86,561 research outputs found

    A phosphorescent copper(i) coordination polymer with sodium 3,5-dimethyl-4-sulfonate pyrazolate

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    A phosphorescent copper(I) coordination polymer with the sodium salt of 3,5-dimethyl-4-sulfonate pyrazole (HLNa) has been prepared and structurally characterized. The presence of the SO3Na substituent in position 4 of the pyrazole ring led to a 3D polymeric species in which an organic/inorganic/organic sandwich motif is observed and repeated along the a axis through zig-zag chains of linear coordinated Cu(I) ions. The inorganic core of the sandwich consists of a trapezoidal grid of Na-ions interconnected by μ-(κO;κ2-O′,O′′)-bridging sulfonates and bridging water molecules; H-bonds can be also found between water molecules and SO3− groups. In the solid state, the copper derivative showed an interesting phosphorescent behavior when irradiated with UV light, with a yellow emission (570 nm) and a good absolute quantum yield (ΦPL = 0.44), together with a remarkable Stokes shift of 2.50 eV

    Renal cysts and diabetes syndrome linked to mutations of the hepatocyte nuclear factor-1β gene: Description of a new family with associated liver involvement

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    Background: Mutations in the hepatocyte nuclear factor (HNF)-1beta gene (TCF2) are responsible for a syndrome characterized by maturity-onset diabetes of the young, a nondiabetic renal disease, genital malformations, and liver dysfunction. Methods: The HNF-1beta gene was screened for mutations in four members of an Italian family with early-onset, nonketotic diabetes or a familiar, nondiabetic renal disease and nonprogressive liver disorder. Results: The genetic analysis revealed an already described nonsense mutation in codon 177 of HNF-1beta gene (R177X) in the four related subjects. Clinical features included diabetes in three of four patients, monolateral renal hypoplasia with cysts in the controlateral kidney in two patients, and bilaterally small hyperechoic kidneys without cysts in the other two patients, Renal function Impairment was severe in one patient, requiring dialysis treatment, and mild in three. Three patients had nonprogressive liver dysfunction, with long-lasting enzyme alterations but no liver insufficiency or jaundice. Conclusion: HNF-1beta gene mutations are associated with a wide variability in severity and pattern of clinical symptoms within the same kindred regarding diabetes and renal impairment. Moderate liver dysfunction may be a so far overlooked component of the syndrome. (C) 2002 by the National Kidney Foundation, Inc

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    New strategies to quantify aluminum hydroxide in powder coatings by thermogravimetric analysis and ATR-FT-MIR spectroscopy coupled with chemometrics

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    Powder coatings industry is a growing trade sector in our days and the process control phase is a critical step with the increasing necessity for rapid methods. In this research, we evaluated the possibility of aluminum hydroxide quantification in powder coatings using thermogravimetric analysis and ATR-FT-MIR spectroscopy. Spiked powder coatings sample standards were realized with a known amount of aluminum hydroxide from 0 to 22% in weight. The thermogravimetric analysis (TGA) was optimized, and the aluminum hydroxide content was determined with a stoichiometric formula based on the delta at the inflection point (DTG curve were derived) in TGA results. The spectroscopic data were acquired, and multivariate regression (Partial Least Squares Regression) was used to model the aluminum hydroxide content with respect to the spectral signal. Models were validated with an external set of real powder coating samples. In this article, a step-by-step model development procedure is illustrated as well as the issues addressed. In addition, models showed the possibility of identifying some additives and resins using only the spectroscopic information

    Factors associated with feed efficiency traits in Italian Jersey cows

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    Feed efficiency in lactating cows is one of the major aspects in modern dairy farm management. Purpose of the present study was to identify sources of variation of body live weight (LW) and feed efficiency traits in a population of 8,516 primiparous Jersey cows. The variables tested included LW, fat corrected milk (FCM), predicted dry matter intake (pDMI), energy corrected milk (ECM), and predicted feed efficiency (pFE_ECM), defined as ECM/pDMI. Linear scoring and age at evaluation were used to estimate LW. Factors associated with such traits were investigated using linear mixed models which included the fixed effects of origin of the paternal grandsire (USA, Denmark, Canada), stage of lactation, year of birth, and age at first calving. Random terms were cow, contemporary group (herd-year-season at linear scoring), and the residual. Mean of LW and pFE_ECM were 435 kg and 1.36, respectively. Feed efficiency was weakly negatively correlated (-0.15) with LW, and pDMI was positive correlated with ECM (0.88). Values of LW ranged from 444.01 to 449.88 kg in cows born between 2006 and 2014. Furthermore, cows with paternal grandsire born in Canada were the heaviest, but they had the lowest values for FCM, pDMI, ECM and pFE_ECM. Feed efficiency, FCM, ECM, and pDMI increased in the first three months of lactation, and then decreased. Kilos of pDMI and FCM increased concurrently with age at first calving and systematically decreased as year of birth proceeds. Energy corrected milk of cows born between 2011 and 2014 was lower than ECM of animals born between 2008 and 2010, consequently resulting in lower pFE_ECM. Late calving Jerseys were less feed efficient compared to early calving contemporaries. Systematic environmental factors associated with feed efficiency will be used to adjust phenotypes for routine genetic evaluation
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