1,721,147 research outputs found

    The role of biotransformation in the estrogenicity of xenobiotics

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor

    Drug induced liver injury: Assessment of inter-individual variation in the balance of bioactivation and inactivation as risk factor

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor]Vos, J.C. [Copromotor

    Glutathione-S-transferases: tools and targets for characterization of chemically reactive drug metabolites

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor

    Drug Biotransformation Enzyme Interactions Studies with Curcumin, Curcumin analogues and other Plant-derived Components

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor

    Bioactivation of Drugs by Cytochromes P450 : New Tools and Concepts for the Characterization of Reactive Metabolites of Drugs

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor

    Cytochrome P450 BM3 as versatile biocatalytic tool in drug development

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor

    Interplay between phase I and phase II biotransformation of drugs: In vitro approaches to study the formation and fate of reactive metabolites

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    Vermeulen, N.P.E. [Promotor]Vos, J.C. [Copromotor]Commandeur, J.N.M. [Copromotor

    Characterization of biotransformation enzymes involved in Adverse Drug Reactions: The cases of Nevirapine, Ticlopidine, Flucloxacillin and Clozapine

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    Vermeulen, N.P.E. [Promotor]Vos, J.C. [Copromotor]Commandeur, J.N.M. [Copromotor

    Role of genetic polymorphisms of drug metabolising enzymes in idiosyncratic drug reactions In vitro to in vivo translation

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    Vermeulen, N.P.E. [Promotor]Commandeur, J.N.M. [Copromotor
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