203,561 research outputs found

    Refined shell elements for the analysis of functionally graded structures

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    The present paper considers the static analysis of plates and shells made of Functionally Graded Material (FGM), subjected to mechanical loads. Refined models based on the Carrera's Unified Formulation (CUF) are employed to account for grading material variation in the thickness direction. The governing equations are derived from the Principle of Virtual Displacement (PVD) in order to apply the Finite Element Method (FEM). A nine-nodes shell element with exact cylindrical geometry is considered. The shell can degenerate in the plate element by imposing an infinite radius of curvature. The Mixed Interpolation of Tensorial Components (MITC) technique is extended to the CUF in order to contrast the membrane and shear locking phenomenon. Different thickness ratios and orders of expansion for the displacement field are analyzed. The FEM results are compared with both benchmark solutions from literature and the results obtained using the Navier method that provides the analytical solution for simply-supported structures subjected to sinusoidal pressure loads. The shell element based on refined theories of the CUF turns out to be very efficient and its use is mandatory with respect to the classical models in the study of FGM structures. © 2011 Elsevier Ltd

    Take your "M" time

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    Both entry and exit from mitosis are driven through the fine modulation of Cdk1 activity by several proteins or protein complexes. It is well established that to enter into the M-phase a cell requires Cdk1 to be fully activated in the nucleus by the Cdc25A, B and C phosphatases. Then, at the onset of anaphase Cdk1 activity suddenly drops mainly due to Cyclin B1 degradation, thus allowing exit from M-phase. Recent data demonstrate that high Cdk1 activity is necessary also for proper chromosome segregation, since its premature drop determines acceleration of the progression from prophase to metaphase eventually with incorrect division of the DNA content. A primary role in maintaining high Cdk1 activity during prophase and metaphase is played by Cdc25C phosphatase. During the M-phase, the activity of Cdc25C is regulated by the FEZ1/LZTS1 (LZTS1) tumor suppressor gene, which is able to prevent Cdc25C degradation in mitotic cells. As a consequence, Lzts1 absence in mice results in accelerated mitotic progression, improper chromosome segregation and, eventually, in increased incidence of both spontaneous and carcinogen-induced cancer formation. © 2007 Landes Bioscience

    Standardizzazione per il contesto e la lingua italiana. Caratteristiche tecniche e metodologiche

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    Il contributo presenta le procedure statistiche ed i dati psicometrici e normativi della standardizzazione italiana della SIS

    Evoluzione di un paesaggio alpino alle sorgenti del Brembo (Carona, BG)

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    Il volume raccoglie una serie di contributi presentati nell’ambito del corso di alta formazione “Montagne e Archeologie”, organizzato come attività congiunta dei Corsi di Dottorato “Culture d’Europa”. Ambiente, spazi, storie arti, idee” (Università di Trento) e “Scienze archeologiche, storico-artistiche e storiche” (Università di Verona), a cura di Diego E. Angelucci, Enrico Croce, Mara Migliavacca e Fabio Saggioro. I casi-studio ricadono nell’ambito della cosiddetta “archeologia di montagna” e offrono esempi del lavoro archeologico alle alte quote o nelle aree vallive, significativi per suscitare sia la discussione metodologica sia la riflessione sulla presenza umana negli ecosistemi montani.he paper gives some insights of the data collected in the area of Carona (province of Bergamo, Italy) within the framework of the author’s PhD thesis. The main objective of the project is to understand the diachronic evolution of a mountain landscape shaped by human-environment interaction. The area was exploited for mining and pastoral activities from early medieval times; we also know that some kind of human occupation occurred in the area during the late Iron Age and the early Roman Age. The data collected through field survey, cartography, and archive study have been implemented through GIS and statistical analysis. The main type of evidence detected are the mountain huts (baite), along with pastoral structures, charcoal production sites and mining assemblages. The analysis of structural decay and cartographic presence of baite lead to the definition of a built landscape chronology. The main outcome is the reconstruction, at different levels of accuracy, of the landscape evolution from Iron Age to the present time. The proposed methodology, as a synthesis of different research experiences in the mountain environment, could lay the foundations for a broader reflection on possible shared and common approaches to “mountain archaeology” as an autonomous archaeological field of research

    Analisi stratigrafica della basilica di Santa Croce

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    Nuove ricerche archeologiche sul complesso placidiano di Santa Croce a Ravenna. Sono presentate le analisi stratigrafiche svolte dal Dipartimento di Archeologia dell'Università di Bologna tra il 2006 e il 2013 sul complesso architettonico di Santa Croce a Ravenna

    La croce dei pisani

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    Symbolic and religious use of the early XV century silver gilded cross called "Croce dei Pisani"

    Structural evolution of the M. Gottero Unit in the M. Zatta-M. Ghiffi sector, Ligurian-Emilian Apennines, Italy

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    The Mt. Gottero unit, Northern Apennines, belongs to the Ligurid units s.l. and is tectonically situated below the Mt Antola unit and above the Braco/Val Graveglia, Colli/Tavarone and Helminthoid flysch units. This unit displays a very complex structural pattern due to the superimposition of several deformational phases. The presence of wide areas where the Mt. Gottero unit is characterized by structural directions oblique to the regional trend constitutes a matter of debate. A structrural analysis of the Mt. Zatta-Mt. Ghiffi area (Ligurian-Emilian Apennine) which is representative of the existing structural problems of the Mt. Gottero unit, is presented here

    Risorse idriche e ambiente montano: uno studio di caso dalla Val Molinac (TN)

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    This paper focusses on the use of water in the Alpine uplands, through the case-study of Val Molinac (Val di Sole, Trento, Italy). In this valley, at an elevation of approximately 2100 to 2450 m, a complex system of irrigation canals has been identified during survey campaigns in 2020 and 2021, in the context of project ALPES. Archaeological data have been complemented by GIS and statistical analysis, as well as ethnoarchaeological information provided by local community members. A cluster of canals has been detected on the western slope of Val Molinac. The canals were used for watering a restricted sector of the valley, which was devoted to hay making. Data collected from historical maps and the cadastre indicate that this system was traced prior to 1859. Another water canal, named MZ155C, is found on the eastern slope of the valley. This feature, almost 2.5 km long, carries water from Lago di Ortisé (2445 m) to Malga Bronzolo (2090 m) and was also built before 1859. The data collected and their contextualisation in the Alpine landscape of Val di Sole are useful to understand historical land use and the exploitation of natural resources (such as water and grass), as well as to reconstruct the formation of upland pastoral landscapes in this sector of the Alps

    Moral Understanding, Testimony, and Moral Exemplarity

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    While possessing moral understanding is agreed to be a core epistemic and moral value, it remains a matter of dispute whether it can be acquired via testimony and whether it involves an ability to engage in moral reasoning. This paper addresses both issues with the aim of contributing to the current debates on moral understanding in moral epistemology and virtue ethics. It is argued that moral epistemologists should stop appealing to the argument from the transmissibility of moral understanding to make a case for their favorite view of moral understanding. It is also argued that proponents of exemplarist moral theories cannot remain neutral on whether the ability to engage in moral reasoning is a necessary component of moral understanding. © 2019, The Author(s)
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