165,958 research outputs found
Engraved portrait of John Cook (bap. 1608, d. 1660)
No full textEngraved portrait of John Cook (bap. 1608, d. 1660). Line engraving after unknown artist. Two circular vignettes show Cook's execution at Tyburn and his head on a stake. Cook holds the book, 'Doctrina Libertinorum'. German title
Extrusion without a motor:a new take on the loop extrusion model of genome organization
No full textChromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is the only model to date which can explain this. However, the model requires a motor to generate the loops, and although cohesin is a strong candidate for the extruding factor, a suitable motor protein (or a motor activity in cohesin itself) has yet to be found. Here we explore a new hypothesis: that there is no motor, and thermal motion within the nucleus drives extrusion. Using theoretical modelling and computer simulations we ask whether such diffusive extrusion could feasibly generate loops. Our simulations uncover an interesting ratchet effect (where an osmotic pressure promotes loop growth), and suggest, by comparison to recent in vitro and in vivo measurements, that diffusive extrusion can in principle generate loops of the size observed in the data. Extra View on : C. A. Brackley, J. Johnson, D. Michieletto, A. N. Morozov, M. Nicodemi, P. R. Cook, and D. Marenduzzo "Non-equilibrium chromosome looping via molecular slip-links", Physical Review Letters 119 138101 (2017).</p
A review of the scholarship on Ebenezer Cook and a critical assessment of his works
No full textInterest in Ebenezer Cook has increased steadily, if slowly, since Moses Coit Tyler wrote an enthusiastic critique of The Sot-weed Factor in A History of American Literature, 1607-1765 in 1878. Much of that interest, however, has been little more than curiosity about a minor poet who remains an elusive literary figure of early eighteenth-century Maryland; even today, in spite of several recent assessments of his major poem s, relatively little critical attention has been given to the works of this often robust and witty author who wrote what are apparently the first American Hudibrastic poem, the first American mock-heroic, and the first belletristic work composed and published in the colonies south of Pennsylvania. Neither has there ever been a complete edition of the Cook canon, which consists, as far as we know, of three major poems--The Sotweed Factor (1708, revised extensively in 1731), Sotweed Redivivus (1730), and The History of Colonel Nathaniel Bacon's Rebellion in Virginia (1731)--and four elegies addressed to prominent Maryland citizens of Cook's day. This dissertation provides a comprehensive study of Ebenezer Cook that include critical analyses of all his known poems and transcriptions of the current canon based on first editions or earliest-known copies and manuscripts as w ell as historical background and commentary (much of Cook's poetry contains observations on the political, social, and economic issues of contemporary Maryland), bibliographical data, and a survey of Cook scholarship
Cook, A D, NX3821
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/378513Surname: COOK
Given Name(s) or Initials: A D
Military Service Number or Last Known Location: NX3821
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 5042192326
Item: [2016.0049.10807] "Cook, A D, NX3821
Letter from Cook, Uriah A. to Oblinger, Mattie V.
No full textLetter from Cook, Uriah A. to Oblinger, Mattie V. (Martha Virginia Thomas), 1844-188
Joann Herring/Joann Cook Oral History Interview
No full textJoAnn Cook, a lifelong resident of Carbon County, Utah, shares her experiences growing up in coal towns like Wellington and Rains, and later living in Price, with a period spent in Phoenix. She highlights her deep connection to the diverse landscape of Carbon County and the strong, inter-ethnic community that characterized the area due to the coal mines. Cook also recounts significant personal and professional challenges, including childhood hardship, perceived inequities, and a negative view of small-town politics, exemplified by a lawsuit against Price City over her beauty salon business license. She expresses a pessimistic outlook on the current state and future of Price, noting a decline in community participation, upkeep, and motivation among younger generations
Sr. Roseanne Cook Checking Blood Pressure
No full textSr. Roseanne Cook, CSJ, M,D. , checks a client's blood pressure at the health fair
Resenha de: Un caso de bigamia transatlántica, por Cook, A. P. & N. D. Cook (1992): Reflexões sobre o livro de A. P. Cook e N. D. Cook, Un caso de bigamia transatlántica
No full textReflections on the book written by A. P. Cook and N. D. Cook (1992) titled Un caso de bigamia transatlántica. Madrid, Anaya y Muchnik Editores. Reflexiones sobre el libro escrito por A. P. Cook y N. D. Cook (1992) titulado Un caso de bigamia transatlántica. Madrid, Anaya y Muchnik Editores. Reflexões sobre o livro de A. P. Cook e N. D. Cook (1992) intitulado Um caso de bigamia transatlântica. Madrid, Anaya e Muchnik Editores
Cook, D J, 214933
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/378477Surname: COOK
Given Name(s) or Initials: D J
Military Service Number or Last Known Location: 214933
Missing, Wounded and Prisoner of War Enquiry Card Index Number: V-1141192290
Item: [2016.0049.10771] "Cook, D J, 214933
Cook, D E, 43881
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/378476Surname: COOK
Given Name(s) or Initials: D E
Military Service Number or Last Known Location: 43881
Missing, Wounded and Prisoner of War Enquiry Card Index Number: SEA-2414192289
Item: [2016.0049.10770] "Cook, D E, 43881
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