8,961 research outputs found
The Yang-Baxter Equations and Differential Identities
No full textPu, Fu-cho; Sattinger, D.H.. (1989). The Yang-Baxter Equations and Differential Identities. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/4993
The Yang-Baxter Equation for Integrable Systems
No full textPu, Fu-cho; Sattinger, D.H.. (1989). The Yang-Baxter Equation for Integrable Systems. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/4979
Nonlinear analytic and semi-analytic nodal methods for multigroup neutron diffusion calculations
No full textTwo advanced nodal methods for the solution of the multigroup neutron diffusion equations are developed, using the nonlinear coarse-mesh finite difference (CMFD) scheme. Based on the analytic and semi-analytic methods, the relationships between the flux and current on the nodal surface are derived, by which the two-node problem is formulated in an efficient way. The issue of the complex eigenmodes and the instability problem inherent in the analytic solution are considered in order to have an efficient and stable algorithm. The numerical results demonstrate the effectiveness of the two methods
Fu Describing About the Author Himself: A Focus on Ban Gu "You tong fu"
No full textFrom Later Han dynasty onwards, the number of fu describing about the author himself has increased. There are several possible reasons for this, but the most important reason is probably that there was no other genre through which one could express oneself except for fu in this period. For instance, the fiveword poetry was still in the middle way of establishing its own style at that moment. Moreover, in Former Han, there were few opportunities for authors to talk about themselves in detail in fu, because the main readers were emperors and kings of countries. In Later Han, the readers had become more diverse. That is probably the reason why more fu began to mention about the authors themselves in this period. Ban Gu (32-92), who is a representative scholar of Later Han and also a man of letters, expressed his aim by writing "You tong fu". Its main content is that though one's encounter with a disaster or felicity is not always derived from our behavior, we have to have a strong will and take action to overcome disasters. This idea is supported by Ban Gu's experiences of not attaining his aim. Such experiences are common in Chinese authors. One of the earliest examples is Chu Ci. Also, Chu Ci is the one of the origins of fu. It is surprising that authors expressed things about themselves mostly in fu describing journeys. It may be easier to understand this tendency if we think they substituted the heaven wander in Chu Ci with a ground journey. Chu Ci was a model for authors to express their aim which could not come true, even if the journey on the ground and the wander in heaven are different
Regions of High Confidence in Chinese Hamster and CHO-K1 Genome Assemblies
No full textTo assess the quality of the genome assembly, a comparison was done between a publically available AMDS00000000.1 draft assembly of Chinese hamster genome with in-house UMN1.0 to mark consensus regions on the former draft assembly. Using a stringent criterion of contiguous segments larger than 1 Kbp with sequence identity greater than 97 % matching to unique reference and query sequence, 82 % of the total scaffold length consists of consensus regions with the UMN1.0. Since these regions are conserved across two independent assemblies, they are highly likely to have been assembled correctly. Similar analysis was done to compare the CHO-K1 (AFTD00000000.1) and Chinese hamster genome (AMDS00000000.1). Using the above-mentioned criteria 1.72 Gbp (71.9 %) of CHO-K1 genome can be identified as 'high confidence regions'. These regions of consensus were compiled in a bed file containing the scaffold ID, start and end positions of the 'high confidence regions' is available in this data set.Chinese hamster Ovary (CHO) cell lines are the dominant industrial workhorses for therapeutic recombinant protein production. The availability of the genome sequence of Chinese hamster and CHO cells will spur further genome and RNA sequencing of producing cell lines. However, the mammalian genomes assembled using shot-gun sequencing data still contain regions of uncertain quality due to assembly errors. Identifying high confidence regions in the assembled genome will facilitate its use for cell engineering and genome engineering. This dataset includes two genome annotation files that identify the 'high confidence regions' shared by the genome assemblies in comparison. The potential use of these files are to find locations in the publically available genome which are likely to be assembled correctly. These regions can be used confidently for genome engineering.Vishwanathan, Nandita; Bandyopadhyay, Arpan; Fu, Hsu-Yuan; Sharma, Mohit; Johnson, Kathryn; Mudge, Joann; Ramaraj, Thiruvarangan; Onsongo, Getiria; Silverstein, Kevin A. T.; Jacob, Nitya M.; Le, Huong; Karypis, George; Hu, Wei-Shou. (2016). Regions of High Confidence in Chinese Hamster and CHO-K1 Genome Assemblies. Retrieved from the University Digital Conservancy, http://dx.doi.org/10.13020/D6Z304
Online Iterative Adaptive Dynamic Programming Approach for Solving the Zero-Sum Game for Nonlinear Continuous-Time Systems with Partially Unknown Dynamics
No full textThe current study presents an online iterative adaptive dynamic programming approach to resolve the zero-sum game (ZSG) for nonlinear continuous-time (CT) systems containing a partially unknown dynamic. The Hamilton-Jacobian-Issacs (HJI) equation is solved along the state trajectory according to the value function approximation and the policy improvement online. Relaxed dynamic programming is utilized to ensure the algorithm’s convergence. Model and costate networks were established to conduct the method. Computational simulations are performed to present the efficiency of the algorithm.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Control & Simulatio
1‑Formyl-7-hydroxy-6,7-dihydro‑5<i>H</i>‑pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids
No full textPyrrolizidine
alkaloids (PAs) are phytochemicals present in more
than 6000 plant species worldwide; about half of the PAs are hepatotoxic,
genotoxic, and carcinogenic. Because of their wide exposure and carcinogenicity,
the International Programme on Chemical Safety (IPCS) concluded that
PAs are a threat to human health and safety. We recently determined
that PA-induced liver tumor initiation is mediated by a set of four
(±)-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-DNA adducts and proposed that these DHP-DNA adducts
are biomarkers of PA exposure and liver tumor initiation. To validate
the generality of this metabolic activation pathway and DHP-DNA adducts
as biomarkers, it is significant to identify reactive metabolites
associated with this metabolic activation pathway. Segall et al. (Segall et al. (1984) Drug Metab. Dispos. 12, 68−71) previously reported that 1-formyl-7-hydroxy-6,7-dihydro-5H-pyrrolizine (1-CHO-DHP) is generated from the metabolism
of senecionine by mouse liver microsomes. In the present study, we
examined the metabolism of seven hepatocarcinogenic PAs (senecionine,
intermedine, retrorsine, riddelliine, DHR, heliotrine, and senkirkine)
and one noncarcinogenic PA (platyphylline) by human, rat, and mouse
liver microsomes. 1-CHO-DHP was identified as a common metabolite
from the metabolism of these hepatotoxic PAs, but not from platyphylline.
Incubation of 1-CHO-DHP with HepG2 and A549 cells produced the same
set of DHP-DNA adducts, which were identified by both LC/MS MRM mode
and selected ion monitoring analyses through comparison to synthetic
standards. In the incubation medium of 1-CHO-DHP treated HepG2 cells,
both DHP and 7-cysteine-DHP were formed, which were capable of binding
to cellular DNA to produce DHP-DNA adducts. These results suggest
that 1-CHO-DHP is a proximate DNA metabolite of genotoxic and carcinogenic
PAs
Note of congratulations from Jack Huang to Dr. Frank Fu, January 1, 1983
No full textA note of congratulations to Dr. Frank H. Fu (Fu Haojian) from Springfield College Alum, Jack Huang, Class of 1936, dated January 1, 1983. The card has country lane scene on the front, with a tree with pink leaves, a buttfly, and a tree with its leaves still green. There is the roof of a house just visible over the hill. It also says Congratulations. Inside is short message.Mr. Huang wrote a short personal note congratulating him for his efforts and the recent recognition by then President Ronald Reagan, or the actor as he refers to him, and saying how proud the Chinese are of him. An author of 17 textbooks and more than 100 journal articles, Frank H. Fu, G’73, DPE’75, has worked across the world in China, Canada, and the United States. Throughout his career, he has received many distinguished honors, including the Medal of Honor in 2009 by the SAR Government of Hong Kong.
Fu has held positions at institutions such as the Chinese University of Hong Kong and Springfield College, where he served as director of the International Center starting in 1978. Five years later, Fu returned to Hong Kong, but has since remained actively involved with Springfield College, participating in talks on the campus and even hosting a gathering of nearly 60 alumni in Hong Kong.
Currently, Fu is the associate vice president of Hong Kong Baptist University, where he also works as the director of the Dr. Stephen Hui Research Centre of Physical Recreation and Wellness. In addition, Fu is president of the Society of Chinese Scholars on Exercise Physiology and Fitness, chairperson of Hong Kong Coach Education Committee, a research fellow of the Research Consortium of SHAPE America, and an international fellow of the National Academy of Kinesiology
Practical application of on-line partial discharge monitoring technique on 500kV shunt reactor
No full textConsidering the damage mechanism of oil-impregnated paper insulation in power transformers, shunt reactors and other high voltage electrical apparatus caused by partial discharge, a concept of “destructive partial discharge” is introduced in this paper. The intensity of this discharge is regarded as several thousands pico-coulomb (pC) and may cause the insulation a fatal damage. An oil-paper insulation is usually able to withstand this type of partial discharge for a period of time prior to failure. This provides engineers a time window to detect it. This paper describes an on-line partial discharge monitoring system for 500kV shunt reactors. The commission results from 3 single-phase shunt reactors either connected or disconnected to the grid showed that the on-line partial discharge detecting system has a high noise immunising ability. Two years later after the installation, a pre-warning signal was received from one shunt reactor indicating the existence of an intermittent discharge. The acoustic emission system located its position at the low end of the high voltage bushing in the oil. Dissolved gasses analysis (DGA) in the oil suggested the presence of partial discharge, as acetylene (C2H2) was as high as 20ppm. PD activity was further confirmed by a physical examination on the reactor
Lu Yu and Tu Fu
No full textLu Yu 陸游 (1125-1209), the famous patriot poet of the Southern Sung, admired Tu Fu above all the poets of the past, and the deep influence which Tu Fu exercised on him may be seen throughout his work. In spite of this fact, however, there are many differences which mark the lives and works of the two men. As a first step towards a comparative study of the two poets, the author has attempted to discover how Lu Yu evaluated his predecessor, using evidence found in Lu Yu's poems themselves. By Lu Yu's time, Tu Fu was already widely recognized as the greatest Chinese poet. It had become a popular pastime to try to identify individual poems of Tu Fu on the basis of isolated phrases or couplets, or to compose poems made up of clever imitations of various couplets of Tu Fu. But Lu Yu, unlike most of his contemporaries, was less attracted by Tu Fu's poetic technique than by his poetic spirit, and regarded the latter as the most valuable lesson to be learned. He insisted that it was Tu Fu the man rather than Tu Fu the poet, Tu Fu the patriot rather than Tu Fu the artist, who deserved to be most highly admired. This was the foundation upon which Lu Yu's evaluation of Tu Fu rested, and the premise upon which he approached his work
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