3 research outputs found

    Diferencias en la composicin corporal y nutricional entre jóvenes tenistas de la Rafa Nadal Academy y el Club de Tenis Valle de Aridane

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    Concepcion Vaquer, Daniel; director de proyecto: Strunk Pomar, Robert2023-2024Máster de Formación Permanente en Nutrición Deportiva y EntrenamientoFacultad de Ciencias de la Salu

    Interaction of Wnt3a, Msgn1 and Tbx6 in neural versus paraxial mesoderm lineage commitment and paraxial mesoderm differentiation in the mouse embryo

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    AbstractParaxial mesoderm is the tissue which gives rise to the skeletal muscles and vertebral column of the body. A gene regulatory network operating in the formation of paraxial mesoderm has been described. This network hinges on three key factors, Wnt3a, Msgn1 and Tbx6, each of which is critical for paraxial mesoderm formation, since absence of any one of these factors results in complete absence of posterior somites. In this study we determined and compared the spatial and temporal patterns of expression of Wnt3a, Msgn1 and Tbx6 at a time when paraxial mesoderm is being formed. Then, we performed a comparative characterization of mutants in Wnt3a, Msgn1 and Tbx6. To determine the epistatic relationship between these three genes, and begin to decipher the complex interplay between them, we analyzed double mutant embryos and compared their phenotypes to the single mutants. Through the analysis of molecular markers in mutants, our data support the bipotential nature of the progenitor cells for paraxial mesoderm and establish regulatory relationships between genes involved in the choice between neural and mesoderm fates

    The Common Frame of Reference in Europe

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    Discusses the origins of the Draft Common Frame of Reference and assesses the need for further work in particular areas, taking as an example the subject of restitutionary damages for non-performance of a contract. Also assesses the possible relevance of the DCFR in work on African legal unity
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