3,878 research outputs found
Effects of physical training on functional status in patients with prolonged mechanical ventilation
Investigation of physical therapy utilization in integrated delivery system among patients with long-term mechanical ventilation
Multipotential Mesenchymal Stem Cells from Femoral Bone Marrow near the site of Osteonecrosis
Removal of Methomyl Pesticide by Adsorption using Novel Hypercrosslinked Polymer of Macronet MN-100
Natalia LL - artystka neoawangardowa
The paper shows Natalia Lach-Lachowicz (Natalia LL) as a neo avant-garde artist whose works in a specific maximalistic way are very close to the main currents of avant-garde trends: new mediality (photography), minimalism, conceptualism, performance, bodyart, pop-art, and feminist art. The author of the article concentrates mainly on the mutual influences of conceptualism, consumptionism, and feminism in Natalia LL’s works and pays attention to the emancipatory potential of her works of the seventies and the eighties
A Non-biotin Polymerized Horseradish-peroxidase Method for the Immunohistochemical Diagnosis of Canine Distemper
Energy flux in isotropic turbulence under large variations of external forcing
We investigate the response of energy flux in isotropic turbulence to step-function like perturbation in external forcing at large length scales. From both physical experiments and direct numerical simulations, we measured the evolution of the Eulerian velocity structure functions, such as , , before and after the perturbation in forcing. In both cases, we observed the cascade of the energy excess at large scales cascade through scales to the dissipative range, which can be used to study the dynamics of the cascade, and in particular, to estimate the relevant time scales
Real-Time Multiple Moving Objects Detection and Tracking with Direct LL-Mask Band Scheme
This paper presents a new approach, direct LL-mask band scheme (DLLBS), for the detection and tracking of moving objects using a low resolution image. Moving object detection is an important basic task for intelligent video surveillance systems, because it provides a focus of attention for post-processing. However, the successful detection of moving objects in a real environment is a difficult task, due to noise cause by fake motion, such as the motion of leaves in trees. Many methods have been developed in constrained environment, for the detection and tracking of moving objects. The DLLBS method can effectively reduce this noise, with low computing cost, in both indoor and outdoor environments. For circumstances where occlusions occur, we propose a new approach, characteristic point recognition (CPR). Together with DLLBS and CPR, the problems associated with occlusions are alleviated. The experimental results indicate that the proposed DLLBS method (for 320 x 240 and 640 x 480 image frames) can provide higher precision in the detection and tracking of moving objects, and multiple moving objects where occlusion is a problem, for real-time intelligent video surveillance applications.SC
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Some rhetorical strategies in later nineteenth-century laboring-class poetry
Structural and functional analysis of the pro-domain of human cathelicidin, LL-37
Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as large precursor molecules with a highly conserved pro-domain known as the cathelin-like domain (CLD). CLDs have high degrees of sequence homology to cathelin, a protein isolated from pig leukocytes and belonging to the cystatin family of cysteine protease inhibitors. In this report, we describe for the first time the X-ray crystal structure of the human CLD (hCLD) of the sole human cathelicidin, LL-37. The structure of hCLD, determined at 1.93 Å resolution, shows the cystatin-like fold and is highly similar to the structure of the CLD of the pig cathelicidin, protegrin-3. We assayed the in vitro antibacterial activities of hCLD, LL-37 and the precursor form, pro-cathelicidin (also known as hCAP18), and we found that the unprocessed protein inhibited the growth of Gramnegative bacteria with efficiencies comparable to the mature peptide, LL-37. In addition, the antibacterial activity of LL-37 was not inhibited by hCLD intermolecularly, since exogenously added hCLD had no effect on the bactericidal activity of the mature peptide. hCLD itself lacked antimicrobial function and did not inhibit the cysteine protease, cathepsin L. Our results contrast with previous reports of hCLD activity. A comparative structural analysis between hCLD and the cysteine protease inhibitor stefin A showed why hCLD is unable to function as an inhibitor of cysteine proteases. In this respect, the cystatin scaffold represents an ancestral structural platform from which proteins evolved divergently, with some losing inhibitory functions
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