86,559 research outputs found

    L’interazione tra sistema economico e sistema politico, l’influenza della distribuzione del reddito sulla crescita economica

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    Il risultato di maggior rilievo di questo lavoro è quello di essere riusciti a fondare una struttura logica che consenta di interpretare in modo agevole il complesso processo di interazione tra sistema politico e sistema economico; soprattutto, una struttura logica che integra in modo originale gli approcci teorici delle funzioni di influenza, delle funzioni di interesse e neokaleckiano, che fino ad ora erano stati considerati alternativi oppure non erano mai stati messi in relazione gli uni con gli altri. Nell’ambito di questa struttura logica è importante il concetto di gruppo di pressione, in quanto si ipotizza che la politica economica sia condizionata dall’attività di lobbying. Il principale obiettivo è quello di analizzare le conseguenze per la crescita economica di scelte politiche frutto di processi di lobbying che trovano le loro motivazioni nella distribuzione del reddito; in questo caso, l’impiego dell’approccio teorico neokaleckiano riflette la necessità di studiare le dinamiche economiche come risultanza delle dinamiche assunte dalla domanda effettiva. Alla luce di queste osservazioni si evidenzia che le diverse ipotesi che caratterizzano il sistema economico ed il sistema politico devono essere interpretate, più che come limitazioni dell’analisi, come il nocciolo di futuri indirizzi di ricerca che potranno privilegiare l’esame di aspetti dell’uno oppure dell’altro sistema. In definitiva, questo lavoro vuole fornire una serie di nuovi strumenti, sia logici che analitici, che consentano di interpretare in modo più agevole la realtà; realtà di cui si è esaminato un aspetto cruciale: l’influenza della distribuzione del reddito sulla crescita economica mediata dal processo di interazione tra sistema economico e sistema politico

    Immunotherapy in non-small-cell lung cancer: a bridge between research and clinical practice.

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    Lung cancer has been historically considered a poorly immunogenic disease because of the few evidence of immune responses in affected patients and the limited efficacy of immunomodulating strategies. Recent understanding of the molecular mechanisms leading to cancer immune evasion has allowed the development of a new class of drugs called immune checkpoint inhibitors, which reactivate host responses with outstanding clinical benefits in a portion of patients with non-small-cell lung cancer. In this review, we briefly summarize the basis of immunogenicity and immune escape of cancer, with specific focus on non-small-cell lung cancer, mechanisms underlying immune checkpoint inhibitors efficacy and the most updated results on potential biomarkers, with the final aim of defining current unmet needs of immunotherapy in clinical practice

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Monetary policy and financial stability in the Economic and Monetary Union

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    Following the financial crisis, a new theoretical framework has emerged, in which monetary policy aims at price stability and macro-prudential policy aims at financial stability. In 2014, the European institutions established the Single Supervisory Mechanism (SSM) to pursue the objective of financial stability. The new institutional arrangement provides for micro-prudential policy under the direct control of the ECB and macro-prudential policy under the responsibility of NCAs and the supervision of the ECB. The essay presents a literature review and a simple analytical model to assess this new institu-tional design. Despite a still incomplete reform process, as the decision-making process lacks total transparency and the regulatory field is not levelled, the literature review supports the view that the SSM promotes financial stability in the Euro area. According to our model, we positively assess the new institutional framework: an increase in the efficiency of prudential policies to face financial risks allows the ECB to pursue the objective of financial stability without compromising the goal of output stability

    Productive Public Expenditure in a New Economic Geography Model

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    We assess whether and how differences in productive public expenditure impacts on industrial location. Since productive public expenditure and taxation affect in opposite direction industrial location, it is not straightforward that following an increase in productive public expenditure in a region, that region will necessarily enjoy stronger agglomeration. As a major contribution to the literature, we consider jointly two effects arising from public policy: the demand effect and the productivity effect. The interplay of these two effects determines the final impact on the spatial distribution of firms. The result is influenced by the proportion in which tax payers of the two regions contribute to the financing of public expenditure.economic geography; public expenditure, footloose capital

    [Newspaper Clipping: Author Claims Evidence of Second JFK Assassin #1]

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    Newspaper article titled "Author Claims Evidence of Second JFK Assassin." The article states that author Richard J. Whalen concluded "that there is circumstantial evidence to support the theory of a second assassin in the shooting of President John F. Kennedy.

    Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation

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    The desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters

    John F. Kennedy telegram to Roosevelt

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    Jersey Homesteads (later the Borough of Roosevelt) was established in the 1930s as an agro-industrial cooperative community. It was established specifically for urban Jewish garment workers, many of whom had emigrated from Europe. President John F. Kennedy sent a telegram to the citizens of Roosevelt, New Jersey, apologizing for not being able to attend the memorial dedication in honor of former President Franklin Delano Roosevelt. (Jersey Homesteads became Roosevelt in 1945 in honor of the president.) President Kennedy expressed his gratitude to the people of Roosevelt for constructing the memorial, and commented that it will serve as a constant reminder of Roosevelt's good works
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