2,465 research outputs found

    No. 617 Stuart Ruckman

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    Transcript (12, 40 pages) of two interviews by Matt Driscoll with Stuart Ruckman on April 9, 2010, and July 7, 2011Ruckman (b. 1966) was born in Salt Lake City, Utah. Stuart shares how his family, particularly his father, played a significant role in introducing him to the outdoors. Some of his initial explorations included a hike to the top of Mount Olympus when he was five years old, backpacking trips in the Wasatch and Uinta Mountains, and a successful summit attempt on the Grand Teton when he was twelve. Stuart discovered technical rock climbing due to the influence of his older brother Bret, five years Stuart\u27s senior. Bret learned under Dennis Turville, a well-respected Salt Lake climbing instructor. Stuart shares his observations on the Salt Lake climbing community of the late 1970s and 1980s, noting the intimacy of the community, while also pointing out the significant influence of a handful of climbers, including Merrill Bitter, Les Ellison, and Brian Smoot. He briefly describes the proliferation of new-route development in the Wasatch during his first decade in climbing. In collaboration with his brother Bret, Stuart published comprehensive guidebooks on climbing in the Wasatch Mountains. Stuart\u27s contributions as a first-ascensionist and co-author of Rock Climbing the Wasatch Range attest to his lasting impact on Utah climbing. Interview is part of the Outdoor Recreation History Project. Interviewer: Matt Driscol

    Redemption in the work of Francis Stuart

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    The idea of redemption is central to an understanding of the work of Francis Stuart. Through an examination of its development and expression, it is possible to demonstrate the integrity of his work and its distinctive qualities. Such a demonstration is necessary because Stuart's writing has been subjected to comparatively little scholarly inquiry, although reviews of his work, especially that produced since 1949, suggest that it is impressive and important. First, a general background to Stuart's work, a discussion of the special problems associated with reading it, and a summary of his corpus is provided. This indicates that the idea of redemption is important to his earliest writing. The state of redemption is shown to be a necessary apotheosis for Stuart's outcast heroes; it involves spiritual suffering through which may be found a sense of reintegration and a higher reality. This is expressed through interrelated themes such as those of gambler, artist and ordinary man; mystic and criminal; sacred and profane love; and spirituality and the mundane. The nature of the redemptive experience is further elaborated by distinctive, complex motifs, especially the hare, the ark and the woman-Christ. Their recurrence provides an important element in the unity of Stuart's work. Because Stuart's idea of the outcast raises important biographical questions, an examination of the relationship between Stuart's life and his work is made. Finally, the way in which the idea of redemption exists in the language structures of Stuart's novels is examined, with especial reference to his most recent work, The High Consistory. The thesis shows that the development of the these of redemption demonstrates the integrity of Stuart's work

    sj-docx-1-wso-10.1177_17474930231216339 – Supplemental material for Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial

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    Supplemental material, sj-docx-1-wso-10.1177_17474930231216339 for Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial by Pargol Balali, Robert G Hart, Eric E Smith, Feryal Saad, Pablo Colorado, Robin Lemmens, Gian Marco De Marchis, Valeria Caso, Lizhen Xu, Laura Heenan, Stuart J Connolly, Hardi Mundl and Ashkan Shoamanesh in International Journal of Stroke</p

    John Stuart Mill’s projected science of society: 1827-1848

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    The purpose of the thesis is to examine John Stuart Mill’s political thought from about 1827 to 1848 as an exercise in intellectual history. It focuses, first, on Mill’s view, formulated by the late 1830s, that contemporary society was ‘civilized’, and second, on his project of a science of society, which he aspired to develop in the late 1830s and early 1840s. By the late 1830s, Mill came to the view that his contemporary society was a ‘commercial society or civilization’, dominated by the middle, commercial class. The first part of my thesis, constituted by Chapters 2-4, discusses the way in which Mill formed his notion of civilization, and what he meant by the term ‘civilization’. Mill paid attention to the implications of the rise of the middle class, and regarded such phenomena of contemporary society as the corruption of the commercial spirit and excessive social conformity as an inevitable consequence of the rise of the middle class. The second part of the thesis, constituted by Chapters 5-9, examines Mill’s projected science of society. In the late 1830s and early 1840s, Mill attempted to develop a new science of society whose subject-matter was the nature and prospects of commercial, civilized society. This aspiration culminated in A System of Logic, published in 1843. In examining Mill’s projected science, I pay particular attention to the fact that he conceived new sciences of history and of the formation of character, both of which were indispensable in his project, although he failed to give a complete account of these sciences. My thesis shows that the implications of his interest both in history and in the formation of character are more significant than Mill scholars have assumed

    Trade bookbinding in the British Isles, 1660-1800 by Stuart Bennett

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    reviewA review of "Trade Bookbinding in the British Isles, 1660-1800" by Stuart Bennett

    Reading Stuart Elden’s The Birth of Territory

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    The Birth of Territory is an outstanding scholarly achievement, a book ‘of remarkable depth and breadth’, as noted by Alec Murphy in his comment, a book that already promises to become a ‘classic’ in geography, together with very few others published in the past decades. But Elden's book is also a difficult one to position within mainstream human geography. Its genealogical engagement with multiple sources/texts in various historical and linguistic contexts is far reaching, and it has very few precedents in the discipline—since it is deliberately inspired by the Cambridge school of contextual history, and the German tradition of Begriffsgeschichte, conceptual history. The Birth of Territory is also methodologically challenging, as its account of territory is carved out of a clear selection of ‘presences and absences’ operated by the author that, like all work of this kind, is open to criticism in relation to the strategies of inclusion/exclusion (of texts, concepts, people) adopted. What follows is a brief account of an Author meets Critics panel on The Birth of Territory held at the AAG Conference held in Tampa in April 2014

    Social Behavior and Meningococcal Carriage in British Teenagers

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    Understanding predisposing factors for meningococcal carriage may identify targets for public health interventions. Before mass vaccination with meningococcal group C conjugate vaccine began in autumn 1999, we took pharyngeal swabs from ?14,000 UK teenagers and collected information on potential risk factors. Neisseria meningitidis was cultured from 2,319 (16.7%) of 13,919 swabs. In multivariable analysis, attendance at pubs/clubs, intimate kissing, and cigarette smoking were each independently and strongly associated with increased risk for meningococcal carriage (p&lt;0.001). Carriage in those with none of these risk factors was 7.8%, compared to 32.8% in those with all 3. Passive smoking was also linked to higher risk for carriage, but age, sex, social deprivation, home crowding, or school characteristics had little or no effect. Social behavior, rather than age or sex, can explain the higher frequency of meningococcal carriage among teenagers. A ban on smoking in public places may reduce risk for transmission

    DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire

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    The majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire

    The Law of Healthcare Administration

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    Healthcare leaders must navigate a complex and constantly evolving legal environment. The Law of Healthcare Administration provides a comprehensive and practical overview of healthcare law and its role in the management of healthcare organizations.The tenth edition of this classic text explores substantial shifts in the legal landscape, including the effects of the COVID pandemic, the Dobbs v. Jackson Women’s Health Organization abortion rights decision, and Biden-era legislative and regulatory developments. J. Stuart Showalter and new co-author Sallie Thieme Sanford provide a broad perspective on a wide range of healthcare justice issues, using inclusive language and incorporating examples that involve various types of healthcare providers.https://digitalcommons.law.uw.edu/faculty-books/1081/thumbnail.jp
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