1,721,375 research outputs found
Untargeted antifungal treatment in nonneutropenic critically Ill patients: Should further studies be performed based on trial sequential analysis results?
No full textWhy, whether and how to use high-flow nasal therapy in acute exacerbations of chronic obstructive pulmonary disease
No full textNoninvasive ventilation (NIV) represents the standard of care for respiratory support of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) developing acute hypercapnic respiratory failure (AHRF) [1]. NIV has been shown to reduce patient’s work of breathing and mortality and be feasibly implemented in various hospital location facilities at different timing, based on the severity of AHRF [2] and it is also widely used in clinical practice by physicians [3]. However, clinicians’ knowledge, experience and expertise in the management of NIV are crucial for its success in order to overcome common problems that may lower its effectiveness such as patients’ discomfort due to the interfaces (e.g., tight-fitting face masks), excessive air leaks from the masks and patient–ventilator asynchrony. Thus, despite improvements in mask and ventilator technology to enhance patients’ comfort and clinicians’ optimization of ventilator settings to improve patient–ventilator interactions, NIV tolerance is still a major issue that can cause NIV failure with rates ranging from 5 to over 50% [4].
The relatively recent introduction into clinical practice of high-flow nasal therapy (HFNT) as a new noninvasive respiratory support led to growing reports on the potential role of this technique in these setting
Out-of-hospital cardiac arrest during the COVID-19 era: The importance to fight against fear
No full textIntentional interruptions during compression only CPR: a way to increase adherence to CPR and compressions' quality?
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Incidence Of Unplanned Extubation In French Intensive Care Units: Are We Ready For A Safe-Icu Plan!
No full textLiberation from mechanical ventilation is an important decision in Intensive Care’s everyday clinical practice. It includes the evaluation of the readiness of patients to be able to breathe spontaneously, without assistance, and the last step of this pathway is extubation. Extubation failure and reintubation are associated with increased risk of mortality, thus understanding the correct timing of extubation is crucial. For these reasons, extubation is usually a planned clinical decision, followed by a post-extubation plan to reduce reintubation ris
Being candid about Candida airway colonization and clinical outcomes: What can we really learn from unadjusted associations?
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