15 research outputs found
AUTHOR REPLY
No full textWe read with interest the comments by Corse and colleagues on our recently published paper about the use of indocyanine green (ICG) enabling the overlap of the 3D virtual kidney model over the real organ during surgery. The Authors present insightful comments on the new presented technology
Deolindo Checcucci e o teatro infantil baiano no contexto da ditadura militar: arquivo, edição e estudo crítico filológico.
Get PDFTheater, during the 1970s and 1980s, had a remarkable development, even in a society
controlled by the Military Dictatorship, which was established in the national territory
between 1964 and 1985, restricting freedom of expression through censorship. In this
context, we highlight the dramaturgy of Deolindo Checcucci, author who has been
producing in Bahia since the 1970s. Characterized as a multifaceted artist, Checcucci
takes on the roles of director, teacher and playwright in the Bahian theatrical scenario.
Through his children's productions, he sought to develop a critical and innovative
theater, able to promote reflection and social change. We can observe these
characteristics through Deolindo Checcucci's Collection - Children's Theater,
organized by the Team of Censored Theatrical Texts, coordinated by Professor Rosa
Borges, at the Federal University of Bahia, since 2006. This thesis will focus on the
study of the children's dramaturgy of Deolindo Checcucci, from the organization of the
collection, the edition and the critical-philological study of selected texts, gathered in a
Hypertextual Archive. Thus, through a dialogue among Philology, Archivistics and
computer technologies, it is possible to analize critically the dramaturgical production
of Deolindo Checcucci and configure the paths taken by Bahian children's theater
during the Military Dictatorship in Bahia.O teatro, durante as décadas de 1970 e 1980, teve notável desenvolvimento, mesmo em
uma sociedade controlada pela Ditadura Militar, que foi instaurada em território
nacional entre 1964 e 1985, restringindo a liberdade de expressão, através da censura.
Nesse contexto, destacamos a dramaturgia de Deolindo Checcucci, autor que produz na
Bahia desde a década de 1970. Caracterizando-se como um artista multifacetado,
Checcucci assume no cenário teatral baiano os papéis de diretor, professor e
dramaturgo. Através de suas produções infantis, buscou desenvolver um teatro crítico e
inovador, capaz de promover a reflexão e a mudança social. Podemos observar essas
características através do Acervo Deolindo Checcucci – Teatro Infantil (ADC-TI),
organizado no âmbito da Equipe Textos Teatrais Censurados – ETTC, coordenada pela
professora Dra. Rosa Borges, na Universidade Federal da Bahia – UFBA, desde 2006.
A presente tese terá como enfoque o estudo da dramaturgia infantil de Deolindo
Checcucci, a partir da organização do acervo, da edição e do estudo crítico-filológico de
textos selecionados, reunidos em um Arquivo Hipertextual. Desse modo, mediante o
diálogo entre a Filologia, a Arquivística e as tecnologias informáticas, podemos analisar
criticamente a produção dramatúrgica de Deolindo Checcucci e, a partir dela, configurar
os caminhos percorridos pelo teatro infantil baiano durante a Ditadura Militar na Bahia
Author Correction: Metaverse in surgery — origins and future potential (Nature Reviews Urology, (2024), 10.1038/s41585-024-00941-4)
No full textCorrection to: Nature Reviews Urologyhttps://doi.org/10.1038/s41585-024-00941-4, published online 30 September 2024. In the version of the article initially published, Enrico Checcucci was wrongly stated to be affiliated with the University of Verona. This has now been amended in the HTML and PDF versions of the article so that Enrico Checcucci’s only affiliation is Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Turin, Italy
Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) during robot-assisted radical prostatectomy: a systematic review and meta-analysis of comparative studies
No full textBackgroundTo compare surgical, pathological, and functional outcomes of patients undergoing NeuroSAFE-guided RARP vs. RARP alone.MethodsIn February 2024, a literature search and assessment was conducted through PubMed (R), Scopus (R), and Web of Science (TM), to retrieve data of men with PCa (P) undergoing RARP with NeuroSAFE (I) versus RARP without NeuroSAFE (C) to evaluate surgical, pathological, oncological, and functional outcomes (O), across retrospective and/or prospective comparative studies (Studies). Surgical (operative time [OT], number of nerve-sparing [NS] RARP, number of secondary resections after NeuroSAFE), pathological (PSM), oncological (biochemical recurrence [BCR]), and functional (postoperative continence and sexual function recovery) outcomes were analyzed, using weighted mean difference (WMD) for continuous variables and odd ratio (OR) for dichotomous variables.ResultsOverall, seven studies met the inclusion criteria (one randomized clinical trial, one prospective non-randomized trial and five retrospective studies) and were eligible for SR and MA. A total of 4,207 patients were included in the MA, with 2247 patients (53%) undergoing RARP with the addition of NeuroSAFE, and 1 960 (47%) receiving RARP alone. The addition of NeuroSAFE enhanced the likelihood of receiving a nerve-sparing (NS) RARP (OR 5.49, 95% CI 2.48-12.12, I2 = 72%). In the NeuroSAFE cohort, a statistically significant reduction in the likelihood of PSM at final pathology (OR 0.55, 95% CI 0.39-0.79, I2 = 73%) was observed. Similarly, a reduced likelihood of BCR favoring the NeuroSAFE was obtained (OR 0.47, 95% CI 0.35-0.62, I2 = 0%). At 12-month postoperatively, NeuroSAFE led to a significantly higher likelihood of being pad-free (OR 2.01, 95% CI 1.25-3.25, I2 = 0%), and of erectile function recovery (OR 3.50, 95% CI 2.34-5.23, I2 = 0%).ConclusionAvailable evidence suggests that NeuroSAFE might represent a histologically based approach to NVB preservation, broadening the indications of NS RARP, reducing the likelihood of PSM and subsequent BCR. In addition, it might translate into better functional postoperative outcomes. However, the current body of evidence is mostly derived from non-randomized studies with a high risk of bias
Hyper accuracy three-dimensional virtual anatomical rainbow model facilitates surgical planning and safe selective clamping during robot-assisted partial nephrectomy
Get PDFObjective: To highlight the role of hyper accuracy three-dimensional (3D) reconstruction in facilitating surgical planning and guiding selective clamping during robot-assisted Methods: A transperitoneal RAPN was performed in a 62-year-old male patient presenting with a 4 cm right anterior interpolar renal mass (R.E.N.A.L nephrometry score 7A). An abnormal vasculature was observed, with a single renal vein and two right renal arteries originating superiorly to the vein and anterior, when dividing in their segmental branches. According to the one of the segmental arteries was feeding the tumor. This allowed for an accurate prediction of the area vascularized by each arterial branch. The 3D model was included in the intraoperative console view during the whole procedure, using the TilePro feature. A step-by-step explanation of the procedure is provided in the video attached to the present article. Results: The operative time was 90 min with a warm ischemia time on selective clamping of 13 min. Estimated blood loss was 180 mL. No intraoperative complication was encountered and no drain was placed at the end of the procedure. The patient was discharged on postoperative Day 2, without any early postoperative complications. The final pathology report showed a pathological tumor stage 1 clear cell renal cell carcinoma with negative surgical margins. Conclusion: The present study and the attached video illustrate the value of 3D rainbow model during the planning and execution of a RAPN with selective clamping. It shows how the surgeon can rely on this model to be more efficient by avoiding unnecessary surgical steps, and to safely adopt a "selective" clamping strategy that can translate in minimal functional impact. (c) 2024 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/)
Telehealth in Urology: A Systematic Review of the Literature. How Much Can Telemedicine Be Useful During and After the COVID-19 Pandemic?
Get PDFCoronavirus disease 2019 (COVID-19) pandemic has caused increased interest in the application of telehealth to provide care without exposing patients and physicians to the risk of contagion. The urological literature on the topic is sparse
The prognostic role of next-generation imaging-driven upstaging in newly diagnosed prostate cancer patients
No full text\ua9 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Phase III evidence showed that next-generation imaging (NGI), such as prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT), provides higher diagnostic accuracy than bone scan and contrast-enhanced computed tomography (conventional imaging, CI) in the primary staging of intermediate-to-high-risk prostate cancer (PCa) patients. However, due to the lack of outcome data, the introduction of NGI in routine clinical practice is still debated. Analysing the oncological outcome of patients upstaged by NGI (though managed according to CI) might shed light on this issue, supporting the design of randomised trials comparing the effects of treatments delivered based on NGI vs. CI. Methods: We prospectively enrolled a cohort of 100 biopsy-proven intermediate-to-high-risk PCa patients staged with CI and PSMA PET/CT (though managed according to the CI stage), to assess the frequency of the stage migration phenomenon. Stage migration was then assessed as biochemical recurrence—free survival (bRFS) predictor. Results: Three patients were lost at follow-up after imaging. PSMA PET/CT upstaged 26.8% of patients compared to CI, while it downstaged 6.1% of patients. Notably, 50% of patients excluded from surgery due to the presence of bone metastases at CI would have been treated with radical-intent approaches if PSMA PET/CT had guided the treatment choice. After a median follow-up of 6 months of surgically treated patients, 22/83 (26.5%) had biochemical recurrence (BCR). PSMA PET/CT-driven upstaging determined a significant risk increase for BCR (HR:3.41, 95%CI:1.21–9.56, p = 0.019). Including stage migration in a univariable and multivariable model identified PSMA PET/CT-upstaging as an independent predictor of bRFS. Conclusions: In conclusion, implementing NGI for staging purposes improves the prediction of bRFS. Although phase III evidence is still needed, this advancement suggests that NGI may better identify patients who would benefit from local treatments than those who may achieve better oncological outcomes through systemic treatment
Single-Port Robot-Assisted Radical Prostatectomy: Where Do We Stand?
No full textIn 2018, the da Vinci Single Port (SP) robotic system was approved by the US Food and Drug Administration for urologic procedures. Available studies for the application of SP to prostate cancer surgery are limited. The aim of our study is to summarize the current evidence on the techniques and outcomes of SP robot-assisted radical prostatectomy (SP-RARLP) procedures. A narrative review of the literature was performed in January 2023. Preliminary results suggest that SP-RALP is safe and feasible, and it can offer comparable outcomes to the standard multiport RALP. Extraperitoneal and transvesical SP-RALP appear to be the two most promising approaches, as they offer decreased invasiveness, potentially shorter length of stay, and better pain control. Long-term, high-quality data are missing and further validation with prospective studies across different sites is required
Searches for lepton number violating K+→π− (π0)e+e+ decays
Get PDFSearches for lepton number violating K+ -> pi(-)e(+)e(+) and K+ -> pi(-)pi(0)e(+)e(+) decays have been performed using the complete dataset collected by the NA62 experiment at CERN in 2016-2018. Upper limits of 5.3 x 10(-11 )and 8.5 x 10(-10) are obtained on the decay branching fractions at 90% confidence level. The former result improves by a factor of four over the previous best limit, while the latter result represents the first limit on the K+ -> pi(-)pi(0)e(+)e(+) decay rate. (C) 2022 The Author. Published by Elsevier B.V
