137 research outputs found

    High altitude pulmonary edema at 2640 m altitude associated with an acute Rhinovirus infection. First case in the literature

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    High altitude pulmonary edema (HAPE) is a multifactorial condition that may occur after ascent of high altitudes, especially in genetic predisposed individuals. Diagnosis is challenging and could lead to potentially lethal complications such as acute respiratory distress syndrome (ARDS). We present one of the few reported cases of HAPE below 3000 m of altitude, and the first to our knowledge to present with a concomitant acute Rhinovirus infection, precipitating and complicating the diagnosis and clinical course. Clinical manifestations, treatment, and outcomes are shown below. © 2022 The Author

    Enhancing the contribution of land reform to Mexican agricultural development

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    The purpose of this paper is to consider whether the institutional factors associated with the Mexican land reform ( ejido ) sector constrain agricultural growth. Parting from the assumption that the ejido may be considered a more or less fixed element of Mexico's cultural and political scene, the paper focuses on the piecemeal changes that could help to enhance growth and productivity within the existing structure. The author finds no conclusive evidence that individual ejidos are significantly less productive than private farms, and hence, it seems unlikely that privatization of ejidos would greatly improve agricultural growth. He recommends the following improvements to the existing structure : giving the ejidatarios titles to their parcels of land, simplifying restrictions for private farmers on holding size and land use, ending restrictions on renting or sharecropping by ejidatarios, allowing ejidatarios to sell their land parcels to other members of their ejido, improving management of communal land, and extending credit directly to individual ejidatarios on the basis of their creditworthiness.Environmental Economics&Policies,Agricultural Knowledge&Information Systems,Banks&Banking Reform,Land Use and Policies,Rural Land Policies for Poverty Reduction

    Catheter-related bloodstream infection due to acinetobacter ursingii in a hemodialysis patient: Case report and literature review

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    35 páginasAcinetobacter ursingii is an anaerobic gram negative opportunistic coccobacillus, rarely isolated in bacteremic patients. It is mainly found in immunocompromised and severely ill patients with no identifiable source of infection. When isolated into the bloodstream, it usually displays resistance to at least two antimicrobial agents. To date only seven cases of bacteremia due to this microorganism have been reported in adults, of which, this accounts for the second one associated to renal replacement therapy and the first case of a documented catheter-related bloodstream infection (CRBSI) in a patient with a hemodialysis catheter. A 78-year-old male presented into the emergency department with acute kidney injury requiring hemodialysis, later developing bacteremia due to Acinetobacter ursingii. © Arsanios Martin Daniel et al

    Encephalitis and rapidly progressive dementia due to probable Prion disease presenting with a non-convulsive status epilepticus. Case report and literature review

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    Prion diseases are rare and rapidly progressive fatal neurological disorders characterized by abnormal folding of neuronal proteins. The diagnosis is often challenging and relies on a high clinical suspicion, imagenological findings, electroencephalographic (EEG) patterns and cerebrospinal fluid (CSF) analysis. We present a case of probable prion disease with an accelerated neurological decline and a non-convulsive status epilepticus (NCSE), which has only been described in a few cases worldwide, and seems to be associated with worse neurological outcomes and shorter survival time. Clinical manifestations, treatment, and outcomes are shown below. © 2024 Fundacion para la difusion neurologica en Ecuador - FUNDINE. All rights reserved

    Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in arabidopsis

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    Nitric oxide (NO) is a key signaling molecule in plants. This analysis of Arabidopsis thaliana HOT5 (sensitive to hot temperatures), which is required for thermotolerance, uncovers a role of NO in thermotolerance and plant development. HOT5 encodes S-nitrosoglutathione reductase (GSNOR), which metabolizes the NO adduct S-nitrosoglutathione. Two hot5 missense alleles and two T-DNA insertion, protein null alleles were characterized. The missense alleles cannot acclimate to heat as dark-grown seedlings but grow normally and can heat-acclimate in the light. The null alleles cannot heat-acclimate as light-grown plants and have other phenotypes, including failure to grow on nutrient plates, increased reproductive shoots, and reduced fertility. The fertility defect of hot5 is due to both reduced stamen elongation and male and female fertilization defects. The hot5 null alleles show increased nitrate and nitroso species levels, and the heat sensitivity of both missense and null alleles is associated with increased NO species. Heat sensitivity is enhanced in wild-type and mutant plants by NO donors, and the heat sensitivity of hot5 mutants can be rescued by an NO scavenger. An NO-overproducing mutant is also defective in thermotolerance. Together, our results expand the importance of GSNOR-regulated NO homeostasis to abiotic stress and plant development

    The role of endothelial frequency in the cerebral blood flow control during neonatal asphyxia: a retrospective longitudinal study

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    Background: Cerebral blood flow dynamics can be explored through analysis of endothelial frequencies. Our hypothesis posits a disparity in endothelial activity among neonates with perinatal asphyxia, stratified by the presence or absence of neuronal lesions. Methods: We conducted a retrospective longitudinal study involving newborns treated with hypothermia for moderate to severe asphyxia. Participants were grouped based on the presence or absence of neuronal damage to investigate temporal endothelial involvement in cerebral blood flow regulation. Regional cerebral oxygen saturation (rScO2) was measured using near-infrared spectroscopy (NIRS), and temporal series were analyzed in the frequency domain, utilizing the original frequency of the INVOS¿ device. Results: The study included 88 patients, with 53% (47/88) being male and 33% (29/88) demonstrating brain lesions on magnetic resonance imaging. Among them, 86% (76/88) had a gestational age exceeding 37 weeks according to the Ballard scale, and 81% (71/88) had a birth weight exceeding 2500 g. Cohen¿s d effect size was calculated to assess differences in endothelial frequency between groups, indicating a small effect size based on cerebral MRI findings (Cohen¿s d values for Day 2 = 0.2351 and Day 3 = 0.2325). Conclusion: NIRS represents a valuable tool for monitoring cerebral autoregulation in neonates affected by perinatal asphyxia, underscoring the utility of assessing endothelial frequency or energy on rScO2 measured by NIRS using the original INVOS¿ device frequency. © The Author(s) 2024

    The nature of the X-ray transient MAXI J0556−332

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    Phase-resolved spectroscopy of the newly discovered X-ray transient MAXIJ0556-332 has revealed the presence of narrow emission lines in the Bowen region that most likely arise on the surface of the mass donor star in this low-mass X-ray binary. A period search of the radial velocities of these lines provides two candidate orbital periods (16.43 ± 0.12 and 9.754 ± 0.048h), which differ from any potential X-ray periods reported. Assuming that MAXIJ0556-332 is a relatively high-inclination system that harbours a precessing accretion disc in order to explain its X-ray properties, it is only possible to obtain a consistent set of system parameters for the longer period. These assumptions imply a mass ratio of q≃ 0.45, a radial velocity semi-amplitude of the secondary of K 2≃ 190kms -1 and a compact object mass of the order of the canonical neutron star mass, making a black hole nature for MAXIJ0556-332 unlikely. We also report the presence of strong Niii emission lines in the spectrum, thereby inferring a high N/O abundance. Finally, we note that the strength of all emission lines shows a continuing decay over the ≃1 month of our observations

    Measurement of the Xi(-)(b) and Omega(-)(b) baryon lifetimes

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    Using a data sample of pp collisions corresponding to an integrated luminosity of 3 fb−1, the Ξ−b and Ω−b baryons are reconstructed in the Ξ−b → J/ψΞ− and Ω−b → J/ψΩ− decay modes and their lifetimes measured to be τ(Ξ−b) = 1.55+0.10−0.09 (stat) ± 0.03 (syst) ps, τ(Ω−b) = 1.54+0.26−0.21 (stat) ± 0.05 (syst) ps. These are the most precise determinations to date. Both measurements are in good agreement with previous experimental results and with theoretical predictions

    Effective lifetime measurements in the B-s(0) -> K+K-, B-0 -> K+pi(-) and B-s(0) -> pi K-+(-) decays

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    Measurements of the effective lifetimes in the View the MathML source, B0→K+π− and View the MathML source decays are presented using 1.0 fb−1 of pp collision data collected at a centre-of-mass energy of 7 TeV by the LHCb experiment. The analysis uses a data-driven approach to correct for the decay time acceptance. This is the most precise determination to date of the effective lifetime in the View the MathML source decay and provides constraints on contributions from physics beyond the Standard Model to the View the MathML source mixing phase and the width difference ΔΓs

    Measurement of the CP-violating phase phi(s) in (B)over-bar(s)(0) -> J / psi pi(+)pi(-) decays

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    The mixing-induced CP -violating phase ϕs in View the MathML source and View the MathML source decays is measured using the J/ψπ+π− final state in data, taken from 3 fb−1 of integrated luminosity, collected with the LHCb detector in 7 and 8 TeV centre-of-mass pp collisions at the LHC. A time-dependent flavour-tagged amplitude analysis, allowing for direct CP violation, yields a value for the phase ϕs=70±68±8 mrad. This result is consistent with the Standard Model expectation and previous measurements
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