1,721,013 research outputs found
Exfoliative cheilitis as a manifestation of factitial cheilitis in a young man
No full textExfoliative cheilitis as a manifestation of factitial cheilitis in a young ma
Idiopathic lichenoid and granulomatous dermatitis
No full textIdiopathic lichenoid and granulomatous dermatiti
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Milia-like calcinosis cutis in Down syndrome: a new case with a review of the literature
Full text linkWe report an 11-year-old girl who presented with white papules on the dorsal and palmar region of the hands bilaterally. The parents reported that the lesions had appeared four months before and some had resolved spontaneously. The girl was suffering from celiac disease, Down syndrome, and alopecia areata treated with topical corticosteroids. At the first visit, the girl presented with alopecia areata, corticosteroid acne, and a dozen white papules located on the hands. On dermoscopy, a whitish structureless area was seen. Histological examination showed the presence of calcium deposits without tissue damage, thus confirming the diagnosis of milia-like idiopathic calcinosis cutis. At 6-month follow up, the lesions had completely disappeared. Milia-like idiopathic calcinosis cutis is a benign cutaneous disorder consisting of calcium deposits in an apparently undamaged dermis and is typically associated with Down syndrome. Up to a quarter of patients have coexisting syringomas. The milia-like papules tend to self-resolve as patients reach adulthood, so a wait-and-see approach is recommended
Coma Blisters in Children: Case Report and Review of the Literature
No full textComa-induced blisters is a rare condition associated with prolonged impairment of conscious level, which is relatively well-known in adults following overdose with barbiturates. However, it has been very rarely described in children. A case of coma-bullae occurring in an 11-year-old child with meningoencephalitis is herein reported. The bullous lesions occurred on the limbs and trunks, and evolved into necrotic ulcers in a few days. No correlation with any drug overdosage was found. A skin biopsy revealed epidermal and eccrine sweat gland necrosis with abundant neutrophils, and thrombosis of the vessels in the lower dermis. A comprehensive review of the literature showed that only 5 cases of coma-bullae in children have been published so far. Coma blistering resolves spontaneously within days or weeks. Diagnosis of coma-bullae may require careful clinical-pathologic correlation to exclude other blistering diseases in children
A case of porokeratosis with predominant follicular involvement
No full textA case of porokeratosis with predominant follicular involvemen
Red eczematous melanoma: a case report with review of the literature
No full textEczematous melanoma is a rare form of amelanotic melanoma appearing clinically as an erythematous macula or plaque, and dermoscopically characterized by the reduction or absence of pigmented network, resulting difficult for an early suspicion and detection. We describe a case of an amelanotic melanoma presented as a reddish, asymptomatic, non-pigmented scaly plaque localized on the left shoulder of a 78-year-old male patient. Histological examination revealed an ulcerated superficial spreading melanoma (Breslow thickness 0.85 mm and Clark level III), associated with epidermal spongiosis and lymphocytic inflammatory infiltrate. A review of the clinical, histological and dermoscopic features of the other 12 published similar cases revealed that eczematous amelanotic superficial spreading melanoma is quite rare, equally distributed in both sexes, more frequent in the elderly, mostly localized at the extremities and usually diagnosed at an advanced stage
Wells’ syndrome in childhood: two case reports with review of the literature
No full textWells’ syndrome, or eosinophilic cellulitis, is a rare disorder manifesting with acute erythematous and edematous plaques which resolve completely. Bullous lesions are uncommon, especially in childhood.We present two pediatric cases of bullous Wells’ syndrome, one 3-year-old boy with atypical cutaneous manifestations and one 6-month-old girl with typical skin lesions. No trigger factors could be identified in both cases. Treatment with topical and systemic steroids was performed. Both patients had no recurrences after two years. Fortyfive pediatric cases of Wells’ syndrome have been reported in the literature with an average age of onset of five years. In only seven cases bullous lesions were present. In about half of the patients a precipitating factor has been identified, including infections, arthropod bites, drug administration and hematologic disorder
Unilateral nevoid telangiectasia syndrome of pregnancy
No full textUnilateral Nevoid Telangiectasia Syndrome (UNTS) is a rare vascular dermatosis characterized by linearly arranged telangiectasias in a unilateral, dermatomal, or blaschkoid pattern that can be congenital or acquired. We report on a 36-year-old
Caucasian female who presented UNTS localized in the supraclavicular dermatomal region. The lesions were present since puberty, but suddenly worsened during pregnancy, and completely resolved after delivery. Histological examination revealed
ectatic blood vessels in the dermis. Immunochemistry showed the expression of estrogen receptors limited to perivascular cells of ectatic vessels but not on endothelial cells. UNTS associated with pregnancy may be due to excessive estrogenic stimulation of pericytes, which in turn allow vasodilatation. This may also explain the spontaneous resolution of the lesions following deliver
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