15,358 research outputs found

    Annual John M. Perkins Lecture

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    John Perkins returns to the SPU campus for the seventh annual John M. Perkins Lecture. One of the leading evangelical voices to come out of the American civil rights movement, Perkins is an internationally known author, speaker, and teacher. He has received honorary doctorates from several U.S. universities, including Seattle Pacific University

    Letter from Rev. John M. Yamazaki, March 27, 1945

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    Correspondence from Reverend John M. Yamazaki to "friends" regarding "resettlement" to the west coast.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications

    John M. Perkins Center Twelfth Annual Lecture

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    Each year our university has the privilege of hearing Dr. John Perkins speak in chapel as part of the John Perkins Lecture series. Dr. Perkins helped launch the John Perkins Center at SPU, is distinguished visiting professor at SPU, and is the co-founder of the Christian Community Development Association. He is the recipient of numerous honorary doctorates and awards, and the author of several books including his most recent work, Dream With Me

    John M. Perkins Center Ninth Annual Lecture

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    John Perkins, one of the leading evangelical voices to come out of the American civil rights movement, returns to SPU for his annual lecture. An internationally known author, speaker, and teacher, he is the co-founder of SPU\u27s John Perkins Center

    There and Back piece recounting author John McDonald\u27s first trip to Lewiston-

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    There and Back piece recounting author John McDonald\u27s first trip to Lewiston-Auburn. Driving a 1953 two-tone Chevy Powerglide, McDonald and his cousin visited the twin cities to hear John F. Kennedy speak as part of his 1960 presidential campaign against Richard M. Nixon

    Modelling chase-and-run migration in heterogeneous populations

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    Cell migration is crucial for many physiological and pathological processes. During embryogenesis, neural crest cells undergo coordinated epithelial to mesenchymal transformations and migrate towards various forming organs. Here we develop a computational model to understand how mutual interactions between migrating neural crest cells (NCs) and the surrounding population of placode cells (PCs) generate coordinated migration. According to experimental findings,we implement aminimal set of hypotheses, based on a coupling between chemotactic movement of NCs in response to a placode-secreted chemoattractant (Sdf1) and repulsion induced from contact inhibition of locomotion (CIL), triggered by heterotypic NC–PC contacts. This basic set of assumptions is able to semi-quantitatively recapitulate experimental observations of the characteristic multispecies phenomenon of “chase-and-run”, where the colony of NCs chases an evasive PC aggregate. The model further reproduces a number of in vitro manipulations, including full or partial disruption of NC chemotactic migration and selected mechanisms coordinating the CIL phenomenon. Finally, we provide various predictions based on altering other key components of the model mechanisms

    Author John M. Barry Tells the Story of Early America’s Emerging Ideals Through Roger Williams

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    Bestselling author and historian John M. Barry revealed the story behind University namesake and the founder of Rhode Island

    John M. Killits, Toledo, Ohio [approximately 1930]

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    Photograph of John M. Killits, a judge and author. The photo dates around June 1930. Terms associated with the photograph are: Killits, John M. | Judges | Judges--1930-1940. | authors | Suits(Clothing) | Eyeglasses | Eyeglasses--1930-1940. | Mustaches | Mustaches--1920-1930

    Thiol-disuplhide redox equilibria of glutahione metaboloma compounds investigated by tandem mass spectrometry

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    The thiol group of cysteine plays a pivotal role in structural and functional biology. We use mass spectrometry to study glutathione-related homo- and heterodimeric disulfides, aiming at understanding the factors affecting the redox potentials of different disulfide/thiol pairs. Several electrospray ionization (ESI)-protonated disulfides of cysteamine, cysteine, penicillamine, N-acetylcysteine, N-acetylpenicillamine, γGluCySH, HSCyGly, and glutathione were analyzed on a triple quadrupole instrument to measure their energy-resolved tandem mass spectra. Fission of the disulfide bond yields RSH*H+ and RS+ ions. The logarithm of the intensity ratio of the RS+/RSH*H+ fragments in homodimeric disulfides is proportional to the normal reduction potential of their RSSR/RSH pairs determined by nuclear magnetic resonance (NMR) in solution, the more reducing ones yielding the higher ratios. Also in some R1S-SR2 disulfides, the ratio of the intensities of the RSHRHR and RSR ions of each participating thiol shows a linear relationship with the Nernst equation potential difference of the corresponding redox pairs. This behavior allows us to measure the redox potentials of some disulfide/thiol pairs by using different thiol-reducing probes of known oxidoreductive potential as reference. To assist understanding of the fission mechanism of the disulfide bond, the fragments tentatively identified as 'sulfenium' were themselves fragmented; accurate mass measurement of the resulting second-generation fragments demonstrated a loss of thioformaldehyde, thus supporting the assigned structure of this elusive intermediate of the oxidative stress pathway. Understanding this fragmentation process allows us to employ this technique with larger molecules to measure by mass spectrometry the micro-redox properties of different disulfide bonds in peptides with catalytic and signaling biological activity. Copyrigh

    Narrative art and act in the fourth gospel: aspects of the Johannine point of view

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    This thesis assumes that the narrative form of the Fourth Gospel is important for understanding the Gospel's meaning. Narrative is a communicative transaction whereby meaning is transmitted from author to reader via the way the story is told. Meaning is also established by overt speech-acts, and the 'act' performed in the overall structuring of the story. It arises within a context of rule-governed speech behaviour which determines parameters and implications that inform understanding. The Gospel's narrative form meets with readers' conventional expectations about how it relates to ostensive historical reality. Factors internal and external help determine genre. Part one examines aspects of the Gospel's narrative art. The way in which the narrative situation varies over the course of the narrative is outlined. The implied author manipulates the narration to create a close association in the reader’s mind between the narrator and the beloved disciple. In John 3 the voice of the narrator merges with those of Jesus and John. These strategies have implications for the Gospel's theological meaning and the relationship of the implied author to the story world. Speech-act theory elucidates the narrative act by which the implied author conveys the Gospel's message and seeks to induce belief in the reader. Part two considers the Gospel's relationship to historical reference. Factors which influence a decision as to whether or not the Gospel is to be taken as fictional are examined, for example, whether aspects of the narration suggest fictional discourse and whether the speech-acts operate within a 'pretended' world. Descriptive categories for the Gospel as natural narrative and 'display text' are proposed, as is a flexible model of genre, which modulates the poles of 'fiction' and 'history'. An analysis of the Temple Cleansing pericope provides illustration of the Gospel’s status as an historically-based, theological display text
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