244,958 research outputs found
Factors Influencing Technology Acquisition Decisions of Recipient Pharmaceutical Firms in Taiwan
No full textG protein-coupled receptors: Heterologous regulation of homologous desensitization and its implications
No full textTwo patterns of rapid desensitization have been characterized for G protein-coupled receptors: homologous desensitization, which mainly involves G protein-coupled receptor kinases and arrestins, and heterologous desensitization, which mainly involves protein kinases A (PKA) and C (PKC). In this review, Tsu Tshen Chuang and colleagues discuss evidence to show that PKA and PKC can modify the functional state of the G protein-coupled receptor kinases/arrestin homologous desensitization machinery, providing a novel level of cross-talk in signal transduction. Studies on regulation of G protein-coupled receptor kinases and arrestins confirm that the functional state of this machinery may have important consequences for cellular responsiveness and may represent new targets for therapeutic strategies
Effects of Heat Treatment Microstructures on the Aqueous Stress Corrosion Cracking and Hydrogen Embritelement of a Superplastic 7475 Aluminum Alloy
No full textScall Formation on Ti6Al 4V and Superdux 65 Stainless Steel after Superplastic Forming by Decomposition of (CaCo3+C)
No full textEffects of Filler Metals on the Galvanic Corrosion of Brazed Al2O3-Particulate-Reinforced 6061 Al-Matrix Composite
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The Effect of Heat Treatment on the Corrosion Behavior of a Superplastic 7475 Aluminum Alloy
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