1,721,084 research outputs found
W.A. Muller - Biologia dello sviluppo - Zanichelli, Bologna 1999, pp.368, 123 illustrazioni Edizione italiana di W.A. Muller - Developmental Biology - Springer-Verlag, 1997
No full textIntroduzione alla biologia dello sviluppo dei principali organismi modell
Early development of the pituitary gland in Acipenser naccarii (Chondrostei, Acipenseriformes): An immunocytochemical study
No full textEarly development of the pituitary gland in Acipenser naccarii (Chondrostei, Acipenseriformes): an immunocytochemical study
Abstract: The distribution and appearance of secretory cells in the pituitary gland were investigated for the first time in a chondrostean species, Acipenser naccarii, from embryos to juveniles, by immunohistochemistry with mammalian and teleost hormone antisera. On 5.5 day post-fertilization (2.5 days pre-hatching) the pituitary of embryos appears as an oval mass with a narrow central cavity (hypophysial cleft), close to the ventral border of diencephalon under the third ventricle. At this time, no neurohypophysis is observed, the adenohypophysis is not yet structurally divided into pars intermedia (PI) and pars distalis (PD) and only immunoreactive growth hormone cells are detectable. Seven days post-fertilization (1 day pre-hatching) the immunoreactive tireotropic cells appear in the ventral region and the immunoreactive adrenocorticotropic cells in the posterior dorsal one. At hatching, some immunoreactive melanotropic (ir-MSH) cells are visible in the posterior dorsal region and some immunoreactive prolactin cells in the anterior one. Eight days later the immunoreactive somatolactin cells appear along the posterior dorsal border and the immunoreactive gonadotropic I (ir-GtH I) cells in the ventral region. Here, a few ir-GtH II cells finally appear in 76-86 day old juveniles. The gland elongates after hatching and in 8-day old larvae two adenohypophysis regions are identified: a posterior (the presumptive PI) and an anterior one (the presumptive PD). In 156-166 day old juveniles three regions (rostral and proximal pars distalis and pars intermedia) appear and a high number of ir-MSH cells are visible in the rostral region. The first protrusion of neurohypophysis into adenohypophysis is observed in 76-86 day old juveniles and increases with age, branching into PI. The rostro-caudal distribution of the immunoreactive cells follows the spatial expression of the corresponding hormone gene families observed in zebrafish, suggesting similar differentiating mechanisms in teleosts and chondrostean
Greg Gibson, Spencer V. Muse – A Primer of Genome Science – Sinauer Associates, Inc. Sunderland, Massachusetts 2001 Edizione italiana: G. Gibson, S. V. Muse - Introduzione alla genomica – Zanichelli, Bologna 2004, pp. 328.
No full textTesto di introduzione alla scienza genomica, con descrizione dei metodi sperimentali fondamentali e dei metodi teorici di analisi del genoma, ed inoltre dei metodi statistici necessari per la progettazione sperimentale e l'interpretazione dei dati genomici. Il testo contiene inoltre riferimenti ai siti Internet ed alle più importanti banche dati in genomica e proteomica
Histological and Ultrastructural investigation of early gonad development and sex differentiatio in Adriatic sturgeon (Acipenser naccarii, Acipenseriformes, Chondrostei)
No full textGonad development and sex differentiation
from embryos to 594-day-old individuals were investigated
in farmed Acipenser naccarii using light and
transmission electron microscopy. The migrating primordial
germ cells first appear along the dorsal wall of the
body cavity in embryos 1.5 days before hatching. The gonadal
ridge, containing a few primary primordial germ
cells (PGC-1) surrounded by enveloping cells, appears in
16-day-old larvae. At 60 days, the undifferentiated
gonad is lamellar and PGC-1 multiply, producing PGC-2.
In 105-day-old juveniles, a distinct germinal area with
advanced PGC-2 appears on the lateral side near the
mesogonium and the first blood vessels are visible. At
180 days, putative ovaries with a notched gonadal epithelium
and putative testes with a smooth one appear,
together with adipose tissue on the distal side. In 210-
day-old juveniles, active proliferation of germ cells
begins in the putative ovaries, whereas putative testes
still contain only a few germ cells. The onset of meiosis
and reorganization of stromal tissue occurs in ovaries of
292-day-old individuals. Ovaries with developed lamellae
enclosing early oocyte clusters and follicles with perinucleolar
oocytes occur at 594 days. Meiotic stages are
never found, even in anastomozing tubular testes of 594-
day-old individuals. Steroid producing cells are detected
in the undifferentiated gonad and in the differentiated
ones of both sexes. Anatomical differentiation of the
gonad precedes cytological differentiation and female differentiation largely precedes that of the male. Gonad development and differentiation are also associated with
structural changes of connective tissue, viz. collagen-rich
areas are massive in developing testes and reduced
in ovaries
R.G. Kessel - Istologia generale e dei sistemi - Zanichelli, Bologna 2000, pp.624, 585 ill., 64 tavole Edizione italiana di R.G. Kessel - Basic Medical Histology: The Biology of Cells, Tissues and Organs - Oxford University Press, 1998
No full textManuale di istologia di base, corredato da dettagliate descrizioni di tessuti, organi e sistemi, ed arricchito da disegni, modelli ed ampia iconografia fotografica (ottico, SEM e TEM
Voet D., Voet J.G., Pratt C.W. - Fondamenti di biochimica - Zanichelli, Bologna 2007, pp. 1152 Edizione italiana di Donald Voet, Judith G. Voet, Charlotte W. Pratt – Fundamentals of Biochemistry: Life at the Molecular Level - 2nd Edition, John Wiley & Sons, Inc., New York 2006
No full textSeconda edizione italiana del testo classico di biochimica, che mantiene il rigore e la chiarezza della prima edizione ma approfondisce le descrizioni di tecniche e metodiche analitiche, dedicando particolare attenzione alle malattie derivate da difetti metabolici. Ampio spazio è dedicato alla bioinformatica, con descrizione delle principali banche dati genomiche e proteomiche. Capitoli completamente nuovi: funzioni delle proteine, meccanismi di trasduzione del segnale, ruolo dell'RNA nella regolaizone dell'espressione genica. Corredato da problemi, esercizi di calcolo, grafici molecolari, riferimenti bioinformatici e profili biografici dei principali studiosi di biochimica
Effects of diet-induced feminization on the pituitary gland of Anguilla anguilla (L.). Immunocytichemical and ultrastructural studies.
No full textG. Gibson, S. V. Muse - Introduzione alla genomica - Zanichelli, Bologna 2004, pp. 328. A Primer of Genome Science - Sinauer Associates, Inc. Sunderland, Massachusetts 2001; Edizione italiana:
No full textIntroduzione alla scienza del genoma, con descrizione dei metodi sperimentali fondamentali e dei metodi bioinformatici di analisi, corredata da informazioni sulle principali banche dati genomiche e proteomiche dei più importanti organismi modello
T.J. Pritchard, K.D. Alloway - Neuroscienze mediche - Zanichelli, Bologna 2002, pp.480, 316 illustrazioni Edizione italiana di T.J. Pritchard, K.D. Alloway - Medical Neuroscience - Fence Creek Publishing, Madison, Connecticut, 1999
No full textOriginale testo di neuroscienze mediche: ogni capitolo si apre con la descrizione di un caso clinico, che costituisce il punto di partenza per la trattazione degli argomenti contenuti nel capitol
Correlation between age and DNA damage detected by FADU in human peripheral blood lymphocytes
No full textFluorometric analysis of DNA unwinding (FADU) is a fast and reliable method for detecting single strand DNA breaks as an index of DNA damage induced by clastogenic agents. A study of damage detected by FADU was conducted on DNA extracted from peripheral blood lymphocytes of 128 healthy nonsmoking regular donors (ranging in age from 19 to 67 years) and from 5 umbilical cord blood samples. DNA damage was measured as percentage of unwound DNA after alkalinization. Statistical analyses, both parametric (Pearson r correlation coefficient, b regression coefficient, ANOVA) and nonparametric (Kruskal-Wallis H test, Spearman r(s) rank correlation coefficient), support a significant correlation between age of donors and amount of DNA damage. The same results are found when adult donors are divided in four age classes and the ANOVA test performed among the mean percentages of unwound DNA of each class. Furthermore, donors of the same age belonging to different blood groups (A, B, AB and O) do not show any difference in DNA damage detected by FADU
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