39 research outputs found
“Miles Is a Mode; Coltrane Is, Power”: Notes on John Coltrane as Poetic Muse and Michael Harper’s “Alone” in Songlines in Michaeltree (2000)
No full textThis article looks at the ways jazz legend John Coltrane was a muse for many Black Arts era poets and proceeds to discuss how Michael Harper rendered Coltrane in his work, focusing on editorial changes between the 1970 and 2000 versions of Michael Harper’s poem, “Alone”. In it, the author argues that the change marks a revision of the centrality of Coltrane as Harper’s muse from his early to later career
These are the facts; these are the feelings [catalogue essay]
No full text'These are the facts; these are the feelings' is a catalogue essay for the exhibition 'Natural States: three contemporary painters: Clare Woods, Ingo Meller, Daniel Sturgis' at Pier Arts Centre, Orkney. The exhibition ran 18 June-20 August 2016.
The essay considers the three artists' works, the curatorial framework and how the artists' individual works respond to the site specific nature of the Pier Arts Centre, and its collection. It also, upon reflection of the exhibition title, responds to what the 'natural state' of a contemporary exhibition is. The essay considers each artist's process, following interviews undertaken with each of the painters on site in Orkney during the exhibition installation. The text reflects on the three painters' choice of works from the historic collection that their own works are sited next to, which include works by Barbara Hepworth, Margaret Mellis and Ian Hamilton Finlay
Case studies in the digital fabrication of open-source consumer electronic products
No full textThesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2011.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from PDF version of thesis.Includes bibliographical references (p. 67-69).This thesis explores the effects of digital fabrication on the design, production, and customization of consumer electronic devices. It does so through a series of three case studies - a radio, a pair of speakers, and a computer mouse - that combine a custom electronic circuit board with a digitally-fabricated (laser-cut or 3D-printed) enclosure. For each case study, the thesis describes the construction and prototyping of the product and a workshop in which participants modified the design and made the device for themselves. This customization was enabled by the sharing of the design files for the products following the principles and practices of open-source. The case studies are used to draw practical lessons about the application of electronics, the laser-cutter, and the 3D printer in the digital fabrication of consumer electronic products. Implications are drawn for the open-sourcing of each of these elements and for the software tools used to the design them. The case studies also illustrate four modes of production that digital fabrication enables for electronic devices: one-off, artisanal, kit, and a hybrid mass/custom production. Additionally, they shed light on the types of customization and the human roles that digital fabrication implies for consumer electronics. Three main themes emerge: diversity in design and production, personal connection with devices, and leveraging of the power of software for the making of hardware.by David Adley Mellis.S.M
Research participants and research products for 2004–2013 “Students” accounts for each individual reported as an author on a research product, “Advisors” accounts for each faculty member listed as an author.
No full text“Student Research Products” accounts for authorship credit of a research product (institutional paper, oral presentation, poster presentation, and peer-reviewed article). Gender distribution of faculty advisors also shown.</p
In search of common ground: exploring clinical and educational approaches to autism spectrum disorders
No full textIncludes bibliographical references
Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study
No full textObjectives Sublingual microcirculatory monitoring for traumatic haemorrhagic shock (THS) may predict clinical outcomes better than traditional blood pressure and cardiac output, but is not usually performed until the patient reaches the intensive care unit (ICU), missing earlier data of potential importance. This pilot study assessed for the first time the feasibility and safety of sublingual video-microscopy for THS in the emergency department (ED), and whether it yields useable data for analysis.Setting A safety and feasibility assessment was undertaken as part of the prospective observational MICROSHOCK study; sublingual video-microscopy was performed at the UK-led Role 3 medical facility at Camp Bastion, Afghanistan, and in the ED in 3 UK Major Trauma Centres.Participants There were 15 casualties (2 military, 13 civilian) who presented with traumatic haemorrhagic shock with a median injury severity score of 26. The median age was 41; the majority (n=12) were male. The most common injury mechanism was road traffic accident.Primary and secondary outcome measures Safety and feasibility were the primary outcomes, as measured by lack of adverse events or clinical interruptions, and successful acquisition and storage of data. The secondary outcome was the quality of acquired video clips according to validated criteria, in order to determine whether useful data could be obtained in this emergency context.Results Video-microscopy was successfully performed and stored for analysis for all patients, yielding 161 video clips. There were no adverse events or episodes where clinical management was affected or interrupted. There were 104 (64.6%) video clips from 14 patients of sufficient quality for analysis.Conclusions Early sublingual microcirculatory monitoring in the ED for patients with THS is safe and feasible, even in a deployed military setting, and yields videos of satisfactory quality in a high proportion of cases. Further investigations of early microcirculatory behaviour in this context are warranted
Correction: Amendments: Author Correction: ClampFISH detects individual nucleic acid molecules using click chemistry–based amplification
No full textReal-time point of care microcirculatory assessment of shock: design, rationale and application of the point of care microcirculation (POEM) tool
No full textBackground: Despite over a decade of research and technological advances, sublingual microcirculatory monitoring has not yet reached clinical utility. Offline analysis is time consuming and occurs away from the patient. A system to assess the microcirculation at the point of care is desirable. We present a novel 5-point grading system (the point of care microcirculation (POEM) scoring system) that can be used at the point of care during non-invasive sublingual microcirculatory monitoring. Methods: The POEM score is an ordinal scale from 1 (worst) to 5 (best), based on a composite assessment of flow and heterogeneity of four individual sublingual video-microscopy clips. Thirty-two healthcare professionals were trained in how to assign POEM scores. Following training they assigned scores to five test sequences (each consisting of four video clips). They were blinded to clinical status. Inter-user consistency and agreement were assessed using intra-class correlation coefficient (ICC) analysis. In addition, blinded expert scores for 68 video clips were compared to offline computer analysis using traditional microcirculatory parameters including total vessel density (TVD), perfused vessel density (PVD), proportion of perfused vessels (PPV), microcirculatory flow index (MFI) and microcirculatory heterogeneity index (MHI). The time taken to assign each was recorded. Results: Participants showed good inter-rater consistency (ICC 0.83, 95 % CI 0.626, 0.976) and agreement (ICC 0.815, 95 % CI 0.602, 0.974) for assigned POEM scores. Expert scoring of videos correlated with offline values for PVD (R = 0.39; p < 0.05), PPV (R = 0.71; p < 0.001), MFI (R = 0.75; p < 0.001), and MHI (R = 0.68; p < 0.001). POEM scores took less time to assign than conventional offline computer analysis (2 minutes versus 44 minutes). Conclusion: We present for the first time a novel 5-point ordinal scale of microcirculatory flow and heterogeneity that can be used at the point of care. It has minimal inter-user variability amongst healthcare professionals after just 1 hour of training. POEM scores take a short time to assign, and correspond well to traditional offline computer-analyzed parameters
Microcirculatory Impairment Is Associated With Multiple Organ Dysfunction Following Traumatic Hemorrhagic Shock: The MICROSHOCK Study.
No full textOBJECTIVES
To assess the relationship between microcirculatory perfusion and multiple organ dysfunction syndrome in patients following traumatic hemorrhagic shock.
DESIGN
Multicenter prospective longitudinal observational study.
SETTING
Three U.K. major trauma centers.
PATIENTS
Fifty-eight intubated and ventilated patients with traumatic hemorrhagic shock.
INTERVENTIONS
Sublingual incident dark field microscopy was performed within 12 hours of ICU admission (D0) and repeated 24 and 48 hours later. Cardiac output was assessed using oesophageal Doppler. Multiple organ dysfunction syndrome was defined as Serial Organ Failure Assessment score greater than or equal to 6 at day 7 post injury.
MEASUREMENTS AND MAIN RESULTS
Data from 58 patients were analyzed. Patients had a mean age of 43 ± 19 years, Injury Severity Score of 29 ± 14, and initial lactate of 7.3 ± 6.1 mmol/L and received 6 U (interquartile range, 4-11 U) of packed RBCs during initial resuscitation. Compared with patients without multiple organ dysfunction syndrome at day 7, patients with multiple organ dysfunction syndrome had lower D0 perfused vessel density (11.2 ± 1.8 and 8.6 ± 1.8 mm/mm; p < 0.01) and microcirculatory flow index (2.8 [2.6-2.9] and 2.6 [2.2-2.8]; p < 0.01) but similar cardiac index (2.5 [± 0.6] and 2.1 [± 0.7] L/min//m; p = 0.11). Perfused vessel density demonstrated the best discrimination for predicting subsequent multiple organ dysfunction syndrome (area under curve 0.87 [0.76-0.99]) compared with highest recorded lactate (area under curve 0.69 [0.53-0.84]), cardiac index (area under curve 0.66 [0.49-0.83]) and lowest recorded systolic blood pressure (area under curve 0.54 [0.39-0.70]).
CONCLUSIONS
Microcirculatory hypoperfusion immediately following traumatic hemorrhagic shock and resuscitation is associated with increased multiple organ dysfunction syndrome. Microcirculatory variables are better prognostic indicators for the development of multiple organ dysfunction syndrome than more traditional indices. Microcirculatory perfusion is a potential endpoint of resuscitation following traumatic hemorrhagic shock
