1,739,615 research outputs found
AM Keynote 1: Christopher L. Thompson
No full textChristopher L. Thompson is President and CEO of Brand USA, the nation\u27s public-private partnership dedicated to increasing international visitation to the United States through marketing and promotional efforts. In this role, Chris is responsible for accelerating the organization’s efforts to build and execute effective marketing strategies to increase U.S. travel exports, create jobs, strengthen the economy, and help enhance the image of the United States with people all over the world. Under Chris\u27 leadership, Brand USA has nearly tripled its partnership network and more than doubled its partner contributions and program offerings
Performance of gravel aggregates in superpave mixes with 100/95 angularity
No full textThe current aggregate requirement for aggregate angularity that the NYSDOT requires for their Superpave Hot Mix Asphalt (HMA) is 100/98. With this requirement, many of the gravel quarries in New York State cannot meet that specification. As a result, quarries that are further away from the job site have to transport the aggregates which in turn increases the cost of construction. This paper investigates a multitude of test methods to determine whether the NYSDOT can further lower their Superpave aggregate angularity requirement. Also, this paper delves into "grade bumping".M.S.Includes bibliographical referencesIncludes abstractby Christopher L. Ericso
Henley, Christopher L.
No full textAlso available as a printed booklet and from the Dean of Faculty website https://theuniversityfaculty.cornell.edu/Memorial Statement for Christopher L. Henley, who died in 2015. The memorial statements contained herein were prepared by the Office of the Dean of the University Faculty of Cornell University to honor its faculty for their service to the university
Miller, Christopher L. - Theories of Africans
No full textKrzywicki Janusz. Miller, Christopher L. - Theories of Africans. In: Cahiers d'études africaines, vol. 30, n°120, 1990. pp. 523-526
CPT Christopher L. Colley, 2012 ROTC Faculty
No full textCPT Christopher L. Colley was a member of the military science department ROTC staff at Jacksonville State University in 2012.https://digitalcommons.jsu.edu/rotc_photos/9075/thumbnail.jp
Christopher L. Murphree, 1979 ROTC Commissioning
No full textStudents at Jacksonville State University were commissioned through the ROTC program in ceremonies held April 20, 1979 in Merrill Hall. Shown Mr. and Mrs. E.R. Murphree pin bars on Second Lieutenant Christopher L. Murphree.https://digitalcommons.jsu.edu/rotc_photos/1323/thumbnail.jp
Culture and religion
No full textCulture is the result of, and is itself expressed through, religion, language, institutions and history. Culture is persistent but does change slowly over time. Religion is either one manifestation of culture or itself shapes that culture. This chapter discusses recent contributions to the economics of culture and religion, a literature which was instigated by economic historians and has long been dominated by their work. Its author especially focuses on the role of culture and religion in engendering industrial progress and institutional change
Christopher L. Schilling: The Japanese Talmud: Antisemitism in East Asia
Full text linkBook review of Christopher L. Schilling: The Japanese Talmud: Antisemitism in East Asia. London: Hurst Publishers, 2023, 144 pp
Epigenetic regulation and transcription factor programming enhances neurogenesis in neural stem cells
No full textIn this thesis, we questioned how neuronal and glial phenotypes become specialized. Epigenetic chromatin modifiers and transcription factors were investigated on their roles in programming and maintaining neural lineage restriction. A relatively homogeneous population of cells was generated by deriving immortalizing neural clones from embryonic rat forebrains. Three phenotypes; neuronal, glial and multipotential (GE6, GE2, CTX8), provided contrasting lineages to probe the factors responsible for shaping cell fate. One particular clone, GE6, differentiated into a functional inhibitory like interneuron. Gene expression analysis showed several genes such as Ascl1, Dlx1, Dlx5, may be responsible for the interneuronal phenotype. Epigenetic regulation through histone modifications is believed to be an essential component within the developing nervous system, ultimately affecting cell fate. Testing chromatin signatures on specific neural genes with permissive and repressive histone “marks” shows that chromatin state in undifferentiated precursors correlates with current and predicts downstream gene expression. These results suggest that cell fate may already be predetermined. Furthermore, ChIP sequencing reveals global differences between the representative clones. Extrinsic growth factors, such as BMP2 promotes the neuronal and glial phenotypes in the multipotential cell CTX8. BMP2 asserts its phenotypic response in part by regulating global acetylation enrichment in specific neural gene networks, providing a mechanism to promote and maintain cell fate. Directly altering chromatin marks using a histone deacetylase inhibitor, valproic acid (VPA), globally acetylates the chromatin of CTX8 cells and enhances neurogenesis. VPA treatment was found to also maintain or increase acetylation in specific neuronal genes, such as Ascl1. In addition, several microRNAs thought to play a role in neurogenesis were also epigenetically regulated after VPA treatment. Finally, through the combination of gene expression and epigenetic analyses, direct programming through exogenous expression of Ascl1, Dlx1 and Dlx5 enhanced neurogenesis in CTX8. Gene expression and epigenetic signature mapping provides us with a deeper understanding of how lineage restriction occurs. Learning the programming rules will assist in directing homogeneous populations of neuronal cells to further probe the mechanisms of neurodegenerative diseases.Ph. D.Includes bibliographical referencesby Christopher L. Ricuper
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