450 research outputs found
COMUNITÀ VIRTUALI ED EPATITE C. L’ESPERIENZA DELLA MALATTIA NEI SOGGETTI AFFETTI DA HCV.
No full textLa comunità dei soggetti affetti da HCV, che si raccoglie, solidale, attorno ad un luogo virtuale qual è un Forum, è lo spaccato di una società alle prese con uno dei problemi più impellenti: la salute. Attorno a questo nodo, letteralmente vitale, si intrecciano problemi individuali e collettivi, si intersecano componenti mediche e psicologiche, si intrecciano valutazioni economiche e sociologiche. La situazione si è fortemente evoluta nell’ultimo periodo rendendo operativi nuovi farmaci che vari studiosi, anche solo negli ultimi anni, indicavano in fase di sperimentazione. Informazione, reattività soggettiva, a livello biologico e psicologico, finanziamento pubblico delle terapie, oculatezza scientifica nella classificazione delle tipologie patologiche in funzione della priorità d’accesso alle terapie hanno aperto nuovi scenari. Tuttavia i metodi tradizionali sono ancora largamente diffusi ed utilizzati, l'analisi sociolociga qui riportata intende illustrare lo studio dell'attuale situazione dei pazienti colpiti da HCV inserendo riflessioni sulle nuove prospettive.Gathered around a virtual place such as a Forum, people affected by HCV are the cross-section of a society struggling with one of the most pressing human problems: Health. Around this litteral-vital node, individual and collective issues, medical and psychological components, economic and sociaological assessments intertwine. Recently, the situation has greatly evolved: new drugs are now approved and prescribed, while in the last few years they had just been in their testing process. Depending onthe priority access to treatments, the acquired better knowledge, the psychological and biological response of the individual, public financed therapies and the cautious scientific classification of the pathology have opened up to new scenarios.
However, traditional methods are still largely widespread. The following sociological analysis will present the study of the current situation of HCV patients with some outlooks on the near future
Una tecnica da ritrovare: i focus group
No full textnumero monografico di Sociologia e Ricerca Socialespecial issue of Sociology and Social Researc
Tracing a Vitaliano Brunelli story
No full textRad analizira jednu epizodu iz sinteze povijesti Zadra u srednjemu vijeku autora V. Brunellija s početka XV. stoljeća. Da bi dokazao da je u Zadru i prije 1409. godine postojala jaka promletačka struja koja je već tada pokušavala ovaj grad predati Veneciji, autor vrlo vješto - kombinirajući postojeće podatke i falsificirajući bilješke - uspijeva
stvoriti uvjerljivu sliku. Stoga je ovaj rad preko prosopografije pojedinih čimbenika koji se spominju u Brunellijevoj priči postupno razotkrio zakučice kojima se autor poslužio i dokazao lažnost njegove tvrdnje.This article analyzes an early fifteenth-century episode discussed in the synthesis of the medieval history of Zadar by the author Vitalino Brunelli. To prove that a strong pro-Venetian faction had existed in Zadar even before 1409, the goal of which was to hand the town over to Venice, Brunelli created a persuasive picture by skilfully combining extant data and falsifying annotations. This article relies on the prosopographies of some of the individuals mentioned in the Brunelli story to uncover tricks that the author used and to disprove the validity of his thesis
Per un catalogo collettivo dell'Università di Verona
No full textPresentazione del progetto per la formazione del Catalogo collettivo dell'Università di Verona, tramite adozione del programma Aleph per la gestione integrata delle bibliotech
Attività antiperonosporica su pomodoro e vite di biostimolanti a base minerale, vegetale e animale
No full textIn prove condotte in condizioni controllate di serra e laboratorio è stata studiata l’attività contro gli agenti della peronospora del pomodoro e della vite di due prodotti (Kendal e Pom-
PK) proposti come biostimolanti della produzione, ma accreditati anche della proprietà di stimolare le capacità di autodifesa delle piante dai patogeni. Lo studio è stato condotto su peronospora del pomodoro (Phytophthora infestans) e su peronospora della vite (Plasmopara viticola) attraverso inoculazioni artificiali dei patogeni su piante allevate in vaso e trattamenti singoli prima o dopo l’inoculazione per evidenziare l’attività rispettivamente preventiva e
curativa. Le verifiche hanno dimostrato che entrambi i prodotti sono dotati di una evidente attività antiperonosporica preventiva sia su peronospora del pomodoro, sia su peronospora della vite, che è più marcata allorché vengono applicati nei giorni immediatamente precedenti l’inoculazione. Il Kendal ha inoltre dimostrato una chiara attività curativa a uno e due giorni dall’inoculazione. Entrambi i biostimolanti hanno, peraltro, evidenziato nei saggi in vitro
anche un’azione diretta su P. infestans, che è apparsa di tipo fungistatico
HETEROGENEITY AND DIFFERENT RELATIONSHIP WITH BIOCHEMICAL AND INFLAMMATORY BIOMARKERS FOR THE CIRCULATING CD16+ MONOCYTES SUBSETS IN ABDOMINAL AORTIC ANEURYSMS (AAA)
No full textHETEROGENEITY AND DIFFERENT RELATIONSHIP WITH BIOCHEMICAL AND INFLAMMATORY BIOMARKERS FOR THE CIRCULATING CD16+ MONOCYTES SUBSETS IN ABDOMINAL AORTIC ANEURYSMS (AAA)
Chiara Barisione, G. Ghigliotti, S. Garibaldi, C. Brunelli, G. Spinella, B. Pane, D. Palmieri, P. Spallarossa, P. Fabbi, P. Altieri, D. Palombo
Modulation of innate immunity occurs in AAA, which is an evolution of the atherothrombotic plaque. Monocytes display considerable heterogeneity, and three subsets are identified, based on the differential expression of CD14 and CD16 receptor: the classical CD16- monocytes and the activated CD16+ monocytes, further differentiated into CD14++CD16+ and CD14+CD16+ cells. CD143(ACE) is overexpressed during monocyte/macrophage differentiation.
Higher CD16+ cell number and CD143 expression are present during inflammatory diseases, such as Chronic Kidney disease (CKD). Plasma D-dimer is increased in patients with AAA, and might contribute to the circulating pro-inflammatory setting.
Aim of our work was to determine the monocyte subsets frequency in AAA patients, and its relationship with D-dimer levels, renal function and other parameters of inflammation.
Peripheral blood from 76 patients with large (>55 mm) AAA, and 24 healthy controls was analyzed to determine monocytic CD14++CD16+ and CD14+CD16+ frequencies and CD143 expression by flowcytometry.
AAA patients have higher frequency of CD14++CD16+ and similar levels of CD14+CD16+ monocytes when compared to Controls. In AAA patients, raised D-dimer levels(r:0.440), age (r:0.310), reduced eGFR (r: -0.237) predict increases of CD14++CD16+ counts, while increased levels of Cystatin C (r:0.489), of uric acid (r: 0.277), of monocyte CD143 (r:0.241), and reduced white blood cell count (r:-0.300) predicted increases of CD14+CD16+ counts .
In conclusion, in AAA patients:1) we found a selective expansion of CD14++CD16+ monocyte subset, when compared with Controls; 2) we provided evidence for heterogeneity within the CD16+ monocytes, by
attributing specific relationship between circulating subsets and cell-associated biochemical and inflammatory biomarkers
Chiara Reatti, Tra aula e torchio. Libri e scuola a Bologna da Napoleone all’età della Restaurazione (Bologna, CLUEB, 2020)
No full textAccountability for climate change: a research synthesis through the lenses of the integrated thinking approach
No full textPurpose – The increasing responsibility of organisations towards society and the environment has inverted the relationship between accounting and accountability, leading to accountability-based accounting systems. This study aims to explore the debate on accountability for climate change within the integrating thinking (IT) perspective. Ascertaining the most significant trends in the debate around purposes and performance that characterise climate mitigation engagement and their connections, the study would explore if and to what extent organisations are tackling climate actions.
Design/methodology/approach – A narrative review of the extensive academic literature developed from the Kyoto Protocol to date was performed. After selecting a representative sample, papers were analysed with the support of a new analytical framework that involves three dimensions – answerability, enforcement and outcome – and governance schemes that emerge from the involvement of the private and public sector and civil society. With the support of NVivo software, themes arisen were analysed and coded. Key items were labelled, creating specific nodes and synthesised into the proposed framework.
Findings – A “silo approach” largely characterises the debate on accountability for climate change. The most significant reasons behind the shortcomings of extant climate actions may be retrieved firstly in the weakness of the motivations that guide organisations to operate in a climate-friendly way.
Social implications – This study underlines the need for a 360° integrated approach for strategically tackling climate actions.
Originality/value – This study would represent a further step towards an integrated approach for studying organisations behaviours in the “climate war”, embracing the connectivity between purposes and outcomes, capitals and the relationships amongst the various stakeholders
Progettazione e implementazione del nuovo sito web del MUDESC-Museo della Scuola "Paolo e Ornella Ricca" (TIPOLOGIA TM = Pubblicazione e gestione di siti web e altri canali social di comunicazione e divulgazione scientifica)
No full textAcetyl-L-carnitine prevents serotonin-induced behavioural sensitization and dishabituation in Hirudo medicinalis
No full textSeveral studies suggest that acetyl-L-carnitine (ALC) might influence learning processes. Along this line of investigation, we have previously shown that ALC impaired sensitization and dishabituation induced by nociceptive stimulation of the dorsal skin of the leech Hirudo medicinalis, in the behavioral paradigm of the swim induction (SI). In previous works we showed that 5HT was involved in both sensitization and dishabituation of SI acting through the second messenger cAMP.
In this work, we have reported that for given doses and temporal ranges ALC was able to block sensitization and to impair dishabituation mimicked by the injection of 5-HT or 8Br-cAMP, a
membrane permeable analogue of cAMP. Our results show that a single treatment with 2 mM ALC was the most effective concentration to block the onset of sensitization induced by 5-HT injection and its major effects occurred 11 days after ALC treatment. 2 mM ALC also blocked sensitization induced by 8Br-cAMP injection, whereas, ALC did not completely abolish dishabituation induced by 5-HT or 8Br-cAMP injection at the tested concentrations and at every time point
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