197,242 research outputs found

    Assessment of a topical product based on a mixture of polysulfated galactosaminoglycan in the topical treatment of postoperative blood extravasation (ecchymosis-hematoma) in phlebology

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    BACKGROUND: The onset of bruising in surgery is a frequent event that can be a source of complications and delays in the patient’s healing process (pigmentations, fibrosis, etc.). Having the help of an effective topical product that speeds up the resorption of blood extravasation can be an advantage in phlebological surgery and surgery in general. METHODS: Twenty-three patients both male and female (age range: 30-72 years) were enrolled. Twenty-two of them completed the study, all underwent venous surgery of the lower extremities (invagination stripping of the internal or external saphenous and Muller’s ambulatory phlebectomy). The 22 patients were divided into 2 groups of 11 each and in a single blind study received topical daily therapy (every 12 hours) either in the form of a medication cream (active ingredient), or a placebo cream. All patients wore compression one-leg tights immediately after surgery, following measurement of the lower limb (Struva®35 mmHg, Medi Italia, Zola Predosa, Bologna, Italy). The 30-day observational study was carried out using a standard photographic survey procedure. RESULTS: The topical application of polysulfated galactosaminoglycan showed a significantly higher rate of resorption of blood extravasations than in patients in the single blind study receiving topical therapy with the placebo (Fisher’s Exact Test, dichotomous variable outcome, N.=22, with result P=0.0001<0.05). CONCLUSIONS: Topical therapy with a mixture of polysulfated galactosaminoglycans provides valid protection in the therapy of blood extravasations in phlebology and general surgery. (Cite this article as: izzo M, coscia v. assessment of a topical product based on a mixture of polysulfated galactosaminoglycan in the topical treatment of postoperative blood extravasation (ecchymosis-hematoma) in phlebology

    On the Equivalence Between Community Discovery and Clustering

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    Clustering is the subset of data mining techniques used to agnostically classify entities by looking at their attributes. Clustering algorithms specialized to deal with complex networks are called community discovery. Notwithstanding their common objectives, there are crucial assumptions in community discovery – edge sparsity and only one node type, among others – which makes its mapping to clustering non trivial. In this paper, we propose a community discovery to clustering mapping, by focusing on transactional data clustering. We represent a network as a transactional dataset, and we find communities by grouping nodes with common items (neighbors) in their baskets (neighbor lists). By comparing our results with ground truth communities and state of the art community discovery methods, we show that transactional clustering algorithms are a feasible alternative to community discovery, and that a complete mapping of the two problems is possible

    Existence and uniqueness of steady, fully developed flows of second order fluids in curved pipes by a splitting method

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    Steady, fully developed flows of second order fluids in curved pipes of circular cross-section have previously been studied using regular perturbation methods. These perturbation solutions are applicable for pipes with small curvature ratio: The cross sectional radius of the pipe divided by the radius of curvature of the pipe centerline. It was shown by Jitchote and Robertson that perturbation equations could be ill-posed when the second normal stress coefficient is nonzero. Motivated by the singular nature of the perturbation equations, here, we study the full governing equations without introducing assumptions inherent in perturbation methods. In particular, we examine the existence and uniqueness of solutions to the full governing equations for second order fluids. We show rigorously that a solution to the full problem exists and is locally unique for small non-dimensional pressure drop, in agreement with earlier results obtained using a formal expansion in thecurvature ratio.12 The results obtained here are valid for arbitrarily shaped cross-section (sufficiently smooth) and for all curvature ratios. An operator splitting method has been employed which may be useful for numerical studies of steady and unsteady flows of second order fluids in curved pipes

    The role of free iron in cardiovascular diseases - Part I

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    An unavoidable consequence of the aerobic mechanism is the production of super-oxides and peroxides known as "Reactive Oxygen Species" (ROSs). These substances can trigger a number of biological reactions not particularly dangerous at physiological concentration. However, in presence of iron such reactions greatly enhance the radicals production and, in particular, determine the release of strongly reactive and toxic radicals as the hydroxyl radical (OH.). Many chronic inflammatory conditions share this underlying disequilibrium of the iron induced radical-antiradical balance. Aim of the present review is to enlighten the role of the free or weakly chelated portion of iron in vascular and cardiac diseases

    Modelli matematici del traffico veicolare - Istituto Nazionale di Alta Matematica

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    Il progetto è stato finanziato a seguito ad un bando competitivo dell'Istituto Nazionale di Alta Matematica. Scopo del progetto è stata l'identificazione e l'analisi di modelli matematici del traffico veicolare a diverse scale di osservazione e in diversi frameworks analitici e computazionali. Esso ha visto il coinvolgimento di diverse sedi universitarie (Ferrara, Torino-Politecnico, Bologna, Perugia, Roma-La Sapienza, Palermo) e circa una ventina di ricercatori. Nell'ambito del progetto è stato organizzato a Ferrara, nei giorni 8-9 Maggio 2003, un workshop internazionale su “Mathematical Models and Methods in the Study of Traffic Flow”. Il workshop, che ha ospitato due keynote lectures da parte di D. Helbing, ora al Politecnico di Zurigo, e di M. Rascle dell'Università di Nizza, ha visto la partecipazione di numerosi studiosi, provenienti sia dall'ambito matematico che ingegneristico. Nell'ambito del progetto sono stati prodotti diversi lavori usciti a stampa

    Developing Social and Communication Skills in Autistic Children Through Mediated Peer Groups

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    Establishing a social media portal to ease creation of peer groups for parents and familiesFall 2012Accompanied by video fil

    On the Mathematical Theory of Vehicular Traffic Flow I - Fluid Dynamic and Kinetic Modeling

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    This review reports the existing literature on traffic flow modelling in the framework of a critical overview which aims to indicate research perspective. The contents mainly refer to modelling by fluid dynamic and kinetic equations and are arranged in three parts. The first part refers to methodological aspects of mathematical modelling and to the interpretation of experimental results. The second part is devoted to modelling and deals both with methodological aspects and with the description of some specific models. The third part reports about an overview on applications and research perspectives
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