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Variabilità della capacità diagnostica del “Glaucoma Probability Score” e delle formule discrminanti a seconda della grandezza della papilla ottica.
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Effect of Refractive Correction on the Accuracy of Frequency-doubling Technology Matrix.
No full textPURPOSE:: To investigate the effect of refractive correction on the reliability and accuracy of frequency-doubling technology (FDT) Matrix examinations. METHODS:: Forty-eight eyes of healthy people were submitted to the FDT Matrix 30/2 threshold program. They had experience in perimetry, normal eye examination, and negative history for glaucoma and/or neurological diseases. The subjects were randomized into groups A (24 subjects) and B (24 subjects). The FDT Matrix 30/2 examinations were carried out in 3 different sessions. At the first session, groups A and B underwent the examinations with their best refractive correction. In the second session, group A underwent the FDT 30/2 examination with best refractive correction and the group B without it. In the third session, the groups were matched and followed the same protocol. The perimetric and reliability indexes and the time of examination with or without correction were considered. The Student t test was used when the distribution of the data was normal, whereas Mann-Whitney when the distribution of the data was not normal. After a Bonferroni correction, a P value <0.001 was considered as statistically significant. RESULTS:: Mean deviation reduced statistically significantly when refractive correction was used (-2.65±3.71 vs. -1.41±3.51 dB; P<0.006). All the other perimetric indexes and data considered did not change significantly when the subjects did the examination with or without the refractive correction. CONCLUSIONS:: The statistically significant reduction of mean deviation obtained with corrective lens showed that a better general accuracy and reliability of FDT responses was obtained with refractive correction. Pattern standard deviation constancy with or without correction confirmed that a localized defect is the first sign of visual field defect and that the absence of differences of pattern standard deviation between the 2 sessions is related to the absence of pathologic conditions in the eyes studied. Finally, as FDT Matrix is less influenced by other nonconventional perimetric techniques by refractive errors, the use of corrective lens is advisable to improve the accuracy and reliability of the results obtained and to optimize their performance
Moorfield regression analysis versus retinal nerve fiber layer in glaucoma and ocular hypertension
No full textPurpose: To evaluate the agreement
between Moorfield Regression
Analysis (MRA) and peripapillary
retinal nerve fibers layer thickness.
Methods: 54 eyes with normal VF
and 18 with early VF damage were
classified as ocular hypertension or
early primary open angle glaucoma
(POAG) and were included in the
study: All the subjects performed
achromatic 30° visual field (VF) by
Octopus Program G1X dynamic
strategy and were imaged by HRT 3
and I-Vue OCT. Sectorial and global
MRA and OCT parameters were
used for the analysis. Kappa statistic
was used to assess the agreement
between methods.
Results: A significant agreement
between I-Vue OCT and MRA a
good agreement was shown in the
supero-nasal (κ 0.656) and nasal
(κ 0.627) quadrants followed by the
supero-temporal (κ 0.602) and inferotemporal
(κ 0.586) sectors in all the
eyes studied.
Conclusion: Our results suggest that
the measurements of the ganglion
cells by HRT 3 and I-Vue OCT are not
interchangeable
Valutazione del grado di correlazione tra la MRA (moorfield regression Analysis), il GPS (Glaucoma Probability Score) dell’ HRT III e L’ONH glaucoma analysis dell’OCT i-Vue.
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Evaluation of agreement between HRT III and iVue OCT in Glaucoma and Ocular Hypertension patients.
No full textPurpose. To determine the agreement between Moorfields Regression Analysis (MRA), Glaucoma Probability Score (GPS) of Heidelberg retinal tomograph (HRT III), and peripapillary nerve fibers thickness by iVue Optical Coherence Tomography (OCT). Methods. 72 eyes with ocular hypertension or primary open angle glaucoma (POAG) were included in the study: 54 eyes had normal visual fields (VF) and 18 had VF damage. All subjects performed achromatic 30° VF by Octopus Program G1X dynamic strategy and were imaged with HRT III and iVue OCT. Sectorial and global MRA, GPS, and OCT parameters were used for the analysis. Kappa statistic was used to assess the agreement between methods. Results. A significant agreement between iVue OCT and GPS for the inferotemporal quadrant (κ: 0.555) was found in patients with abnormal VF. A good overall agreement between GPS and MRA was found in all the eyes tested (κ: 0.511). A good agreement between iVue OCT and MRA was shown in the superonasal (κ: 0.656) and nasal (κ: 0.627) quadrants followed by the superotemporal (κ: 0.602) and inferotemporal (κ: 0.586) sectors in all the studied eyes. Conclusion. The highest percentages of agreement were found per quadrant of the MRA and the iVue OCT confirming that in glaucoma damage starts from the temporal hemiretina
Valutazione della concordanza tra la Moorfield Regression Analysis (MRA), il Glaucoma Probability Score (GPS) dell'HRT III e L'ONH glacoma analysis dell'OCT i-Vue
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