is not present in other rickettsiae, and therefore antibiotic production might represent a mechanism by which the endosymbiont is able to exclude pathogenic Rickettsia species from I. scapularis. This study identifies a second antibiotic cluster in R. buchneri with genes similar to polyketide/non-ribosomal peptide synthesis genes. Using cell culture experiments we provide evidence that infection of tick cells with R. buchneri, even at low rates, significantly reduces the ability of the pathogens Anaplasma phagocytophilum and R. parkeri to infect and replicate in cells, whereas the presence of low-pathogenic R. amblyommatis or the endosymbiotic R. peacockii in cells only partially reduced infection by R. parkeri. This research suggests a potential role of the endosymbiont in preventing other rickettsiae from colonizing I. scapularis and/or being transmitted transovarially. Whilst a link between the observed inhibition and antibiotic production is yet to be confirmed, this work contributes further to our understanding of rickettsial competition and how endosymbionts might alter vector competence by preventing colonization of the tick by pathogens.National Institutes of Health (grants R01 AI49424 and R01 AI081690 to UGM)University of Minnesota Agricultural Experiment StationCull, Benjamin; Burkhardt, Nicole Y; Wang, XinRu; Thorpe, Cody J; Oliver, Jonathan D; Kurtti, Timothy J; Munderloh, Ulrike G. (2021). Experimental data associated with the study "The Ixodes scapularis symbiont Rickettsia buchneri inhibits growth of pathogenic Rickettsiaceae in tick cells: implications for vector competence". Retrieved from the University Digital Conservancy, https://doi.org/10.13020/ZQXG-JF78
J.C. Painter letter to Benjamin Lundy
No full textLetter from J.E. Painter to (presumably) Benjamin Lundy, answering a request for information about the history and operations of the Underground Railroad. Letter includes details of a story of an ex-slave transported on the Underground Railroad through Ohio and stories of the plight of other fugitive slaves crossing the Ohio River.
Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His "Genius of Universal Emancipation" was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
Mexican land grant contract to Benjamin Lundy, March 10, 1835 (English)
No full textLegal document from an unsigned officer to Benjamin Lundy, authorizing him rights as empresario to a tract of land in then-Mexico. The document extends a previous treaty made to Lundy by the government of Mexico from November 17, 1823 -- presumably, this land is to be the site of Lundy's freed slave colony. Original Spanish-language document is also a part of this collection. Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His Genius of Universal Emancipation was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
Eli Nichols letter to Benjamin Lundy, March 17th, 1839
No full textFriendly note from Eli Nichols to Benjamin Lundy covering topics in contemporary abolition, ranging from the social status of abolitionists to the oppression of the poor. Much of the letter concerns a review of contemporary social movements in equality-based education, including Shaker and Quaker communities. The letter concludes in discussion of Nichols' and Lundy's interest in forming a freed slave colony or community in then-Mexico, and describes the climate and culture of those regions in detail. Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His Genius of Universal Emancipation was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
Mexican land grant contract to Benjamin Lundy, March 10, 1835 (Spanish)
No full textLegal document in Spanish from the government of Tamaulipas, Mexico, to Benjamin Lundy, which appears to grant Lundy the rights of empresario for his proposed colony for freed slaves in Tamaulipas. This document appears to be truncated; it ends abruptly after 2 pages. Collection also includes a period translation of this contract with Lundy in English, which appears to contain the full text of the agreement. Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His Genius of Universal Emancipation was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
General Benjamin Butler Letter Regarding the naming of Newport News, Virginia
No full textDigital images of an original letter written by Former Union Major-General Benjamin Butler in reply to a query by author, Edwin Everett Hale on how Newport News, Virginia had received it's name. both sides of the original letter are included along with a typed transcription of the letter
Cinq années de voyage en Orient 1846-1851 par Israel-Joseph Benjamin II, voyageur et auteur, demeurant à Faltischan (Moldavie). Paris en vente chez Michel Levy Frères, rue Vivienne, 2 bis 1856 L' auteur se réserve le droit de traduction et de reproduction
No full textPreface: by Benjamin, J.Dedication: by the author to M.J. Altaras aîné de Marseille et M. Albert Cohn.Content description: Detailed contentsPagination: PP28+240PVolumes: 1Text Genre:Pros
The description and use of an orrery of a new construction : representing in the various parts of its machinery all the motions and phoenomena [i.e phenomena] of the planetary system ...
No full textby Benjamin Marti
The description and use of an universal sliding rule : which ... is adapted to answer all questions in arithmetic, mixt-mathematics, and philosophy, in the most easy and expeditious manner, as shewn in sixty examples of principal utility in the practical parts of science
No full textby Benjamin MartinErscheinungsdatum nach EST
R. Williams letter to Mrs. Susan M.Weirman, July 21, 1896
No full textResponse letter from R. Williams to Susan M. Wierman [sometimes spelled Weirman] following up on a visit from photographer M. Wooley, presumably to snap photographs of Susan and the Lundy home to accompany Williams' biographical essay on Lundy. Williams sends along Wooley's letters and requests additional information from Ms. Wierman about the life and times of some meeting houses significant in the life and times of her father, anti-slavery activist and abolitionist periodical publisher Benjamin Lundy. Benjamin Lundy (1789-1839) was a prominent Quaker abolitionist best known for his development of abolitionist periodicals. His Genius of Universal Emancipation was first published in 1821 from his home in Mt. Pleasant, Ohio, and enjoyed a wide circulation across the antebellum United States. In the 1820s, the young William Lloyd Garrison came to work for The Genius. Benjamin Lundy traveled widely seeking subscriptions to The Genius, giving talks about the anti-slavery movement, and observing and documenting the conditions of enslaved people across the Americas. He was also involved in the establishment of freed slave colonies in Mexico
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