3,959 research outputs found

    Wandlungen des Mythos

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    Mit seinem Geschichtsromanzyklus "Amazonas", dessen Handlung eine Zeitspanne von rund Vierjahrhunderten umfasst – von den Ereignissen rund um die Eroberung Südamerikas im 16. Jahrhundert bis hin zu der Zeit des pränationalsozialistischen Deutschlands –, führt Alfred Döblin den Leser auf eine Reise durch die verschiedenen Phasen der Entwicklungsgeschichte der menschlichen Zivilisation. Claudia Cippitelli liest Döblins Geschichtsdarstellung als durchgehendes Wandeln des Mythischen und zeigt die Art und Weise, wie diese Evolution des Mythischen auf formaler Ebene realisiert wird. Durch die Untersuchung der textimmanenten Romanpoetik setzt sie sich zum Ziel, die Merkmale und Grundpfeiler der Geschichtsphilosophie festzulegen, die "Amazonas" implizit sind. Dabei steht im Mittelpunkt ihrer Arbeit die Auffassung, dass Döblin durch seine dichterische Darstellung der Weltgeschichte über den Anspruch der Zivilisation reflektiert, eine Wahrheit zu stiften und über die Gewalt, die auf derBasis dieses illusorischen Wahrheits- und Objektivitätsanspruches erzeugt wird

    Tagungsbericht zur internationalen Tagung ‘Conceptions de l’Identité européenne / Konzepte europäischer Identität / Concezioni dell’identità europea II’, Venedig 28. bis 29. März 2022

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    Tagungsbericht zur internationalen Tagung ‘Conceptions de l’Identité européenne / Konzepte europäischer Identität / Concezioni dell’identità europea II’, Venedig 28. bis 29. März 202

    Wandlungen des Mythos. Eine Untersuchung zur impliziten Geschichtsphilosophie der "Amazonas"-Trilogie Alfred Döblins

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    Nella tesi si indaga la filosofia della storia implicita in "Amazonas", trilogia storica di Alfred Döblin che narra prevalentemente gli eventi attorno la conquista europea del Sudamerica. Partendo dalla considerazione che nel romanzo i vari passaggi dell’evoluzione della civiltà vengono rappresentati come fenomeni di violenza, si sostiene la tesi che il romanzo contenga una riflessione di critica della civiltà (Zivilisationskritik) riguardante tutte le epoche e le culture rappresentate. Si propone una lettura secondo la quale nel romanzo la ragione viene ripetutamente svelata come mito, ovvero come narrazione che si convince di riuscire a interpretare la natura e, in questa autoillusione, produce violenza. Tale interpretazione del romanzo viene sostenuta tramite il metodo del close reading effettuato su specifiche parti della trilogia. Il close reading permette di cogliere la corrispondenza che c’è fra contenuto e forma del romanzo: ai cambiamenti di visione del mondo che avvengono nel corso della storia umana – così come delineata nel romanzo – corrispondono variazioni stilistiche, con le quali Döblin riproduce l’evoluzione del narrare (quindi della trasmissione della storia) e svela il desiderio di dominio che si nasconde dietro la narrazione. Mettendo in luce la poetica implicita del romanzo (utilizzo delle fonti e delle tradizioni letterarie, elementi intertestuali, strutturali, linguistici, ecc.) si potrà, inoltre, confutare la diffusa opinione secondo la quale la critica döbliniana alla civiltà sarebbe rivolta esclusivamente al mondo europeo moderno. Nell'analisi si fa riferimento alle teorie di filosofia politica, antropologiche e sociologiche dell'epoca di Döblin che hanno esercitato un'influenza sul suo pensiero o mostrano un'affinità con esso

    Jenseits des Politischen: Alfred Döblins Reflexionen über Deutschland und Europa

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    Jenseits des Politischen: Alfred Döblins Reflexionen über Deutschland und Europ

    Claudia Rankine: An Evening with Claudia Rankine

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    An initiative of the National Endowment for the Arts in partnership with Arts Midwest, the NEA Big Read broadens our understanding of our world, our communities, and ourselves through the joy of sharing a good book. For NEA Big Read: Hampton Roads, that book is Citizen: An American Lyric. NEA Big Read: Hampton Roads, the President\u27s Lecture Series, and the President\u27s Task Force on Inclusive Excellence invite you to a powerful evening with Claudia Rankine, the book\u27s author, hosted by Tim Seibles, Poet Laureate for the Commonwealth of Virginia, and opening with readings by local youth poets. Claudia Rankine has written five collections of poetry, including Citizen: An American Lyric, which was selected for the National Endowment for the Arts\u27 Big Read, and two plays. She also has participated in several video collaborations and edited anthologies including The Racial Imaginary: Writers on Race in the Life of the Mind. Rankine has received fellowships from the MacArthur and Guggenheim foundations. Citizen won several honors, including the National Book Critics Circle Award for Poetry, the PEN Open Book Award and the NAACP Image Award. Citizen also was the only poetry book to be a New York Times nonfiction bestseller. She is the Frederick Iseman Professor of Poetry at Yale University and chancellor of the Academy of American Poets

    Portrait of Claudia Lynn Pittman.

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    Handwritten inscription: Claudia Lynn Pittman, 20 yrs old, Hattiesburg.https://egrove.olemiss.edu/joephoto_c/1129/thumbnail.jp

    Reduced lymphotoxin-beta production by tumour cells is associated with loss of follicular dendritic cell phenotype and diffuse growth in follicular lymphoma

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    Cytokine production is essential for follicular dendritic cell (FDC) maintenance and organization of germinal centres. In follicular lymphoma, FDCs are often disarrayed and may lack antigens indicative of terminal differentiation. We investigated the in situ distribution of cells producing lymphotoxin-beta (LTB), lymphotoxin-alpha (LTA), and tumour necrosis factor-alpha (TNFA) transcripts in human reactive lymph nodes and in follicular lymphomas with follicular or diffuse growth pattern. LTB was the cytokine most abundantly produced in germinal centres. LTB was present in nearly 90% of germinal centre cells whereas LTA and TNFA were detected in 30 and 50%, respectively. Moreover, the amount of LTB expressed in reactive germinal centre cells was 80-fold higher than that of LTA and 20-fold higher than that of TNFA. LTB-positive cells were more numerous in the germinal centre dark zone, whereas expression of the FDC proteins CD21, CD23, VCAM, and CXCL13 was more intense in the light zone. Tumour cells of follicular lymphomas produced less LTB than reactive germinal centre cells. The results of the in situ study were confirmed by RT-PCR; LTB was significantly more abundant in reactive lymph nodes than in follicular lymphoma, with the lowest values detected in predominantly diffuse follicular lymphoma. In neoplastic follicles, low production of LTB by tumour B cells was associated with weaker expression of CD21+/CD23+ by FDCs. Our findings detail for the first time the distribution of LTA-, LTB-, and TNFA-producing cells in human reactive germinal centres and in follicular lymphoma. They suggest the possibility that impaired tumour-cell LTB production may represent a determinant of FDC phenotype loss and for defective follicular organization in follicular lymphoma

    Optimized immunohistochemistry using the D5F3 antibody provides a reliable test for identification of ALK-positive lung adenocarcinomas

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    We used optimized immunohistochemistry (IHC) with the D5F3 antibody for detection of tumours in a prospective study of 307 pulmonary adenocarcinomas. Cases positive by IHC (1+, 2+, 3+) were further investigated by fluorescent in situ hybridization (FISH). Of 307 cases, 22 (7.2%) were moderately intensely positive (2+/3+); 18 of these (82%) were also positive by FISH. Of the four IHC-positive/FISH-negative cases, one was unsuitable for FISH and three had abnormalities of the ALK gene. All cases with weak reactivity with D5F3 (1+) were FISH-negative. The FISH positive/IHC-positive cases with moderately intense reactivity had the typical clinicopathologic features of ALK-positive patients (younger age, p < 0.01; higher frequency in metastatic sites, p < 0.01; cribriform/mucinous/signet histology, p < 0.01; stage IV disease, p < 0.01). In conclusion, our findings indicate that optimized IHC using the D5F3 antibody provides a reliable and inexpensive test for identification of ALK-positive adenocarcinomas. Inclusion of this information in the pathology report at the time of the histological diagnosis might significantly shorten time to treatment

    Homonoia - Concorda - Sammanasya

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    Analysis of the divine figures of Homónoia in the Greek pantheon, Concordia in the Roman pantheon, and Sammanasya in the Vedic pantheon. Claudia Santi is the author of Homónoia; Andrzej Gillmeister is the author of Concordia; Antonio Salvati is the author of Sammanasya. As regards Homónoia, the origin of this personified abstraction seems to be traced back to the political debate of Athens in the last 5th century. Maybe it was created by Antiphon as opposed to stásis, both in the meaning of ‘psychic conflict’ and ‘internal political dissensions, civil war’

    Claudia Emerson, 31st Annual ODU Literary Festival

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    Claudia Emerson was awarded the 2006 Pulitzer Prize in Poetry for her book Late Wife: Poems (LSU Press, 2005). She is also the author of the poetry collections Pharaoh, Pharaoh, and Pinion: An Elegy; all volumes are published in Dave Smith’s Southern Messenger Poets series. Her poems have appeared in Poetry, Southern Review, Shenandoah, TriQuarterly, New England Review and other journals. Emerson is the recipient of a Witter Bynner Fellowship from the Library of Congress and fellowships from the National Endowment for the Arts and the Virginia Commission for the Arts. She is an associate professor of English at the University of Mary Washington in Fredericksburg, Va
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