752 research outputs found

    Messina, città nobilissima : descritta in VIII. libri /

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    Includes index.Engraved t.p. vignette (allegory of Messina). Full-page engraved port. of author, leaf [4]v. Woodcut head- and tail-pieces, decorated initials."Nella quale si contengono i suoi primi fondatori, sito, edificij sacri, & publichi, porto, fortezze, strade, piazze, fonti, venute di principi, funerali, feste sacre, secolari, vsi, armamento, & della dignità sacra & secolare, con altre cose notabili & degne di memoria."Mode of access: Internet.Copy 1 signed on front free endpaper recto by Giacomo Soranzo, and dated 1728.Binding, c. 1: later heavy paper. Page edges blue. Binding, c. 2: later vellum. Author, title & date written at head of spine. Remains of 2 pairs of ties at foredge

    The wronskian and its derivatives

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    Articolo testo di una conferenza tenuta presso l'Accademia Peloritana dei Pericolanti (Messina

    Coronavirus Crisis and Its Effects on the Fishery Value Chain

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    the fishery and aquaculture sector has been particularly hard hit by the market disruption generated by a significant drop in demand, ensuing from the COVID-19 outbreak. The closure of sales venues, markets, outlets, and distribution channels has seen prices and volumes drop substantially. The drop in demand and prices, combined with the supply chain’s vulnerability and complexity, has made fishing fleets and seafood production loss-making operations

    Declaration of Intention for Pietro Tomasino

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    Declaration of Intention to become a citizen of the United States, as filled out and signed by Pietro Tomasino. Applicant lists himself as a 37 year old baker residing in Hammonton, New Jersey, born in Messina, Italy on 13 May 1879, who sailed on the US bound vessel Tourumina. Wife's name is Concetta. Declaration submitted and sworn May 9, 1912

    Maestri dei codici miniati normanni di Messina

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    Si delinea l'attività dei miniatori attivi a Messina in età tardo-normann

    Sub-lethal Doses of Polybrominated Diphenyl Ethers, in Vitro, Promote Oxidative Stress and Modulate Molecular Markers Related to Cell Cycle, Antioxidant Balance and Cellular Energy Management

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    In the present study, we evaluated the effects of different concentrations of the polybrominated diphenyl ethers (PBDEs) BDE-209, BDE-47 and BDE-99, on the vitality and oxidative stress of a HS-68 human cell culture exposed to the compounds for three days. The results showed that for this exposure time, only the highest concentrations produced a significant vitality reduction and oxidative stress induction (p < 0.05), measured as reactive oxygen species (ROS). Subsequently, in order to verify the effects of sub-lethal doses, cells were exposed for a longer time and data collected, after 12 and 20 days, to study ROS production and some molecular markers related to cell cycle and stress (p53, pRB, PARP, c-Jun and c-Fos), antioxidant status and proliferation (ERK, c-Jun and c-Fos), energy balance (NRF2, AMPK, HIF). Most of the biomarkers were influenced by the treatments, indicating that sub-lethal doses of PBDEs, for longer time, can enhance the production of ROS, altering the energetic metabolism, cell cycle and antioxidant balance, determining possible negative effects on the cell proliferation equilibrium

    On the performance of advanced three-dimensional models for cylindrically bent plates subjected to arbitrary boundary conditions

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    Based on recent researches (e.g. [1–3]) aimed at approaching the three-dimensional dynamical values (natural frequencies and mode shapes) of multilayered plates subjected to classical although arbitrary boundary conditions, the interest of the present communication is based on the attempt to test the pres- ent simple analytical approach while preserving the accuracy of the results within the frame of the exist- ing modern calculators. Such an attempt has been previously pursued by the present author through the classical theorem of virtual displacements along with the adoption of the global piecewise smooth func- tions (GPSFs) [4]; as is shown by Messina and Rollo [2] and Messina [3], such a formalization has allowed one to deal with a multilayered architecture as if the plates were made up of a single layer sub- jected to classical arbitrary boundary conditions with, these latter, even dealt with through only three distinct functional bases. The fact that any explicit continuity conditions of the relevant interfacial stress components are not explicitly introduced could be worth mentioning. The above-mentioned analyses left, however, open questions; indeed, Messina [3] noticed certain boundary conditions as mainly respon- sible for a low convergence of eigenvalues to the expected exact three-dimensional counterparts. After investigating the mentioned influence of boundary conditions [3], this writer became aware of static analyses of possible relevant interest. In particular, this writer noticed with extreme interest the paper by Vel and Batra [5] to which the attention of this note is essentially addressed. Vel and Batra [5] analysed the generalized plane strain deformations from a static point of view and by using the Eshelby– Stroh formalism. In spite of the different nature of the problem (static in [5], dynamic in [1,3]) we must accept the fact that a possible slack convergence at exact values in a static analysis is a particular aspect of its dynamic counterpart and vice versa. Therefore, this author discusses the performance of the Eshelby–Stroh formalism, illustrated by Vel and Batra [5], in comparison to the capability of an analytical model to deal with multilayered plates as if they were made up of a single layer architecture [1,3] within the frame of static deformations. Interestingly the comparison will show how sometimes the explicit introduction of the required natural boundary conditions can reduce the accuracy of the results. Moreover, it is shown how the GPSFs bring remarkable benefits when used to model multilayered plates; the benefits can even increase when the GPSFs are used in multiple dimensions rather than only through the thickness of the plate. In passing, and finally, the present comparison shows a slight disagreement with Vel and Batra [5] for few transver- sal stress component distributions; this slight disagreement, however, is definitely of extremely minor importance when compared to the clean and helpful frame offered by the analysis of [5]

    Lipid composition and metabolism of European sea bass (Dicentrarchus labrax L.) fed diets containing wheat gluten and legumes meals as substitutes for fish meal

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    The role of dietary protein source on growth performance and lipid metabolism in European sea bass (Dicentrarchus labrax) was investigated, by the evaluation of fat content in different tissues, plasma metabolites, liver lipogenic activity and fatty acid composition of dorsal muscle tissue.Five isonitrogenous (490gkg-1crude protein dry-matter basis) and isolipidic (170gkg-1lipid dry-matter basis) diets with graded levels of wheat gluten, soybean and pea meal in substitution of fish meal were evaluated in European sea bass (initial body weight 23.9±0.1) for 96days. There was a significant difference (p<0.05) in dorsal muscle and liver lipid contents. Plasma glucose and cholesterol levels decreased significantly (p<0.05) as diet included soybean and wheat gluten meal (p<0.05). The composition of fatty acids in muscle triacylglycerols and phospholipids was affected by vegetable sources as n-6 PUFA percentage was significantly increased and n-3 PUFA percentage was significantly decreased (p<0.05), without modifying EPA/DHA ratio, when wheat gluten and pea meal were included in the diet. The results confirm that the quality and quantity of vegetable protein source could affect lipid metabolism and lipid content in the dorsal muscle of the European sea bass and suggest the possibility of manipulation of the diet for commercial purpose

    Biotechnological Applications for the Sustainable Use of Marine By-products: In Vitro Antioxidant and Pro-apoptotic Effects of Astaxanthin Extracted with Supercritical CO2 from Parapeneus longirostris

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    In this study, the carotenoid astaxanthin was obtained by supercritical fluid extraction (SFE) from shrimp by-products (SBP). Its bioactive properties were evaluated in vitro in human normal and cancerous cells lines. The antioxidant activity of the extracted astaxanthin of the SFE fraction (ASTA) was tested in fibroblast cells (HS-68), by inducing oxidative stress and by evaluating the protective effect of the pre-treatment with different levels of ASTA against toxicity. The anti-proliferative activity was evaluated in hepatoma cells (HEP-G2), treated with increased concentrations of ASTA and measuring the effects on vitality and on some biomolecular markers related to oxidative stress, cell cycle, and apoptosis. It was found that pre-treating normal fibroblast cells with ASTA resulted in a marked increase in cell viability in a dose-dependent manner (P < 0.05) attesting its antioxidant power; in cancer cell line, increased concentrations of ASTA caused a time-dose-dependent decrease in the vitality, attesting its anti-proliferative activity (P < 0.05). The increased levels of the protein p-53 and the reduced levels of the proteins c-Jun and c-Fos at higher concentrations of ASTA, as well as, suggest the pro-apoptotic and anti-cancerous effects that this extract has on hepatocellular carcinomas, confirmed also by caspase-3 activation. These findings suggest biotechnological utilisation of marine by-products for nutraceutical and pharmaceutical applications avoiding the employment of organic solvents for extraction
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