1,108 research outputs found
Unveiling Melodies in Shadows: An Analysis of Swedish Female Composer Amanda Maier’s Sonata for Violin and Piano in B Minor
No full textAmanda Maier (1853−1894), a pioneering Swedish violinist and composer of the late nineteenth century, holds a unique place in music history as the first-ever female music director in Sweden. Despite her significant achievements, her compositions have remained relatively unknown. Therefore, the document aims to illuminate Amanda Maier's violin works, focusing on investigating her violin sonata in terms of violin performance and pedagogy. Specifically, the study offers insights into the performance techniques employed and provides other pertinent pedagogical suggestions for each movement. The document features an introductory chapter and a review of the historical context of Maier's life and the violin sonata. Subsequent chapters shift the focus to performance practice and pedagogical suggestions with theoretical analysis. One distinctive feature of the study is the inclusion of practice exercises composed originally by the author, tailored specifically to the techniques found in the sonata. These exercises aid practitioners in incorporating Maier's violin sonata into their program. The study assists violinists in diversifying their performance and teaching literature. It seeks to inspire renewed appreciation for Amanda Maier's artistic legacy because it is important to recognize the remarkable contributions of women in the classical music industry, and Amanda Maier, an underrepresented composer, exemplifies this. The document not only contributes to music research but also enhances pedagogical practices, fostering a more inclusive and equitable environment for female composers in the classical music world
Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: Evidence for a role in hepcidin induction by inflammation in male mice
No full textInduction of the iron regulatory hormone hepcidin contributes to the anemia of inflammation. Bone morphogenetic protein 6 (BMP6) signaling is a central regulator of hepcidin expression in the liver. Recently, the TGF-β/BMPsuperfamily member activin B was implicated in hepcidin induction by inflammation via noncanonical SMAD1/5/8 signaling, but its mechanism of action and functional significance in vivo remain uncertain. Here, we show that low concentrations of activin B, but not activin A, stimulate prolonged SMAD1/5/8 signaling and hepcidin expression in liver cells to a similar degree as canonical SMAD2β signaling, and with similar or modestly reduced potency compared with BMP6. Activin B stimulates hepcidin via classical activin type II receptors ACVR2A and ACVR2B, noncanonical BMP type I receptors activin receptor-like kinase 2 and activin receptorlike kinase 3, and SMAD5. The coreceptor hemojuvelin binds to activin B and facilitates activin B-SMAD1/5/8 signaling. Activin B-SMAD1/5/8 signaling has some selectivity for hepatocyte-derived cells and is not enabled by hemojuvelin in other cell types. Liver activin B mRNA expression is up-regulated in multiple mouse models of inflammation associated with increased hepcidin and hypoferremia, including lipopolysaccharide, turpentine, and heat-killed Brucella abortus models. Finally, the activin inhibitor follistatin-315 blunts hepcidin induction by lipopolysaccharide or B. abortus in mice. Our data elucidate a novel mechanism for noncanonical SMAD activation and support a likely functional role for activin B in hepcidin stimulation during inflammation in vivo
Groundwater resources of the Harney Basin, southeastern Oregon
No full textauthors: Stephen B. Gingerich, C. Amanda Garcia, and Henry M. Johnson.Title from PDF caption (viewed on November 22, 2022).This archived document is maintained by the State Library of Oregon. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page 6).Mode of access: Internet from the State Library of Oregon U.S. Government Publications Collection.Text in English
Adaptation of the Australian core food groups to enable planning of vegan and lactovegetarian diets
No full textThis work demonstrates how the Australian core food groups system can be modified to enable the planning of vegan and lactovegetarian diets as well as omnivorous diets. In the modified version the cereals, vegetables and fruits groups remain the same as in the core food groups system, while the meat group is replaced with legumes, soya products, nuts and seeds. The milk group becomes milk or fortified soya milk, to allow for both lactovegetarian and vegan diets. The core food groups standard of 70% of the recommended dietary intake was adopted as a target for determining recommendations on the minimum number of serves from each food group. As found in the development of the core food groups system, zinc was the most limiting nutrient. Vitamin B 12 and calcium were other limiting nutrients in the vegan and lactovegetarian guides. The number of serves from each group required to meet 70% of the applicable recommended dietary intake has been calculated for children from four years old, adult men and women and pregnant and lactating women. It was found that the number of serves from each food group required in the vegan and lactovegetarian planning guides was in most cases similar to the number of serves of corresponding core food groups specified for a particular population group. This suggests that the vegan and lactovegetarian planning guides could be incorporated into a modified core food groups planning guide. Such a guide would cater for the general omnivorous population as well as for those seeking to avoid meat and/or dairy products. (Aust J Nutr Diet 1999:56:22-30)\ud
Key words: vegan, vegetarian, food guide, food groups, dietary planning
Generation of high throughput transduction tools and evaluation of the role od BMP2/4 in late morphogenesis in sea urchin embryos
No full textThesis (Ph.D.)--Boston University
PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [email protected]. Thank you.The sea urchin embryo has recently emerged as a powerful model organism for systems-level studies aimed at understanding developmental complexity; however, the tools available for high throughput transgenic approaches are limited. Toward that end, the goal of part one of this study was to engineer pantropic retroviruses (PRVs) for genetic perturbations of urchin embryos at a scale suitable for systems-level measures. To insert sea urchin enhancers and simultaneously disrupt the endogenous viral enhancer, we used a viral self-inactivation (SIN) strategy with the Otx cis-regulatory module 3 (CRM3) enhancer, which drives ubiquitous and maternal-plus-zygotic expression in sea urchin embryos. We found that such PRVs are genomically integrated into sea urchin zygotes at a copy number of one, and that Otx CRM3-driven transgene expression initiates in the 2-cell stage, and is global and persistent. To transduce bicistronic messages, we validated the cricket paralysis virus (CrPV) internal ribosomal entry site (IRES) in sea urchins, and successfully developed SIN PRVs that express CrPV IRES-dependent bicistronic messages. Finally, we utilized Otx CRM3 to successfully drive functional antisense (AS) sequences for bone morphogenetic protein 2/4 (BMP2/4) or Delta; embryos transduced with these AS-expressing viruses exhibit the expected phenotypes, validating this approach. Together these results establish a foundation for SIN PRVs as a tool for studying sea urchin development. Part two of this study focuses on the role of BMP2/4 signaling in sea urchin development. BMP2/4 is required for dorsal specification, and our early study showed that Chordin, a dedicated BMP antagonist, inhibits BMP2/4 at the dorsal-ventral (DV) boundary, promoting "peripheral" neurogenesis in that territory. Our more recent efforts utilized blastomere injections to generate embryos in which BMP2/4 was blocked in half of the embryo, which results in expansion of the ventral territory, but overall retention of DV patterning. The results demonstrate that BMP2/4 signals via SMAD1/5/8 to induce the morphogenesis of the oral hood. This structure develops from the apical plate, and BMP2/4 is not required for apical specification, indicating that BMP2/4 is required downstream of that early step. The apical plate also gives rise to the "central" serotonergic neurons, and our results indicate that BMP2/4 is directly required for serotonergic neural development
Partner Facilitation and Partner Interference in Individuals' Weight Loss Goals
No full textDrawing on the logic of the relational turbulence model, this study examined the ways in which romantic partners facilitate and interfere with individuals’ weight loss goals. Participants (N = 122) described the ways in which their romantic partner had recently helped or hindered their weight loss at four times over the course of 2 months. We conducted a content analysis of responses to identify themes of partner facilitation (Research Question 1 [RQ1]) and partner interference (RQ2) in individuals’ weight loss goals. Results revealed seven themes of partner facilitation: (a) partner enabling diet, (b) motivation and encouragement, (c) emotional support and positive reinforcement, (d) exercising together, (e) partner enabling exercise, (f) dieting together, and (g) relationship influence and priorities. Four themes of partner interference emerged in the data: (a) inability to plan for healthy meals, (b) inability to control the food environment, (c) preventing or discouraging exercise, and (d) emotional or relational discouragement.Peer reviewe
Groundwater resources of the Harney Basin, southeastern Oregon
No full textReport -- Plate 1. Location of Selected Geographic Features, Wells, Springs, Streamgaging Stations, Section Traces, and Sampling Locations, Harney Basin, Southeastern Oregon -- Plate 2. Water-Table Contour Map, 2018, Harney Basin, Southeastern Oregon -- Plate 3. Water-Level Contour Map for Wells Greater than 100 Feet Deep, 2018, Harney Basin, Southeastern Oregon.by Stephen B. Gingerich, Henry M. Johnson, Darrick E. Boschmann, Gerald H. Grondin, and C. Amanda Garcia ; prepared in cooperation with the Oregon Water Resources Department.Title from PDF title page (viewed on May 2, 2022).This archived document is maintained by the State Library of Oregon. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the State Library of Oregon U.S. Government Publications Collection.Text in English
'A little easy and modern for the times' : a documentary of productions of Ben Jonson's plays by major professional theatre companies in England, 1977-2000
No full textThis thesis is a collation and discussion of productions of Ben Jonson's plays in
England between 1977 and 2000. It focuses on mainstream theatre productions.
Therefore, amateur and Fringe productions, adaptations and productions by
small-scale theatre companies are not included. It contains previously unreleased
material of interviews with theatre practitioners who have been instrumental in
staging the productions covered.
Whilst scholarship has concentrated on recent productions of
Shakespeares, tudies in Jonsonianp erformanceh ave been neglected.W ith the
recent resurgence in popularity of Jonson's texts in the English theatre repertoire,
it is now pertinent to assessth e methodsu sed to staget he work of this
playwright. This thesis focuses only on the staging of texts presented between the
two dates; this does not cover all of Jonson's texts. Contained in two volumes,
Part One raises issues of performance, whilst in Part Two productions are
considered within chapters on each play. An Afterword (in Volume One)
considers the future of production and the action needed to be taken for future
progression in performance and performance studies. The Appendix (in Volume
One) contains detailed venue information. The thesis is intended as a
documented record of productions, in order to stimulate future research into
Jonsonian performance methods. By examining recent productions the failures
and successeso f the contemporaryt heatre's approacht o Jonsonh ave been noted.
This will contribute to an understanding of how Jonson's texts continue to work
on stage. The title of this thesis comes from Bartholomew Fair, a play that
addressesth e need to assimilatet he presentationo f theatre within contemporary
concerns
An Analytical Study of Amanda Harberg’S Sonata for B-Flat Clarinet and Piano
No full textDespite growing interest in equal representation of living female composers, scholarly work on the subject remains fairly limited. Several musicians and authors have begun to address this issue by compiling online lists of composers who are among the underrepresented in their blogs or on their websites, and though these compilations are wonderful sources from which to start a search, very few focus on living female composers who are from the United States, and even fewer include those who have written for the clarinet. One such composer is Amanda Harberg, a Philadelphia-born pianist, composer, and educator living in New Jersey. Among her extensive compositional output are seven original works for clarinet, the Sonata being the only piece that is not a chamber work, and thus her first piece that utilizes the clarinet as a solo voice. The document begins with a thorough biography of Amanda Harberg, including discussion of her compositional style and musical inspirations and a list of her original solo and chamber works for clarinet. The succeeding chapter presents a background history and overview of the Sonata for B-Flat Clarinet and Piano. An in-depth analysis of each movement of the work is presented in Chapters 3 through 5, followed by the document conclusion in Chapter 6. The analytical and compositional concepts discussed throughout the body of the document are further illustrated through tables and musical examples. The appendices contain the transcription of an in-person interview conducted by the author, a complete chronological compilation of Harberg’s compositional output, and a list of her awards and honors to date. The intent of this document is to provide future performers and researchers a tool with which to enhance their own studies of this piece and this composer, expanding upon the academic writings on the subject of women composers for years to come
Blue Radiance
No full textDegree Awarded: D.M.A. Composition. The Catholic University of AmericaBlue Radiance - Amanda Bono (b. 1987) for Large Ensemble "Over everything lay a peculiar blue radiance, as if it were surrounded by the air from above, through which the blue sky shone, instead of the dark depths of the sea." The Little Mermaid, Hans Christian Andersen I. Below the Surface II. The Mermaid III. The Fathomless Deep IV. To Prepare the Magic Draught V. Among the Daughters of the Air Instrumentation,Flute,Oboe,Clarinet in A,Bassoon,Horn in F,Trumpet in C (doubling Flugelhorn)Trombone,Tuba,Percussion,Marimba,Vibraphone,Small tam-tam,Triangle,Piano,Strings,Violin I,Violin II,Viola,Cello,Double Bas
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