121,954 research outputs found
Basi biologiche e genetiche dell'attività psichica
No full textBasi Biologiche e Genetiche dell’Attività Psichic
Gli strumenti per il coordinamento della ricerca scientifica: l’accordo di programma introdotto dalla legge n. 168 del 1989
No full textLa diagnosi genetica nelle pratiche di fecondazione assistita
No full textLa legge n. 40 del 2004, pur avendo colmato un ingiustificato vuoto normativo nello svolgimento delle pratiche di fecondazione assistita, sembra tuttavia ridurre oltre misura le opportunità pure offerte da questa pratica medica per soddisfare il desiderio di maternità cosciente e responsabile.
Accanto ad un precoce riconoscimento della soggettività giuridica a favore del concepito, in deroga a quanto altrove disposto (in particolare dall’art. 1 del cod. civ.), il divieto di procedere ad una selezione genetica preimpianto rappresenta un insuperabile ostacolo all’impiego di tecniche di fecondazione per le coppie portatrici di malattie genetiche (es. talassemia), ancorché sterili ovvero infertili.
Coerentemente a quanto già consentito in altri ordinamenti giuridici, sarebbe perciò auspicabile un intervento del nostro legislatore ordinario che, attraverso opportuni aggiustamenti normativi, ponga rimedio alle incoerenze esterne ed interne presenti nella legge n. 40, causa principale di un atteggiamento di rifiuto del precetto proibizionista, come testimoniato dal sempre più diffuso “turismo procreatico” verso i Paesi dotati di una disciplina normativa più permissiva
La partecipazione del cittadino al procedimento di formazione della decisione amministrativa. Brevi note in margine alla legge n. 241 del 1990
No full textEvaluation of the adhesion of fiber posts cemented using different adhesive approaches
No full textThe aim of this study was to investigate the adhesion of fiber posts cemented with luting agents that utilize three currently available adhesive approaches: etch-and-rinse, self-etch, and self-adhesive. Forty-two intact single-rooted human premolars were used in the study. Teeth were divided into six groups. In each group, a different resin cement with its adhesive system (if needed) and a fiber post were used. The groups were classified, according to the adhesive approach, into the following three categories. (i) Etch-and-rinse groups: Calibra resin cement/XPBond adhesive + self-curing activator (SCA)/RadiX Fiber Post (Dentsply Caulk), FluoroCore 2 core build-up material/XPBond + SCA/RadiX Fiber Post (Dentsply Caulk), and MultiCore Flow luting and core build-up material/Excite DSC adhesive/FRC Postec Plus fiber post (Ivoclar Vivadent). (ii) Self-etch group: Panavia F 2.0/ED primer (Kuraray)/RadiX Fiber Post (Dentsply Caulk). (iii) Self-adhesive groups: experimental self-adhesive cement/RadiX Fiber Post (Dentsply Caulk), and RelyX Unicem/RelyX Fiber Post (3M ESPE). The adhesion between the post and the root canal walls was assessed using the 'thin-slice' push-out test. In the test arrangement used, the self-etching approach may offer less favourable adhesion to root canal dentin in comparison with etch-and-rinse and self-adhesive approache
D-aspartate modulates transcriptional activity in Harderian gland of frog, Rana esculenta: Morphological and molecular evidence
No full textIn the green frog, Rana esculenta, a substantial amount Of D-aspartate (D-Asp) is found enclogenously within the Harderian gland (HG) following its synthesis from (L)-aspartate ((L)-Asp) by an aspartate racemase. The frog HG is an orbital seromucoid gland that displays seasonal changes in secretory activity. Our in vivo experiments, consisting of i.p. injection of 2.0 mu mol/g.b.w. (D)-Asp in frogs collected during two periods of differing glandular activity (high or medium-low secretory activity), revealed that HG can to take up and accumulate D-Asp and that this amino acid may modulate the exocrine secretion through a kinase pathway. Atatirnewhenthe gland shows relatively low secretory activity, i.p. administration of (D)-Asp rapidly induced activation of ERK1 and an increase in cells active in RNA synthesis. This increase in transcriptional activity was followed by a significant increase in Mucous secretion. By contrast, administration of exogenous (D)-Asp when HG was showing high activity rapidly induced inhibition of both ERK1 and transcriptional activity. Since D-Asp is known to be recognized by receptors for N-methyl-(D)-aspartic acid (NMDA), it is possible that in the HG, D-Asp mediated NMDA activation may enhance the kinase pathway. The above activation of opposing stimulatory and inhibitory processes could reflect different levels of NMDA-receptor activity, which could vary as a function of the level of gland activity. This study provides the first evidence of a role for this excitatory amino acid in exocrine secretion. The effects of (D)-Asp in HG appear to be specific since they were not seen in frogs treated with other (D)- or (L)-amino acids with known excitatory effects on neurosecretion. (c) 2005 Wiley-Liss, Inc
L'incidenza dei disturbi alimentari in un gruppo di adolescenti Campani: una ricerca empirica
No full textCement thickness at implant-supported single-tooth Lava assemblies: a scanning electron microscopic investigation.
No full textOBJECTIVES:
The fit of implant-supported single-tooth Lava zirconia assemblies was investigated in this study. The implant-abutment interface, the interface between the metallic and the zirconia portion of the abutment and the interface between Lava abutments and copings were evaluated. The adaptation of titanium abutments to implants and Lava copings was investigated as a control.
MATERIAL AND METHODS:
Twenty implants were randomly assigned and connected to Lava abutments (group 1) or titanium abutments (group 2). All specimens were subjected to scanning electron microscopy (SEM) analysis of the fixture/abutment fit. Afterwards, specimens were luted to Lava copings and subjected to a SEM evaluation of the marginal external adaptation of the abutments with the copings. Finally, the samples were embedded in resin, sectioned and subjected to SEM analysis of the following interfaces; group 1: titanium/zirconia interface (between the constitutive components of the Lava abutment) and the zirconia/zirconia interface (between the Lava abutment and the coping); group 2: the titanium/zirconia interface (between the titanium abutment and the Lava coping). Non-parametric analysis of variance and a post hoc test were used for statistical analysis.
RESULTS:
Significant differences emerged in the cement thickness between titanium and zirconia components of the Lava abutments as compared with the thickness measured at the interface between Lava copings and the abutments investigated. No differences were found in cement thickness between Lava copings and the two different abutments.
CONCLUSIONS:
When Lava abutments are used, the most critical cement thickness is the internal interface between its titanium and zirconia components. Lava coping adaptation for both Lava and titanium abutments is within the clinical acceptable range
The effect of pre-sealing tooth preparations with dentin adhesives on permanent crown cementation: a pilot study.
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