162,633 research outputs found
The marriage record of Chitty, J. M. and Bonehillon, Getta
No full textMarriage license for J.M. Chitty and Getta Bonehillon. J.B. Anderson was the officiant
Evaluation of a novel assay for detection of the fetal marker RASSF1A: facilitating improved diagnostic reliability of noninvasive prenatal diagnosis
No full textBackgroundAnalysis of cell free fetal (cff) DNA in maternal plasma is used routinely for non invasive prenatal diagnosis (NIPD) of fetal sex determination, fetal rhesus D status and some single gene disorders. True positive results rely on detection of the fetal target being analysed. No amplification of the target may be interpreted either as a true negative result or a false negative result due to the absence or very low levels of cffDNA. The hypermethylated RASSF1A promoter has been reported as a universal fetal marker to confirm the presence of cffDNA. Using methylation-sensitive restriction enzymes hypomethylated maternal sequences are digested leaving hypermethylated fetal sequences detectable. Complete digestion of maternal sequences is required to eliminate false positive results.MethodscfDNA was extracted from maternal plasma (n = 90) and digested with methylation-sensitive and insensitive restriction enzymes. Analysis of RASSF1A, SRY and DYS14 was performed by real-time PCR.ResultsHypermethylated RASSF1A was amplified for 79 samples (88%) indicating the presence of cffDNA. SRY real time PCR results and fetal sex at delivery were 100% accurate. Eleven samples (12%) had no detectable hypermethylated RASSF1A and 10 of these (91%) had gestational ages less than 7 weeks 2 days. Six of these samples were male at delivery, five had inconclusive results for SRY analysis and one sample had no amplifiable SRY.ConclusionUse of this assay for the detection of hypermethylated RASSF1A as a universal fetal marker has the potential to improve the diagnostic reliability of NIPD for fetal sex determination and single gene disorders
Fibrotic eye muscles, Axenfeld anomaly, flat face, and mild developmental retardation: A new example of the Chitty syndrome.
No full textWe have studied a girl with fibrotic extrinsic eye muscles, Axenfeld anomaly, unusual facial appearance, mild hydrocephaly, and neurodevelopmental delay. Her condition is similar to the one described recently in members of a single family by Chitty et al. [1991, Am J Med Genet 40:417-420]. We suggest that she represents a second example of what may be called the Chitty syndrome
[Report to Chief J. E. Curry, by an unknown author #1]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #2]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
Derwas J. Chitty. The Desert a City. An introduction to the Study of Egyptian and Palestinian Monasticism under the Christian Empire
No full textGuillaumont Antoine. Derwas J. Chitty. The Desert a City. An introduction to the Study of Egyptian and Palestinian Monasticism under the Christian Empire. In: Revue de l'histoire des religions, tome 176, n°2, 1969. pp. 218-220
Barsanuphius and John, Questions and Answers. Critical Edition of the Greek Text with English Translation by Derwas J. Chitty (Patrologia Orientalis, tome XXXI, fascicule 3), 1966
No full textChirat Henri. Barsanuphius and John, Questions and Answers. Critical Edition of the Greek Text with English Translation by Derwas J. Chitty (Patrologia Orientalis, tome XXXI, fascicule 3), 1966. In: Revue des Sciences Religieuses, tome 42, fascicule 1, 1968. pp. 79-81
Barsanuphius and John, Questions and Answers. Critical Edition of the Greek Text with English Translation by Derwas J. Chitty (Patrologia Orientalis, tome XXXI, fascicule 3), 1966
No full textChirat Henri. Barsanuphius and John, Questions and Answers. Critical Edition of the Greek Text with English Translation by Derwas J. Chitty (Patrologia Orientalis, tome XXXI, fascicule 3), 1966. In: Revue des Sciences Religieuses, tome 42, fascicule 1, 1968. pp. 79-81
Things seen in China / by J. R. Chitty; with fifty illustrations.
No full textMode of access: Internet
Murder on the mountain: author talk with Peter J. Wosh
No full textAuthor talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.
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