6,680 research outputs found
Table1_Bu-Fei-Huo-Xue capsule alleviates bleomycin-induced pulmonary fibrosis in mice through modulating gut microbiota.DOCX
Introduction: Bu-Fei-Huo-Xue capsule (BFHX) has been used to treat pulmonary fibrosis (PF) in clinic. However, the mechanism of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis remains unclear. Recent studies have shown that the changes in gut microbiota were closely related to the progression of pulmonary fibrosis. Modulating gut microbiota provides new thoughts in the treatment of pulmonary fibrosis.Methods: In this study,a mouse model of pulmonary fibrosis was induced using bleomycin (BLM) and treated with Bu-Fei-Huo-Xue capsule. We firstly evaluated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis model mice. Besides,the anti-inflammatory and anti- oxidative effects of Bu-Fei-Huo-Xue capsule were evaluated. Furthermore, 16S rRNA sequencing was used to observe the changes in gut microbiota in pulmonary fibrosis model mice after Bu-Fei-Huo-Xue capsule treatment.Results: Our results showed that Bu-Fei-Huo-Xue capsule significantly reduced the collagen deposition in pulmonary fibrosis model mice. Bu-Fei-Huo-Xue capsule treatment also reduced the levels and mRNA expression of pro-inflammatory cytokines and inhibited the oxidative stress in lung. 16S rRNA sequencing showed that Bu-Fei-Huo-Xue capsule affected the diversity of gut microbiota and the relative abundances of gut microbiota such as Lactobacillus, Lachnospiraceae_NK4A136_group, and Romboutsia.Conclusion: Our study demonstrated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis. The mechanisms of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis may be associated with regulating gut microbiota.</p
Fei-yen wai-zhuan the true era of its birth and investigation of its author
Fei-yen wai-zhuan 飛燕外傳 (The Unofficial Biography of [Zhao] Fei-yen) is one of the classical-language fictions in traditional China, describing the famous romance between Emperor Cheng-di 成帝 and Zhao Fei-yen 趙飛燕 sisters in the Former Han Dynasty. The author is attributed with Ling Xüan 伶玄, who definitely had confessed that he was living with the Former Han Dynasty in his brief autobiography. However, it was too suspicious to believe, from the beginning of its appearance in the Southern Song Dynasty, scholars have been puzzled to determine the true era of its birth. Through their discussions, now it is widely accepted that Fei-yen wai-zhuan was born during the Six Dynasties, not in the Tang Dynasty, though it is still lacking in conclusive evidence. But some insist that it could be compared with the great masterpieces of Tang-tales, like Ying-ying zhuan 鶯鶯傳, Li Wa zhuan 李娃傳, Huo Xiao-yü zhuan 霍小玉傳, which belonged to the Tang Dynasty. Then should we say that Fei-yen wai-zhuan was a premature masterpiece? It still remains a great mystery to all, including its author Ling Xüan himself. This study, paying attention to the text itself, proves this tale should belong to the Tang Dynasty. Its main keywords are two, Zhen-la 眞臘 and Qi-chu Ling-hua jing 七出菱花鏡 (Water-chestnut flower shaped bronze mirror, circled by seven petals). The former, used first in the historical records in China was in the Sui Dynasty Da-ye 大業 12years(616), and the latter one likely appeared after reign of Empress Wu(690--705). These facts simply tell us Fei-yen wai-zhuan was born in the Tang Dynasty. The true author of this tale is Niu Seng-ru 牛僧孺, a famous prime minister of late Tang and was also a well-known writer of Tang-tales, who authored Xüan-guai lu 玄怪錄. We could know the close affinities between Fei-yen wai-zhuan and Xüan-guai lu. As a drafted scholar-official, all of Niu's life had been under the strife in bureaucracy with the factional parties at that time. Once the opposition party blamed Niu for violating his majesty, to write the tale Zhou Qin xing-ji 周秦行記 named Niu Seng-ru. Though its writer was anonymous, Niu was nearly accused of injury to the majesy (Lèse majesté). I contend Niu decided to write Fei-yen wai-zhuan under a pseudonym to make counterattack against a recreant writer in the same manner and to regain true pride for himself
Supplementary Table 1 -Supplemental material for Increased expression of Ca<sub>V</sub>3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury
Supplemental material, Supplementary Table 1 for Increased expression of CaV3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury by Xue-Jing Kang, Ye-Nan Chi, Wen Chen, Feng-Yu Liu, Shuang Cui, Fei-Fei Liao, Jie Cai and You Wan in Molecular Pain</p
Figure -Supplemental material for Increased expression of Ca<sub>V</sub>3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury
Supplemental material, Figure for Increased expression of CaV3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury by Xue-Jing Kang, Ye-Nan Chi, Wen Chen, Feng-Yu Liu, Shuang Cui, Fei-Fei Liao, Jie Cai and You Wan in Molecular Pain</p
Supplementary Table 2 -Supplemental material for Increased expression of Ca<sub>V</sub>3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury
Supplemental material, Supplementary Table 2 for Increased expression of CaV3.2 T-type calcium channels in damaged DRG neurons contributes to neuropathic pain in rats with spared nerve injury by Xue-Jing Kang, Ye-Nan Chi, Wen Chen, Feng-Yu Liu, Shuang Cui, Fei-Fei Liao, Jie Cai and You Wan in Molecular Pain</p
Anthropology as an interdisciplinary field
The article discusses anthropology as an interdisciplinary field from the author's own research experience.AnthropologySociologySSCI0ARTICLE120-243
Wo zhe yi nian
by Fey Shiaw tong.Live recording.Prof. Rulan Chao Pian read "During my past year" by Fei Xiaotong.Electronic reproduction from Rulan Chao Pian Audio Cassette Collection.Read in Chinese.by Fey Shiaw tong
sj-pdf-1-jcb-10.1177_0271678X20918467 - Supplemental material for Brain deep medullary veins on 3-T MRI in a population-based cohort
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X20918467 for Brain deep medullary veins on 3-T MRI in a population-based cohort by Dong-Hui Ao, Ding-Ding Zhang, Fei-Fei Zhai, Jiang-Tao Zhang, Fei Han, Ming-Li Li, Jun Ni, Ming Yao, Shu-Yang Zhang, Li-Ying Cui, Zheng-Yu Jin, Li-Xin Zhou Yi-Cheng Zhu in Journal of Cerebral Blood Flow & Metabolism</p
[[alternative]]The Fine Artist's Self-Marketing---A Case of Chen Yi-Fei
[[abstract]]Abstract:
Must become artist this line of business, in the former idea should be one kind “Devotee” profession, but in the real life, as if majority people didn’t dare to the “Artist” profession, the reason that an artist most basic is facing many “Survival” the question, because also in the middle of this has too many “Contradictions”. “Economy” and “Artist” between if can a closer union, whether the artist can survive in the nowadays practical life? As the enterprise body management profession has the condition which survives in the society.
This research that one is good at the self-marketing take Chen Yi-Fei as an example. How discusses with fine artist to light, in the fit space position, own art idea in the suitable time makes the pinpointing, only then can develop the biggest benefit .Have left behind business and art will a “very perfect” fuse in together life way.
“Chen Yi-Fei Phenomenon” may inquire into an artist can develop by own limited condition belongs to its individual brand of infinite commercial art, and carries forward incisively the self-marketing idea.
Chen Yi-Fei make art business dealing and the creativity self-marketing for its goal and the strategy principle, own management and design and establishment “Yi-Fei” group, to show the self-marketing hope and the pursue, unfolds an artist's business ambition and the intense social sense of responsibility.
Generally specifically, this research Chen Yi-Fei succeeds the conclusion to have the following three essentials:.
(1)Grasps the artist own superiority condition effectively.Manipulation variation superiority strategy.
(2)Effective grasping trend of the times and market demand.Manipulation approval、demand strategy、sponsor strategy、platform strategy.
(3)Effectively grasps an artist self-marketing essence. Manipulation modernized tool、celebrity effect strategy、social person strategy.
Chen Yi-Fei's entire wrap artist self-marketing process, enables him to become widely known, nobody did not know and is known to everybody the flagship artist, his value has led art into general common populace, his fervor advanced boldly a development art business zealously with the process, he satisfied an artist also to satisfy an artist to the beautiful request for the wealth pursuance; He became the artist's paragon and raised the general populations to the happy thing fervor, and also relying on individual strength, let the artistic industry start out a living way, he is neither non-artist not entrepreneur, motion activist …and so on can describe that, In fact he attempts to unfold an artist “Hero” special characteristic and “Superhuman” the style.
Growth and Characterisation of Boron Rich Nanomaterials
In this study nanomaterials are grown in a solid state reaction at 1300C of boron, barium oxide and iron(II/III)oxide powders in an argon atmosphere. The nanomaterials are shown to be grown via vapour based method by growing the nanomaterials on a separate silicon wafer that has been sputtered with iron and placed downstream of the powders in the flow of argon. An area of the silicon wafer is kept free of iron by using a mask when sputtering the wafer. When nanomaterials are grown, the masked area remains free of nanomaterials. This shows that the presence of iron is vital for the nucleation of the nanomaterials and also indicates the possibility of growing these nanomaterials on targeted sites.
The nanomaterials produced are examined and it is found that we have a presence of amorphous, crystalline and multiple twinned nanowires. The evidence collected suggests that 70% of the nanowires are twinned. The single crystal nanowires can be identified as boron carbide by comparing to diffraction pattern simulations of a boron carbide unit cell. The twinned diffraction pattern is shown to be due to different segments of the nanowire being in different diffraction condition by using Dark Field imaging. The Twinned wires are also shown to have at least four segments in a cyclic [001] twinning orientation in simultaneous diffraction condition by comparing to a twinned structure constructed from simulations. Elemental analysis using Electron Energy Loss Spectroscopy and Energy Dispersive X-ray shows that the composition of the nanomaterials is mainly boron and carbon.
The role of the iron layer on the wafer is investigated to see how varying the thickness will affect the nanomaterials grown. It is successfully shown that an increase in the thickness of the iron layer results in a greater density of nanomaterials. However there is no great variation in the average diameter of the nanomaterials produced.
The absence of a visible signal for iron in the Elemental analysis of nanostructure covered silicon wafer shows that the amount of iron in the sample has decreased during the reaction. However iron is found in small amounts in droplet structures at the tips of nanomaterials this is different to work done on a similar system at 1100C. This suggests that the role of the iron in the growth of these nanomaterials at this temperature is not yet understood. However this work has confirmed that the iron is essential for the nucleation of the nanomaterials, but post nucleation growth that was previously assumed to be a conventional VLS growth may switch to an oxide assisted growth mode
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