88 research outputs found
Cuento de un cipote: Memoria, niñez y literatura en Siglo de o(g)ro de Manlio Argueta
No full textThis manuscript highlights the literary career of Manlio Argueta and comments on the Siglo de o(g)ro, where the author reflects his childhood and adolescence. This work studies the novelist aspect of the writer, used to denounce the social effervescence of those years, since El Salvador faces a civil war. In this novel, past times are redeemed, the author's category of memory is rescued.Este manuscrito destaca la trayectoria literaria de Manlio Argueta y comenta la Siglo de o(g)ro, donde el autor refracta su niñez y adolescencia. Con esta obra se estudia la faceta de novelista del escritor, usada para denunciar la efervescencia social de esos años, pues El Salvador enfrenta una guerra civil. En esta novela se redimen los tiempos pasados, se rescata la categoría de memoria en el autor
Probing the genomic landscape of human sexuality: a critical systematic review of the literature
No full textWhether human sexuality is the result of nature or nurture (or their complex interplay) represents a hot, often ideologically driven, and highly polarized debate with political and social ramifications, and with varying, conflicting findings reported in the literature. A number of heritability and behavioral genetics studies, including pedigree-based investigations, have hypothesized inheritance patterns of human sexual behaviors. On the other hand, in most twin, adoption, and nuclear family studies, it was not possible to disentangle between underlying genetic and shared environmental sources. Furthermore, these studies were not able to estimate the precise extent of genetic loading and to shed light both on the number and nature of the putative inherited factors, which remained largely unknown. Molecular genetic studies offer an unprecedented opportunity to overcome these drawbacks, by dissecting the molecular basis of human sexuality and allowing a better understanding of its biological roots if any. However, there exists no systematic review of the molecular genetics of human sexuality. Therefore, we undertook this critical systematic review and appraisal of the literature, with the ambitious aims of filling in these gaps of knowledge, especially from the methodological standpoint, and providing guidance to future studies. Sixteen studies were finally retained and overviewed in the present systematic review study. Seven studies were linkage studies, four studies utilized the candidate gene approach, and five studies were GWAS investigations. Limitations of these studies and implications for further research are discussed
Mental health for LGBTQI people: a policies' review
No full textThe mental health of lesbian, gay, bisexual, transgender, queer, intersexual (LGBTQI) individuals is significantly influenced by many factors such as difficulties in coming-out, poor acceptance, isolation and discrimination as well as minority-related stress. LGBTQI individuals, in fact, show a significant higher risk of mental health conditions, substance- use disorders and suicide. In addition, mental health services access may be difficult for personal and social barriers as well as a lack of adequate and specific mental health support. This review aims to assess and describe international policies, guidelines, position statements and recommendations regarding the promotion and protection of mental health rights for LGBTQI people. The search has been focussed on peer-reviewed papers, Governmental and Mental Health Association- Guidelines and Position Statements, Health Agencies - Guidelines and Position Statements (with a specific focus on mental health), LGBTQI Alliances and Foundations Publishing (with a specific focus on mental health). In addition, relevant international initiatives, and projects in the field of LGBTQI mental health will be described
The Century-Long Quest for the Gay Gene: Has the Elephant Given Birth to a Mouse? Towards Sexogenomics
No full textsj-docx-1-isp-10.1177_00207640231194478 – Supplemental material for Microaggression toward LGBTIQ people and implications for mental health: A systematic review
No full textSupplemental material, sj-docx-1-isp-10.1177_00207640231194478 for Microaggression toward LGBTIQ people and implications for mental health: A systematic review by Mattia Marchi, Antonio Travascio, Daniele Uberti, Edoardo De Micheli, Fabio Quartaroli, Giuseppe Laquatra, Pietro Grenzi, Luca Pingani, Silvia Ferrari, Andrea Fiorillo, Manlio Converti, Federica Pinna, Francesco Amaddeo, Antonio Ventriglio, Massimo Mirandola and Gian M Galeazzi in International Journal of Social Psychiatry</p
Investigating and Practicing Orthopedics at the Intersection of Sex and Gender: Understanding the Physiological Basis, Pathology, and Treatment Response of Orthopedic Conditions by Adopting a Gender Lens: A Narrative Overview
No full textIn the biomedical field, the differentiation between sex and gender is crucial for enhancing
the understanding of human health and personalizing medical treatments, particularly within the
domain of orthopedics. This distinction, often overlooked or misunderstood, is vital for dissecting and
treating musculoskeletal conditions effectively. This review delves into the sex- and gender-specific
physiology of bones, cartilage, ligaments, and tendons, highlighting how hormonal differences
impact the musculoskeletal system’s structure and function, and exploring the physiopathology of
orthopedic conditions from an epidemiological, molecular, and clinical perspective, shedding light
on the discrepancies in disease manifestation across sexes. Examples such as the higher rates of
deformities (adolescent idiopathic and adult degenerative scoliosis and hallux valgus) in females and
osteoporosis in postmenopausal women illustrate the critical role of sex and gender in orthopedic
health. Additionally, the review addresses the morbidity–mortality paradox, where women, despite
appearing less healthy on frailty indexes, show lower mortality rates, highlighting the complex
interplay between biological and social determinants of health. Injuries and chronic orthopedic
conditions such osteoarthritis exhibit gender- and sex-specific prevalence and progression patterns,
necessitating a nuanced approach to treatment that considers these differences to optimize outcomes.
Moreover, the review underscores the importance of recognizing the unique needs of sexual minority
and gender-diverse individuals in orthopedic care, emphasizing the impact of gender-affirming
hormone therapy on aspects like bone health and perioperative risks. To foster advancements in sexand
gender-specific orthopedics, we advocate for the strategic disaggregation of data by sex and
gender and the inclusion of “Sexual Orientation and Gender Identity” (SOGI) data in research and
clinical practice. Such measures can enrich clinical insights, ensure tailored patient care, and promote
inclusivity within orthopedic treatments, ultimately enhancing the precision and effectiveness of care
for diverse patient populations. Integrating sex and gender considerations into orthopedic research and practice is paramount for addressing the complex and varied needs of patients. By embracing
this comprehensive approach, orthopedic medicine can move towards more personalized, effective,
and inclusive treatment strategies, thereby improving patient outcomes and advancing the field
La polpa e l'osso: scritti di Manlio Rossi Doria su agricoltura risorse naturali e ambiente
No full textThe article is the introduction to the volume edited by the author with the same title on the occasion of the centennial anniversary of Manlio Rossi-Doria. The volume is a collection of selected writings published between 1929 and 1986 divided in four thematic sections: agronomic modernization, land amelioration, natural disasters and human action, ecology and energy. Prevailing contents by sections are as follows:first, land management, pasture improvement, soil protection, upland and lowland integration; second, land reclamation and land tenure; third, natural and man made disasters and related policies; fourth, ecology, energy sources, including nuclear, and related policy issues. After presenting the structure of the selection, an overview of selected writings emphasizes the continuity of Manlio Rossi-Doria committment with agriculture environment natural resources and related policie
Protocolli conservativi nell'integrazione delle lacune murarie di ponte Nugent a Capua.
No full textThis study proposes a multidisciplinary framework for optimizing the timing and the type of maintenance, based on a methodology developed to update lifetime inspection and repair of brick structures involving a decision tree analysis. Architectural heritage and civil engineering structures are designed to serve public instances, performing safely for decades. In spite of that, no matter how well they are designed, all these structures are going to deteriorate over time. Thus, maintenance strategies should promote solutions that are directed towards preservation and conservation by relying on the existing structural capacity and give preference to stabilization rather than substitution or replacement. In this context, the paper has been proactive in identifying the significance of brick-masonry arch bridges; hence, once the cultural impact has been determined, the next logical step in dealing with these historic structures was to develop a treatment/management plan. The methodology is illustrated by the first results of the project entitled “Improving assessment of Nugent bridge in Capua”, organized by the author, to develop and provide tools that help optimising the life-cycle management of brick-masonry arch bridges, preserving both the physical structure and the historic authenticity, while promoting an effective exchange of good practice between the railway administrations
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