244 research outputs found
Managing complications in cancer immunotherapy in head and neck cancer
International Journal of Head and Neck Science23107-11
Real time in-vivo miniature endoscopic surveillance system for imaging of nasopharynx.
10.1016/j.wjorl.2020.02.004World J Otorhinolaryngol Head Neck Surg614-
Re-irradiation versus chemo-re-irradiation for unresectable, recurrent/persistent/second-primary head and neck cancer: a pooled-analysis of published data
International Journal of Head and Neck Science4262-7
Self-Assisted Wide-Angle Nasopharyngeal Carcinoma Surveillance Delivery System
10.1115/1.4027070JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME8
Model-free image guidance for intelligent tubular robots with pre-clinical feasibility study: Towards minimally invasive trans-orifice surgery
Comprised of multiple precurved concentric tubes, continuum tubular robots are capable to reach surgical targets while bypassing critical anatomical obstacles during minimally invasive surgeries, such as transnasal and transoral surgeries. To automatically track the surgical target and compensate undesired disturbance, an eye-in-hand image-based visual servoing algorithm is presented in this paper to control in-house continuum tubular robots. The proposed visual servoing approach does not require any prior knowledge on kinametic models of the robots in order to avoid the errors introduced by imaging-sensor calibration and 3D position reconstruction. Preclinical cadaveric experiments have been demonstrated in the paper to illustrate the feasibility of the model-free automatic visual servoing method
The politics of fashion: perceptions of power in female clothing and ornamentation as reflected in the sixteenth-century Chinese novel Jin Ping Mei
This thesis examines issues of female power and influence in sixteenth-century China focusing on how women and their roles were perceived in the changing social environment of the mid-late Ming dynasty. Using aspects of a New Historicist approach, information from contemporary literary and historical sources are analysed alongside each other. With its emphasis on the lives of women and preoccupation with the description of material objects, the late Ming novel Jin Ping Mei forms an important element in the thesis. China in the sixteenth century saw expanding urbanisation, the emergence of a new wealthy merchant class, increasing visibility of women and a questioning of traditional morality. Fashion consciousness, as one of the most conspicuous aspects of the new material culture, is a possible indicator of these trends. Traditional Western theories contend that fashion began in the particular context of Renaissance Europe. However, this study argues that a similar fashion awareness existed in China too, and was manifested in a competitive striving for social status, in this case specifically among women. In contrast to previous studies which downplayed the impact women had on defining traditional Chinese culture, this thesis demonstrates how women and their sartorial choices began to redefine the boundaries of material culture, influencing literati discourse which, in turn, re- influenced female behaviour
Development of a compact continuum tubular robotic system for nasopharyngeal biopsy
Traditional posterior nasopharyngeal biopsy using a flexible nasal endoscope has the risks of abrasion and injury to the nasal mucosa and thus causing trauma to the patient. Recently, a new class of robots known as continuum tubular robots (CTRs) provide a novel solution to the challenge with miniaturized size, curvilinear maneuverability, and capability of avoiding collision within the nasal environment. This paper presents a compact CTR which is 35 cm in total length, 10 cm in diameter, 2.15 kg in weight, and easy to be integrated with a robotic arm to perform more complicated operations. Structural design, end-effector design, and workspace analysis are described in detail. In addition, teleoperation of the CTR using a haptic input device is developed for position control in 3D space. Moreover, by integrating the robot with three electromagnetic tracking sensors, a navigation system together with a shape reconstruction algorithm is developed. Comprehensive experiments are conducted to test the functionality of the proposed prototype; experiment results show that under teleoperation, the system has an accuracy of 2.20 mm in following a linear path, an accuracy of 2.01 mm in following a circular path, and a latency time of 0.1 s. It is also found that the proposed shape reconstruction algorithm has a mean error of around 1 mm along the length of the tubes. Besides, the feasibility and effectiveness of the proposed robotic system being applied to posterior nasopharyngeal biopsy are demonstrated by a cadaver experiment. The proposed robotic system holds promise to enhance clinical operation in transnasal procedures
HIGH THROUGHPUT ANALYSIS OF SINGLE CELLS IN RESPONSE TO MECHANICAL CUES USING DROPLET-BASED MICROFLUIDICS
Ph.DDOCTOR OF PHILOSOPHY (NUSGS
Evidence-Based Endocrine Surgery
10.1007/978-981-10-1124-5Evidence Based Endocrine Surgery201-216Singapor
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