228 research outputs found

    The global food chain

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    Jonathon Porritt is Founder Director of Forum for the Future www.forumforthefuture.org.uk; Chairman of the UK Sustainable Development Commission www.sd-commission.org.uk; and author of Capitalism as if the World Matters (Earthscan, 2007)

    A conceptual review of interprofessional expertise in child safeguarding

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    It is increasingly accepted that practitioners across a range of professional fields must work together in order to promote children's welfare and protect them from harm. However, it has also become apparent that interprofessional working is a challenging area of practice that cannot simply be prescribed through protocols and procedures, nor acquired as a set of technical competences. This article develops the concept of interprofessional expertise in order to explain how practitioners become more proficient at working with others to manage complex child welfare issues. Key principles are outlined with reference to relevant theoretical frameworks, including models of skill acquisition. The article concludes by discussing some potential implications for future research and contemporary developments in child safeguarding practice

    Allylic C—H activation to access anti-1,3-amino alcohol motifs

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    1,3-Amino alcohols are common motifs in a variety of biologically active molecules including antivirals, antibiotics, antifungals, and various alkaloids. Due to their prevalence and utility as synthetic intermediates, a variety of methods have been developed to access these motifs in a diastereoselective fashion, which are outlined in detail herein. This thesis documents a novel approach to access anti-1,3-amino alcohols through an intramolecular palladium (II)/sulfoxide-oxazoline catalyzed C—H functionalization between a terminal olefin and an N-tosyl carbamate, generating anti-1,3-oxazinanones. These motifs can be further elaborated upon, making this method ideal for the late stage diversification of complex molecules and pharmaceuticals. This new method can be carried out in the presence of reactive functionality that is not well tolerated by existing methods.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2020-05-01The student, Jonathon Young, accepted the attached license on 2018-04-25 at 09:29.The student, Jonathon Young, submitted this Thesis for approval on 2018-04-25 at 09:40.This Thesis was approved for publication on 2018-04-25 at 14:08.DSpace SAF Submission Ingestion Package generated from Vireo submission #12470 on 2018-08-31 at 17:30:26Made available in DSpace on 2018-09-04T20:47:30Z (GMT). No. of bitstreams: 2 YOUNG-THESIS-2018.pdf: 17381393 bytes, checksum: e7e97dc99ab1ce290a64d3a5a9836002 (MD5) LICENSE.txt: 4211 bytes, checksum: 6e0b64d3ab5cba30177cd6924932d927 (MD5) Previous issue date: 2018-04-25Embargo set by: Seth Robbins for item 107460 Lift date: 2020-09-04T20:47:38Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 107460 Lift date: 2020-09-04T20:50:11Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 107460 on 2020-09-05T09:15:26Z

    Data and script for Van Berkel et al: Can starlings use a reliable cue of future food deprivation to adaptively modify foraging and fat reserves?

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    Supporting materials for: Can starlings use a reliable cue of future food deprivation to adaptively modify foraging and fat reserves? Menno van Berkela, Melissa Batesona, Daniel Nettlea and Jonathon Dunna* aCentre for Behaviour and Evolution & Institute of Neuroscience, Newcastle University, Newcastle, UK *Author for correspondence (email: [email protected]; telephone: (+44)7730015855; postal address: Institute of Neuroscience, Henry Wellcome Building, The Medical School, Framlington Place, Newcastle University, Newcastle upon Tyne, UK, NE2 4HH). R script and 3 .csv files.</p

    Historical legacies, competition and dispersal control patterns of invasion by a non-native grass, Microstegium vimineum Trin. (A. Camus)

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    Biological invasions can be controlled by a number of factors, and the importance of these factors for individual species can change depending on the spatial scale under consideration. Furthermore, the long-term legacies of past land use may be among the major factors structuring contemporary communities. This study was designed to merge these two lines of thought by observing the processes influencing invasion success of an exotic grass species, Microstegium vimineum. Plots within twenty hardwood forest stands of different ages (40 years old to [greater than] 100 years) were surveyed in central New Jersey for the presence and abundance of this species, and the data was analyzed using simple, multiple linear and logistic regressions, as well as regression trees. At the stand scale, M. vimineum abundance was influenced by age, slope, shrub cover and forest connectivity, with far more predictable responses in younger stands than in old. On the plot scale, forest age and prior use were again the dominant influences on abundance of the invasive. Invasion in old forests was most promoted by thinner canopy cover, while younger stands were most influenced by soil type and distance to forest edge. Further studies along dispersal corridors (streams and trails) in these stands consistently showed more invasion in younger stands than older, but also found the intensity of invasion to be higher along such corridors than through areas without them. Observation of isolated patches confirmed that seed dispersal is mostly short-range without dispersal conduits, with most seeds germinating less than a meter from their parent patch boundaries. Finally, an experimental study of the role of understory shrub cover and litter depth on seed germination and seedling growth showed that shade from shrubs strongly limits survival and growth. Seeds also need to be in contact with mineral soil to establish, but otherwise litter depth does not influence growth. These studies demonstrate that the establishment and spread of this invasive species is affected by complex hierarchies of factors that differ in stands with different land use histories. Land managers can use these differences to design targeted control programs that are more effective and stand-specific.Ph.D.Includes bibliographical references (p. 148-159)

    Case report: Acute appendicitis in appendix duplication

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    Introduction: Duplication of the appendix is a very rare presentation. According to the Cave–Wallbridge classification, there are three types of duplicate appendix. Presentation of case: A 43 year old female presented with classical symptoms of acute appendicitis, with unremarkable inflammatory markers. The diagnosis was confirmed on pre-operative computer tomography (CT). During laparoscopy two tubular structures were identified: one arising from the tenia libera of the caecum adjacent to the terminal ileum and one retrocaecally at the confluence of the teniae. Both structures were excised using a laparoscopic linear stapler. Histopathological analysis demonstrated the accessory structure to be a microscopically unremarkable blind-ended tubular structure. The other specimen demonstrated acute gangrenous inflammation of the appendix. The patient had an uneventful recovery and was discharged home the following day. Discussion: Appendix duplication is rare; however, failure to recognise it in a patient with acute appendicitis could result in a retained source of sepsis, requiring subsequent re-exploration of the abdomen. The case presented here represents a Type B2 according to the Cave-Wallbridge classification and is the most susceptible to inadvertent error due to having appendixes in both typical and atypical anatomical locations. This case also highlights the probability of this diagnosis being missed on pre-operative CT. Conclusion: This case report presents a unique opportunity for surgical trainees to review intra-operative laparoscopic images of a duplicate appendix, both to allow them to recognise this pathology if encountered in the future, and to embed the importance of ruling it out with thorough intra-operative examination

    Case report: Acute appendicitis in appendix duplication

    No full text
    Introduction Duplication of the appendix is a very rare presentation. According to the Cave–Wallbridge classification, there are three types of duplicate appendix. Presentation of case A 43 year old female presented with classical symptoms of acute appendicitis, with unremarkable inflammatory markers. The diagnosis was confirmed on pre-operative computer tomography (CT). During laparoscopy two tubular structures were identified: one arising from the tenia libera of the caecum adjacent to the terminal ileum and one retrocaecally at the confluence of the teniae. Both structures were excised using a laparoscopic linear stapler. Histopathological analysis demonstrated the accessory structure to be a microscopically unremarkable blind-ended tubular structure. The other specimen demonstrated acute gangrenous inflammation of the appendix. The patient had an uneventful recovery and was discharged home the following day. Discussion Appendix duplication is rare; however, failure to recognise it in a patient with acute appendicitis could result in a retained source of sepsis, requiring subsequent re-exploration of the abdomen. The case presented here represents a Type B2 according to the Cave-Wallbridge classification and is the most susceptible to inadvertent error due to having appendixes in both typical and atypical anatomical locations. This case also highlights the probability of this diagnosis being missed on pre-operative CT. Conclusion This case report presents a unique opportunity for surgical trainees to review intra-operative laparoscopic images of a duplicate appendix, both to allow them to recognise this pathology if encountered in the future, and to embed the importance of ruling it out with thorough intra-operative examination
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