118,015 research outputs found

    Circé : grande valse / exécutée par l'orchestre de San Stefano ; réduite au piano par l'auteur : Gustave Cirilli ; [orn. par] L. Denis

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    Titre uniforme : Cirilli, Gustave (1848-1928). Compositeur. [Circé. Piano]Présentation musicale : Réduction pour pianoValses (piano) -- +* 1800......- 1899......+:19e siècle:Piano, Musique de -- +* 1800......- 1899......+:19e siècle

    Many candidates for a single chair: a critical review of the genetic determinant of flat fruit shape trait in peach (Prunus persica L. Batsch)

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    Known since ancient times, flat-shaped peach (Prunus persica L. Batsch) fruits have aroused considerable research inter- est. Breeding activities for this trait have expanded since the 1980s of the last century in several countries, in parallel with research into its genetic basis. Following the need for molecular markers to assist selection, linkage mapping studies have positioned the flat shape S locus at the end of chromosome 6. Recently, a series of independent studies focused on detailed characterization of the genomic region harbouring the S locus and different hypotheses about the candidate gene or variant were proposed: from a constitutively activated cell death 1 protein (PpCAD1) to a Brassinosteroid insensitive 1-associated receptor kinase 1 group (PpLRR-RLK) until the discovery of large structural variant (a chromosomal inversion of about 1.7 Mb) putatively affecting an OVATE Family Protein (PpOFP1) and a homolog of sucrose non-fermenting 1-related kinase (PpSNF4), respectively, located at the proximal and distal breakpoints. This short review revises historical studies and recent literature, integrating reanalysis of available genetic and genomic data, to provide a critical overview of the topic and highlight avenues for further research

    The Villafranchian perissodactyls of Italy: knowledge of the fossil record and future research perspectives

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    The Villafranchian fossil record of Perissodactyla is of a great interest because the appearance of the genus Equus and disappearance of the genus Tapirus mark important faunal turnovers. Here, we provide new data on Italian Villafranchian Tapiridae, Rhinocerotidae, and Equidae with updates from the last comprehensive review; most relevant are those of the Rhinocerotidae and Equidae. At present only two Villafranchian rhinoceros’ species are documented in Italy: Stephanorhinus jeanvireti and Stephanorhinus etruscus. The two species can be distinguished by several morphological features and by the dimensions of their bones. Stephanorhinus etruscus occurred throughout the Villafranchian; despite the numerous records, its remains are not enough to investigate morphometric trends. The Equidae include seven species including new occurrences of Hipparionine horses and of the genus Equus. The statistical analyses performed on the Equus species show two different evolutionary trends, namely the stenonine lineage “Equus livenzovensis - Equus stenonis” and the small-to-medium-sized lineage “Equus senenzensis - Equus stehlini”, suggesting a different evolution of these species. Moreover, the analyses show close relationships between the Italian Equus stenonis samples and three European Equus stenonis subspecies (E. stenonis vireti, E. stenonis guthi, and E. stenonis pueblensis). We begin to reconsider the validity of E. stenonis subspecies identification in order to provide new perspectives on the taxonomy of this species

    A late occurring “Hipparion” from the middle Villafranchian of Montopoli, Italy (Early Pleistocene; MN16b; ca. 2.5 Ma)

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    We report here for the first time the occurrence in the Montopoli large mammal fossil assemblage of a small equid taxon identified as “Hipparion” sp., associated to the monodactyl large horse Equus cf. livenzovensis. This occurrence has been recognised on a specimen that the late De Giuli (1938-1988) identified as Hipparion sp. in unpublished notes available in the archives of the Vertebrate Palaeontology Laboratory of the Dipartimento di Scienze della Terra at the Università degli Studi di Firenze. Although fragmentary, the specimen documents the occurrence of “Hipparion” at the middle Villafranchian (early Pleistocene, ca. 2.5 Ma) site of Montopoli, one of the latest occurrences of an hipparionine horse in western Europe. The western Eurasian “Hipparion” evolutionary history is summarised herein

    "Inherently Chiral" electrodes: tools for chiral voltammetry and enantiomeric excess evaluation

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    The development of artificial "intelligent" electrodes, capable to discriminate and quantify the enantiomers of chiral analytes, particularly of biological and pharmaceutical interest, is a quite attractive issue in electroanalysis. Obviously, selectivity towards specular molecules can only be achieved on enantiopure chiral electrodes. For this aim, many approaches have been proposed in the last years. However, even the most successful attempts at chiral discimination almost invariably resulted in the detection of a difference in current intensity between the signals of the two antipodes of a chiral probe, without differentiation of their redox potentials; the chiral enantioselective layer is in many instances not of general use, but tailored for a given probe; many preparation procedures are very sophisticated and/or the active films fragile. A winning solution comes from a new class, which we have recently presented1‐3 and patented4, of "inherently chiral" molecular semiconductors, whose stereogenic element is a tailored torsion in the electroactive conductive backbone. The coincidence of the element granting both electroactivity and chirality with the entire molecular backbone results in extraordinary chirality manifestations (such as circularly polarized luminescence), that can be finely and reversibly tuned by the electric potential. Above all, enantiopure electrode surfaces can be easily prepared e.g. by fast electrooligomerization, mostly consisting of cyclic oligomers, highly electroactive and chiral, idealizing conducting polymers without ends and of high complexing ability; they are able to discriminate enantiomers of chiral molecules in terms of large peak potential differences (80‐200 mV and more), with linear dynamic ranges for peak currents, thus affording enantiomeric ratio evaluation. The same spectacular enantioselectivity is obtained on chemically different surfaces of the same structural concept, which demonstrates the general validity of our proposed strategy. A simple reconditioning protocol affords performing more experiments on a single electrode. The new electrodes have been tested with very good results on chiral probes even very different and of applicative interest3 (Dopa and methyl‐Dopa [see our parallel presentation] ofloxacin, norepinephrine, tyrosine, naproxen, catechines, ascorbic acid...), on different supports, including commercial screen printed ones, and in different media (aqueous and nonaqueous ones, as well as small ionic liquid drops on SPEs). This work was supported by Fondazione Cariplo (Grant no. 2011‐0417) References 1. F. Sannicolò, S. Arnaboldi, T. Benincori, V. Bonometti, R. Cirilli, L. Dunsch, W. Kutner, G. Longhi, P.R. Mussini, M. Panigati, M. Pierino, S. Rizzo, Angew. Chem. Int. Ed. 2014, 53, 2623. 2. F. Sannicolò, P.R. Mussini, T. Benincori, R. Cirilli, S. Abbate, S. Arnaboldi, S. Casolo, E. Castiglioni, G. Longhi, R. Martinazzo, M. Panigati, M. Pappini, E. Quartapelle Procopio, S. Rizzo, Chem. Eur. J. 2014, 20, 15296.. 3. S. Arnaboldi, T. Benincori, R. Cirilli, W. Kutner, M. Magni, P.R. Mussini, K. Noworyta, F. Sannicolò, Chemical Science, 2015, 6, 2041. 4. F. Sannicolò, P.R. Mussini, S. Arnaboldi, T. Benincori, R. Cirilli et al., Patent appl. MI2014A000948 (2014

    Isolamento anziani e tecnologie durante il Covid-19

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    La pandemia da Covid-19 ha modificato e sta modificando la nostra vita quotidiana. Tutta la popolazione si è dovuta adeguare alle misure di contenimento del virus proposte dal Governo. Tali misure hanno ridotto la nostra qualità della vita. L’incertezza delle condizioni di salute, la mancanza di interazioni tra familiari e amici, l’isolamento al quale siamo stati costretti, erano e sono necessari per poter limitare la diffusione del virus. In tutto il mondo, compreso in Italia, le persone hanno riprogettato la loro quotidianità grazie all’utilizzo degli strumenti tecnologici. Le tecnologie hanno ridotto la distanza fisica, unendoci socialmente. Come le persone anziane hannostrutturato il rapporto con le tecnologie? E quali tecnologie permettono alle persone anziane di mantenere la loro autonomia? Per rispondere a queste domande è stata effettuata una ricerca sulle applicazioni gratuite presenti online che possono essere utilizzate dagli anziani. All’interno di questo articolo, saranno presentati alcuni strumenti digitali associati a tre macro-aree: un insieme di giochi funzionali all’allenamento cognitivo e strumentale; alcune app dedicate alla salvaguardia della salute; i principali siti per il reperimento di informazioni ufficiali e notizie sicure. I criteri con i quali sono state analizzati gli strumenti digitali sono: facilità nella user experience, accessibilità, amichevolezza dell’interfaccia, valutazioni degli utenti, privacy e sicurezza, interattività. In totale sono stati analizzati 45 strumenti digitali e di questi 10 saranno illustrati in quanto maggiormente vicini ai criteri sopra descritti
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