101,913 research outputs found
Cancer in pregnancy. An association to make one shiver-highlights from 'Cancer in pregnancy. 15 years after', 10-11 October 2019, Milan, Italy
No full textAlthough rare, the treatment of pregnant women with cancer remains a challenging situation that requires strict collaboration between different specialities and experts in different fields. Frequent lack of experience and knowledge about this condition could lead to late diagnosis, imprecise management, suboptimal treatment, and foetal and maternal harm. Until recently, the choice for a woman diagnosed with cancer during pregnancy was either to sacrifice the foetus by administering effective treatment to the mother or to risk potential harm to the mother by withholding chemotherapy. This conference report aims to summarise all different aspects of cancer and pregnancy discussed at this 2-day meeting. Data on the safety (for mother and child) of chemotherapy administered after the first trimester of pregnancy are accumulating together with the recommendation to bring pregnancy as close as possible to its natural duration. Several aspects such as the poor prognosis of breast cancer diagnosed in the year after delivery and the delayed growth of foetuses exposed to chemotherapy despite the quasi-normal duration of pregnancy require further investigation. In this apparently tragic situation, results are excellent and comforting data accumulate so that we can transmit an optimistic feeling to women facing cancer during pregnancy
5-Fluorouracil (FU) with folinic acid (FA) and mitomycin c (MMC) in the adjuvant treatment of colorectal carcinoma. part i. evaluation of toxicity
No full textNinety-six patients with colorectal cancer (stage B2-C) were randomized to the control arm or to receive adjuvant chemotherapy with folinic acid, FU and MMC. Ninety-three patients are evaluable. The median follow up is 12 months. The average time between surgery and the start of therapy is 28 days. Toxicity is evaluable in 36 of 41 treated patients. Four patients (10%) failed to complete the projected treatment due to toxicity. Toxicity observed in 208 courses of therapy was mostly gastrointestinal and hematological. No cases of treatment related death or cancer-associated hemolytic uremic syndrome (C-HUS) were reported. The average relative dose intensity (rDI) of the projected treatment was 82.6%. Our study is ongoing and further patients are required to achieve statistically significant results. © 1991 Humana Press Inc
L’absence dans la jurisprudence après l’unification italienne : le modèle français et ... quelques nouveautés
No full textSi esamina l'applicazione della disciplina dell'istituto dell'assenza nella giurisprudenza italiana postunitaria ponendo in rilievo gli elementi innovativi rispetto alla tradizione francese confluita nel codice Pisanell
In vitro evaluation of drugs active in colorectal carcinoma therapy: A preliminary study in view of the clinical use of chemosensitivity tests
No full textIn vitro evaluation of drugs active in colorectal carcinoma therapy: A preliminary study in view of the clinical use of chemosensitivity test
L’umidità di risalita capillare negli edifici in pietra leccese: fenomeni di degrado fisico-chimico indotti sulle murature e casi applicativi del sistema elettrofisico a neutralizzazione di carica in edifici storici a Lecce
No full textL’interesse per l'idonea conservazione del patrimonio architettonico e per la sua giusta valorizzazione rende crescente l'esigenza di una valutazione attenta delle condizioni microclimatiche interne agli edifici storici, al fine di definire interventi mirati a contenere le pericolose conseguenze dell’attivazione di processi fisici di degrado.
La pietra leccese, ampiamente diffusa nel patrimonio monumentale ed edilizio del Salento, è tra i materiali porosi più facilmente degradabili. In particolare, la pietra ha proprietà e composizione chimico-fisica tali da favorire la risalita capillare di acqua.
Con l’obiettivo di verificare l’efficacia dell’innovativa apparecchiatura “a neutralizzazio-ne di carica” Domodry nel fermare l’umidità di risalita nella pietra e, quindi, favorirne l’asciugamento, sono state avviate prove in laboratorio e sono state effettuate analisi in sito - tuttora in corso - presso tre edifici salentini di elevato valore storico-artistico: la chiesa Cattedrale di Lecce, La Chiesa di San Matteo e l’edificio universitario Buon Pastore, caratterizzati da un degrado documentato dal fenomeno dell’umidita di risalita capillare.
I rilevamenti eseguiti in sito durante il primo anno dall’attivazione dell’impianto di deumidificazione muraria indicano risultati positivi in termini di riduzione dell’iniziale, anomalo contenuto d’acqua della muratura, risultati che comunque saranno compiutamente va-lutati a ciclo sperimentale concluso
Pregnancy and lactation. Risk or protective factors for breast cancer?
No full textPregnancy and lactation represent the most effective protective elements against breast cancer; counter-intuitively breast cancer incidence shows a small but noticeable increase up to 5 years after delivery. The cumulative effect is however favourable and women show a reduction in breast cancer risk which is proportional to the total duration of lactation and to the number of full-term pregnancies
RESEZIONE RETTOCOLICA ANTERIORE CON CONSERVAZIONE E SCHELETRIZZAZIONE DELL'AMI PER CANCRO DEL SIGMA
No full textAn innovative technique for strengthening of masonry edge vaults: experiments and modeling
No full textMasonry edge vaults are typical of southern Italy and in particular of Salento. They are constituted by four barrel webs, whose vertex points do not meet at the crown of the vault as in the cross vault but are moved backwards, leaving in the middle an empty space covered with a double-curvature shell portion. This central shell has the shape of a four-point star, for which reason the structure is also commonly termed “star vault”. This paper summarizes the main results of an experimental investigation on masonry edge vaults strengthened with fiber-reinforced polymer (FRP) composites and subjected to uniform loading with measurement of the lateral thrust. Test results and theoretical predictions are presented and discussed
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