634 research outputs found
Colin Dayan: "The Story of 'Cruel and Unusual'"
No full textIncludes descriptive metadata provided by producer in MP4 file: "Thinking Out of the Lunch Box - Video - Colin Dayan: "The Story of 'Cruel and Unusual'."Nashville Public LibraryDepartment of Philosoph
Legal Personhood in the Eyes of Ngaire Naffine, Dean Spade and Colin Dayan
No full textThe concept of legal identity or legal personhood is a subject of contention all over the world and this paper recognises and grapples with that. Moreover, it employs the scholarship of Ngaire Naffine, Dean Spade and Colin Dayan. It succeeds in defining a legal person generally and describes the intricacies of legal personhood; compares and contrasts the work of three scholarsand concludes by assessing the viewpoint and perspective most relevant and suitable to how legal personality is and should be seen universally. <br
"Civilizing" Haiti: Representation, and its Discontents
No full textIncludes descriptive metadata provided by producer in MP4 file: "Thinking Out of the Lunchbox - 'Civilizing' Haiti: Representation, and its Discontents - Thinking Out of the Lunchbox discussion with Colin Dayan, professor of English, Robert Penn Warren Professor in Humanities; Jemima Pierre, visiting fellow, Robert Penn Warren Center for the Humanities; and Jane Landers, associate professor of history." Dayan, Pierre and Landers speak on Apr. 7, 2010, as part of the Thinking Out of the Lunch Box series held at the Nashville Public Library and co-sponsored by Vanderbilt and the public library. Professor of Philosophy David Wood introduces the speakers, who take questions from the audience in a panel discussion after their individual addresses.Nashville Public LibraryPhilosophy Departmen
'The Face as a Battlefield' by Ygal Bursztyn
No full textThis text transposes, in the form of an article, the main themes tackled by the director Ygal Bursztyn in his book Face, Battlefield (Tel Aviv, Hakibbutz Hameuhad, 1990). Daniel Dayan thanks the author and the translator Sonia Hadida for their collaboration on this adaptation, reproduced with the kind permission of the review Hermes.</jats:p
The Law is a White Dog: How Legal Rituals Make and Unmake Persons, by Colin Dayan
No full textThe Law is a White Dog: How Legal Rituals Make and Unmake Persons, by Colin Daya
Clinical, behavioural and pharmacogenomic factors influencing the response to levothyroxine therapy in patients with diagnosed primary hypothyroidism
No full textBackground
Suboptimal thyroid hormone therapy including under-replacement and over-replacement is common amongst patients with hypothyroidism. This is a significant health concern as affected patients are at risk of adverse cardiovascular or metabolic consequences. Despite a growing body of evidence on the effects of various factors on thyroid hormone replacement, a systematic appraisal of the evidence is lacking. This review aims to appraise and quantify the extent to which clinical, behavioural and pharmacogenomic factors affect levothyroxine therapy in patients with primary hypothyroidism.
Methods/Design
The databases Web of Science, Cochrane Library, EMBASE, and PubMed will be searched. Patients must be adults over the age of 18 years, suffering from primary hypothyroidism including overt and subclinical hypothyroidism, and receiving levothyroxine treatment. Studies in children, pregnant women, and patients with secondary or tertiary hypothyroidism will not be included. We will also exclude studies focused on forms of thyroid hormone replacement therapy other than levothyroxine.
The primary outcome is to quantify the effect of clinical, behavioural and pharmacogenomic factors on thyroid stimulating hormone (TSH) levels. Secondary outcomes are the effect these factors have on Thyroxine (T4) and Triiodothyronine (T3) levels, mortality, morbidity, quality of life, treatment complications, adverse effects, physical and social functioning. Studies will be screened through reading the title, abstract, and then full text. Two reviewers will independently extract the data and select articles, and a third reviewer will be consulted if there is any disagreement. We will undertake a meta-analysis of studies in which there is a defined intervention or exposure, patients are receiving levothyroxine for hypothyroidism, there is an appropriate control group of levothyroxine treated patients that are not exposed to the intervention, and the primary outcome is determined by serum TSH levels. Studies will comprise of randomised controlled trials as well as observational data.
Eligible studies will be assessed for bias using the risk of bias tool available in the Cochrane Handbook 2011, and the quality of evidence will be judged according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. A flow diagram describing the data search will be created according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis: The PRISMA Statement. A narrative synthesis will be undertaken in the description of the data, and summary tables will be created of the results.
Discussion
This review will be the first systematic review of this nature. The evidence synthesised will be useful to general practitioners in their management of hypothyroidism. Findings will be disseminated at conferences and in professional and peer-reviewed journals
Corresponding author and mailing address:
No full textThe author is grateful to the organizers and participants of the ‘Reward and decision making in cortico-basal-ganglia networks ’ meeting for much stimulating discussion and feedback, and to Rui Costa, Nathaniel Daw, Peter Dayan, Daphna Joel and Geoffrey Schoenbaum for helpful comments on the manuscript
sj-docx-1-mso-10.1177_20552173221142741 - Supplemental material for Endocrine and multiple sclerosis outcomes in patients with autoimmune thyroid events in the alemtuzumab CARE-MS studies
No full textSupplemental material, sj-docx-1-mso-10.1177_20552173221142741 for Endocrine and multiple sclerosis outcomes in patients with autoimmune thyroid events in the alemtuzumab CARE-MS studies by Colin M. Dayan, Beatriz Lecumberri, Ilaria Muller, Sashiananthan Ganesananthan, Samuel F. Hunter, Krzysztof W. Selmaj, Hans-Peter Hartung, Eva K. Havrdova, Christopher C. LaGanke, Tjalf Ziemssen, Bart Van Wijmeersch, Sven G. Meuth, David H. Margolin, Elizabeth M. Poole, Darren P. Baker and Peter A. Senior in Multiple Sclerosis Journal – Experimental, Translational and Clinical</p
A Martial Meteorology: Carceral Ecology in the US South of Jesmyn Ward’s Sing, Unburied, Sing
No full textDuring a discussion of her novel, Sing, Unburied, Sing, Jesmyn Ward recalls her experience of Hurricane Katrina: “I sat on the porch, barefoot and shaking. The sky turned orange and the wind sounded like fighter jets” (Ward 262). The “weight of history in the South of slavery and Jim Crow makes it hard to bear up,” she continues. The future is full of worry, “about climate change and more devastating storms like Katrina and Harvey” (Block). In her depiction of the wind as fighter jets, Ward imbues the violent elements of the hurricane with a martial quality that demonstrates how weather and, in particular, storms, hold the capacity to unmake the world. Yet it is the history of the US South, of slavery and Jim Crow, that Ward uses to preface her concern about a turbulent future. In doing so, she foregrounds the racial dimensions of the Anthropocene by placing the carceral in conversation with the environment. Sing, Unburied, Sing also explores this much over-looked connection. By examining the novel’s twinning of racial and ecological violence, this essay traces what I call carceral ecology. Crafted from Ward’s imagining of a martial meteorology, carceral ecology transforms climatic phenomena like heat, rain, and storms into tools of western power. The novel thus unearths a southern history in which environmental design and manipulation have been used maintain a carceral state of control. In the end, Ward offers a counternarrative to a white Anthropocene, one that is attuned to the epoch’s entanglement with race
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