24,768 research outputs found
Pioneer personal history, Mary Henrie Cooper
No full textTypescript of answers by Mary Henrie Cooper of Panguitch, Utah, for a questionnaire filled out for Utah Works Progress Administration\u27s "Pioneer personal history" survey. She was born in 1866 at Panaca, Nevada, when it was part of Washington County, and the family moved in 1871 to Panguitch. Includes copy of a statement by her father, James Henrie, who met Joseph Smith at Nauvoo, and details of her mother, Christina Schow Henrie. Typed by David Kern Owens of Panguitch in 193
Pioneer personal history questionnaire: Mrs. Mary Ophelia Cooper Myers
No full textTypescript of answers by Mary Ophelia (Cooper) Myers of Panguitch, Utah for a questionnaire filled out for Utah Works Progress Administration\u27s "Pioneer personal history" survey. She was born at Salem, Utah, and the family moved south in 1866 and settled at Panguitch in 1871. Her husband became a mail deliverer. Transcript by David Kern Owens of Panguitch, dated October 7, 193
Evolution of cooperation among tumor cells
No full textThe evolution of cooperation has a well established theoretical framework based on game theory. This approach has made valuable contributions to a wide variety of disciplines, including political science, economics, and evolutionary biology. Existing cancer theory suggests that individual clones of cancer cells evolve independently from one another, acquiring all of the genetic traits or hallmarks necessary to form a malignant tumor. It is also now recognized that tumors are heterotypic, with cancer cells interacting with normal stromal cells within the issue microenvironment, including endothelial, stromal, and nerve cells. This tumor cell???stromal cell interaction in itself is a form of commensalism, because it has been demonstrated that these nonmalignant cells support and even enable tumor growth. Here, we add to this theory by regarding tumor cells as game players whose interactions help to determine their Darwinian fitness. We marshal evidence that tumor cells overcome certain host defenses by means of diffusible products. Our original contribution is to raise the possibility that two nearby cells can protect each other from a set of host defenses that neither could survive alone. Cooperation can evolve as byproduct mutualism among genetically diverse tumor cells. Our hypothesis supplements, but does not supplant, the traditional view of carcinogenesis in which one clonal population of cells develops all of the necessary genetic traits independently to form a tumor. Cooperation through the sharing of diffusible products raises new questions about tumorigenesis and has implications for understanding observed phenomena, designing new experiments, and developing new therapeutic approaches.Author manuscript. Published in final edited form as: Proc Natl Acad Sci U S A. 2006 September 5; 103(36): 13474-13479.The final published version of this article is located at: www.pnas.org/cgi/doi/10.1073/pnas.0606053103NIH U56 CA113004; to David E. AxelrodR.A. was supported by National Science Foundation (NSF) Grant SES-0240852. D.E.A. was supported by NSF Grant IIS-0312953, National Institutes of Health (NIH) Grant U56 CA113004, and New Jersey Commission on Cancer Research Grant 1076-CCR-SO. K.J.P. is an American Cancer Society Clinical Research Professor and is supported by NIH Grants CA69568, CA102872, and CA093900.NIH CA69568; to Kenneth J. PientaNIH CA102872; to Kenneth J. PientaNIH CA093900; to Kenneth J. PientaNSF SES-0240852; to Robert AxelrodNJ Commission on Cancer Research 1076-CCR-SO; to David E. AxelrodAlso available in PubMed Central. PMCID: PMC155738
Frank Cooper
No full textFrank Cooper is the son of David and Anna Cooper from the Whiterocks area. He attended school at Alterra
The Arts Interview. Dr. David Pitt : The Truant Years, E. J. Pratt
No full textHost Fred Hollingshurst interviews Dr. David Pitt of Memorial University, who discusses the life and work of Newfoundland poet E. J. Pratt. Pitt is the author of E. J. Pratt: The Truant Years, 1881-1927
The Brain-Dead Organ Donor
No full textAddressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ‘storm’, that takes place during and following the induction of brain death, and how they impact metabolism. The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists.CONTENIDO: Introduction,
Dimitri Novitzky, David K. C. Cooper,
Pages 1-6 --
Historical Aspects of the Diagnosis of Death,
Félix Bacigalupo, Daniela A. Huerta Fernández,
Pages 7-11 --
The Determination of Brain Death,
Curtis M. Keller, Boris Chulpayev, Michael Hoffmann,
Pages 13-19 --
Legal Aspects of Brain Death and Organ Donorship,
Ricky T. Munoz, Mark D. Fox,
Pages 21-35 --
Ethical Issues in Organ Donation from Brain-Dead Donors,
Mark D. Fox, Ricky T. Munoz,
Pages 37-53 --
Pathophysiology of Brain Death in Small Animal Models,
Bernhard Floerchinger, Nicholas L. Tilney, Stefan G. Tullius,
Pages 55-64 --
Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models,
Dimitri Novitzky, Winston N. Wicomb, David K. C. Cooper,
Pages 65-90 --
The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease,
Lawrence E. Shapiro, Tatiana Baron,
Pages 91-105 --
The Inflammatory Response to Brain Death,
Anne Barklin, Christine Lodberg Hvas, Else Toennesen,
Pages 107-119 --
The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers,
Wayel Jassem, Susan V. Fuggle,
Pages 121-129 --
Brain Death-Induced Inflammation: Possible Role of the Cholinergic Anti-inflammatory Pathway,
Simone Hoeger, Benito A. Yard,
Pages 131-138 --
Innate Immunity and Injury During Brain Death: Opportunities for Intervention,
Marc A. Seelen, Henri G. D. Leuvenink, Rutger J. Ploeg,
Pages 139-145 --
Selection of the Brain-Dead Potential Organ Donor,
Kadiyala V. Ravindra, Keri E. Lunsford, Paul C. Kuo,
Pages 147-154 --
Infectious Disease Aspects of the Brain-Dead Potential Organ Donor,
Nicole M. Theodoropoulos, Michael G. Ison,
Pages 155-176 --
Malignancy in the Brain-Dead Organ Donor,
Michael A. Nalesnik, Ron Shapiro, Michael G. Ison,
Pages 177-189 --
Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor,
Dimitri Novitzky, Burcin Ekser, David K. C. Cooper,
Pages 191-207 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in the USA,
Demetrios Demetriades, Lydia Lam,
Pages 209-216 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Europe,
Gabriel J. Echeverri, Bruno G. Gridelli,
Pages 217-235 --
Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Australia,
Peter S. Macdonald, Anders E. M. Aneman, Deepak Bhonagiri, Daryl A. Jones, Gerry O’Callaghan, Helen I. Opdam et al.,
Pages 237-249 -- Management of the Brain-Dead Organ Donor: Perspectives of the Transplant Coordinator,
Nicole T. Farina, David K. C. Cooper,
Pages 251-261 --
Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors,
Michael J. Anstadt, Paul C. Kuo, Kadiyala V. Ravindra,
Pages 263-281 --
Impact of Brain Death on Storage of the Heart,
Winston N. Wicomb, David K. C. Cooper,
Pages 283-288 --
Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies,
Coney Bae, Anthony Watkins, Scot D. Henry, James V. Guarrera,
Pages 289-298 --
Functional Repair of Brain Death-Induced Injury,
Henri G. D. Leuvenink, Marc A. Seelen, Rutger J. Ploeg,
Pages 299-310 --
Functional Repair of Brain Death-Injured Donor Lungs,
Jonathan C. Yeung, Marcelo Cypel, Shaf Keshavjee,
Pages 311-320 --
Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor,
Dimitri Novitzky, David K. C. Cooper,
Pages 321-331 --
Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor,
Octavio E. Pajaro, James K. Kirklin,
Pages 333-341 --
Maximizing Utilization of the Potential Deceased Donor: The Challenge Continues,Eliezer Katz,Pages 343-35
Levothyroxine Treatment Increases Mortality in Patients with Heart Failure
No full textReview of: Einfeldt MN, Olsen AS, Kristensen SL, Khalid U, Faber J, Torp-Pedersen C, Gislason GH, Selmer C 2018 Long-term outcome in heart failure patients treated with levothyroxine: an observational nationwide cohort study. J Clin Endocrinol Metab. Epub 2018 Dec 4. PMID: 30517746
Observation of cooper pair splitting and andreev bound states in carbon nanotubes
No full textIn this thesis, we investigate Cooper pair splitting in double quantum dot devices made from carbon nanotubes. We present transport measurements in which the controlled splitting of Cooper pairs dominates the current through such a device, reaching unprecedented splitting efficiencies of up to 90%.
In another experiment we use Cooper pair splitting (and a related non-local transport processes) as a tool to investigate Andreev bound states. Andreev bound states are a key concept in mesoscopic superconductivity. They can form due to the penetration of Cooper pairs into a quantum dot, leading to a new type of energy level that differs drastically from conventional particle-in-a-box states
Data, R Code, and Output Supporting: Range Overlap between Mid-Continent and Eastern Sandhill Cranes revealed by GPS-tracking
No full textSee ReadMe text file for a comprehensive description of all uploaded files.This collection of files provide data, R code, and associated output supporting the article "Range Overlap between Mid-Continent and Eastern Sandhill Cranes revealed by GPS-tracking" in Wildlife Society Bulletin. We provide all necessary materials to reproduce the analysis of staging area overlap among GPS-marked Sandhill Cranes in Minnesota for the periods of August 1-October 1, 2015 and 2016. We captured and attached Global Positioning System-Global System for Mobile Communications (GPS-GSM) transmitters to 50 cranes in central Minnesota.U.S. Fish and Wildlife ServiceU.S. Geological SurveyMinnesota Cooperative Fish and Wildlife Research UnitMinnesota Environmental and Natural Resources Trust Fund as recommended by the Legislative-Citizen Commission on Minnesota Resources (LCCMR)Minnesota Department of Natural ResourcesWolfson, David W; Fieberg, John R; Lawrence, Jeff S; Cooper, Tom R; Andersen, David E. (2017). Data, R Code, and Output Supporting: Range Overlap between Mid-Continent and Eastern Sandhill Cranes revealed by GPS-tracking. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/D64P42
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