4 research outputs found
Effects of storage solutions on in vitro vasoreactivity of radial artery conduits
AbstractObjectives: Surgical preparation of coronary conduits for coronary artery bypass grafting may affect their early and long-term patency; one mechanism may involve endothelial damage. We investigated the effect of 3 commonly used solutions—Ringer's solution, normal saline solution, and heparinized whole blood—on in vitro endothelial and contractile functions of the human radial artery. Methods: Radial artery segments were harvested, cut into 3-mm rings, and stored in unoxygenated Ringer's solution, normal saline solution, or heparinized whole blood for 45 minutes. Rings stored in Krebs solution were used as controls. The rings were then mounted and stretched to an optimal resting tension in oxygenated Krebs solution at 37°C. Contraction responses to potassium, norepinephrine, and serotonin and relaxation responses to acetylcholine, verapamil, and nitroprusside were evaluated. Results: Fifty-six radial artery ring segments from 14 patients (n = 7 rings for each contaction-relaxation curve) were studied. Equilibrated resting tension was 9.6 ± 0.3 mN (5.9 ± 0.2 g), and resting internal circumference was 6.4 ± 0.2 mm. Absolute maximum contraction to potassium was significantly less in rings stored in normal saline solution than in rings stored in control solution (10.7 ± 0.6 g vs 14.5 ± 0.6 g, P < .01; 95% confidence intervals, 0.9-6.9). There was no difference in the contraction to norepinephrine (P = .11) and serotonin (P = .25) among the 3 solutions compared with the control solution. Rings stored in heparinized whole blood had significantly greater endothelium-dependent relaxation to acetylcholine (P < .007), whereas those stored in normal saline solution had reduced responses. Endothelium-independent relaxation to verapamil and nitroprusside were similar among the 3 solutions. Conclusion: Heparinized whole blood is a better physiologic medium for preservation of radial artery endothelial and contractile functions during storage before grafting
Predatoros, or, The brigand's bride : comic opera, in two acts / written by Francis Hart ; composed by Sir W.C.F. Robinson.
Electronic reproduction. Canberra, A.C.T. : National Library of Australia, 2012.; The MS leather bound copy is inscribed by the author: "To George Musgrove from his friend Francis Hart".Predatoros. LibrettoBrigand's bride
Application of inverted J-shaped partial sternotomy in intracardiac operations
Asian Journal of Surgery283218-222AJSU
Candidate Distant Trans-Neptunian Objects Detected by the New Horizons Subaru TNO Survey
Fraser, Wesley C. et al.-- Full list of authors: Fraser, Wesley C.; Porter, Simon B.; Peltier, Lowell; Kavelaars, JJ; Verbiscer, Anne J.; Buie, Marc W.; Stern, S. Alan; Spencer, John R.; Benecchi, Susan D.; Terai, Tsuyoshi; Ito, Takashi; Yoshida, Fumi; Gerdes, David W.; Napier, Kevin J.; Lin, Hsing Wen; Gwyn, Stephen D. J.; Smotherman, Hayden; Fabbro, Sebastien; Singer, Kelsi N.; Alexander, Amanda M.; Arimatsu, Ko; Banks, Maria E.; Bray, Veronica J.; Ramy El-Maarry, Mohamed; Ferrell, Chelsea L.; Fuse, Tetsuharu; Glass, Florian; Holt, Timothy R.; Hong, Peng; Ishimaru, Ryo; Johnson, Perianne E.; Lauer, Tod R.; Leiva, Rodrigo; S. Lykawka, Patryk; Marschall, Raphael; Núñez, Jorge I.; Postman, Marc; Quirico, Eric; Rhoden, Alyssa R.; Simpson, Anna M.; Schenk, Paul; Skrutskie, Michael F.; Steffl, Andrew J.; Throop, HenryWe report the detection of 239 trans-Neptunian objects discovered through the ongoing New Horizons survey for distant minor bodies being performed with the Hyper Suprime-Cam mosaic imager on the Subaru Telescope. These objects were discovered in images acquired with either the r2 or the recently commissioned EB-gri filter using shift and stack routines. Due to the extremely high stellar density of the search region downstream of the spacecraft, new machine learning techniques had to be developed to manage the extremely high false-positive rate of bogus candidates produced from the shift and stack routines. We report discoveries as faint as r2 ∼ 26.5. We highlight an overabundance of objects found at heliocentric distances R ≳ 70 au compared to expectations from modeling of the known outer solar system. If confirmed, these objects betray the presence of a heretofore-unrecognized abundance of distant objects that can help explain a number of other observations that otherwise remain at odds with the known Kuiper Belt, including detections of serendipitous stellar occultations, and recent results from the Student Dust Counter on board the New Horizons spacecraft. © 2024. The Author(s).The authors wish to recognize and acknowledge the very
significant cultural role and reverence that the summit of
Maunakea has always had within the indigenous Hawaiian
community. We are most fortunate to have the opportunity to
conduct observations from this mountain.
This research is based on data collected at the 8.2 m Subaru
Telescope (https://subarutelescope.org/en/) using its prime
focus camera (the Hyper Suprime-Cam), operated by the National
Astronomical Observatory of Japan. The Subaru Telescope
provided the main source of data for this work. We would like
to thank the director, Subaru staff, and the TAC for working with
us to accommodate our complex scheduling requirements.
This research is based on observations from programs GS2019B-FT-102, GN-2020A-DD-103, and GS-2020A-DD-103
obtained at the international Gemini Observatory, a program of
NSFʼs NOIRLab, which is managed by the Association of
Universities for Research in Astronomy (AURA) under a
cooperative agreement with the National Science Foundation
on behalf of the Gemini Observatory partnership: the National
Science Foundation (United States), National Research Council
(Canada), Agencia Nacional de Investigación y Desarrollo
(Chile), Ministerio de Ciencia, Tecnología e Innovación
(Argentina), Ministério da Ciência, Tecnologia, Inovações e
Comunicações (Brazil), and Korea Astronomy and Space
Science Institute (Republic of Korea).
This work was supported by a NASA Keck PI Data Award,
administered by the NASA Exoplanet Science Institute. Data
presented herein were obtained at the Subaru Telescope from
telescope time allocated to the National Aeronautics and Space
Administration through the agency's scientific partnership with
the California Institute of Technology and the University of
California. This research used the Canadian Astronomy Data Centre
facilities operated by the National Research Council of Canada
with the support of the Canadian Space Agency. This work also
made use of the Gemini Observatory Archive, NASAʼs
Astrophysics Data System Bibliographic Services, and the JPL
Horizons web interface (https://ssd.jpl.nasa.gov/horizons.cgi).
New Horizons scientists Stern, Benecchi, Buie, Fraser,
Lauer, Kavelaars, Peltier, Porter, and Verbiscer thank NASA’s
New Horizons Mission (NASW-02008) for funding.
This work made use of the Pan-STARRS1 Surveys (PS1)
and the PS1 public science archive, which have been made
possible through contributions by the Institute for Astronomy,
the University of Hawaii, the Pan-STARRS Project Office, the
Max-Planck Society and its participating institutes, the Max
Planck Institute for Astronomy, Heidelberg and the Max
Planck Institute for Extraterrestrial Physics, Garching, Johns
Hopkins University, Durham University, the University of
Edinburgh, the Queen’s University Belfast, the HarvardSmithsonian Center for Astrophysics, the Las Cumbres
Observatory Global Telescope Network Incorporated, the
National Central University of Taiwan, the Space Telescope
Science Institute, the National Aeronautics and Space Administration under grant No. NNX08AR22G issued through the
Planetary Science Division of the NASA Science Mission
Directorate, the National Science Foundation grant No. AST1238877, the University of Maryland, Eotvos Lorand University (ELTE), the Los Alamos National Laboratory, and the
Gordon and Betty Moore Foundation.
This paper makes use of LSST Science Pipelines software
developed by the Vera C. Rubin Observatory. We thank the
Rubin Observatory for making their code available as free
software at https://pipelines.lsst.io.
We also thank the former and current directors of the Subaru
Telescope, Michitoshi Yoshida and Satoshi Miyazaki, for
opening the Subaru Telescope to collaborate with the New
Horizons mission.
Finally, W.C.F. would like to thank B.C.P. and D.R. for their
insightful comments.
Software: parallel (O. Tange 2011), numpy (C. R. Harris
et al. 2020), matplotlib (J. D. Hunter 2007), TRailed Imaging in
Python, (W. Fraser et al. 2016), astropy (Astropy Collaboration
et al. 2013, 2018), SExtractor (E. Bertin & S. Arnouts 1996).Peer reviewe
