162,467 research outputs found

    Les séquelles des entorses latérales de la cheville

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    Pathologie chronique de la cheville du sportif et séquelles d'une entorse. La cheville 'douloureuse' : les fibroses périarticulaires, le conflit astragalien antérieur, les corps étrangers, la cheville dite 'du sportif', les lésions ostéochondrales du dôme du talus, le syndrome du carrefour postérieur, le syndrome du sinus du tarse, les pathologies des tendons fibulaires, les séquelles neurologiques. La cheville 'instable'. L'arthrose tibiotarsienn

    Genomic tests to guide prostate cancer management following diagnosis

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    Introduction: Prostate cancer (PCa) is a common cancer in men, but variable clinical behaviors make its management challenging. Risk stratification is a key issue in disease management. Patient-tailored strategies are strongly advocated to reduce unnecessary treatment while maximizing the oncological outcomes of patient who need active treatment in the primary, adjuvant or salvage setting. Recently, tissue-based biomarkers or genomic tests have become available to improve the clinical decision-making. Areas covered: In this review, the authors present recent evidence about these tissue-based biomarkers, discussing the application of each of them in the clinical setting, focusing on the tests aimed to provide a better risk stratification and to guide decision-making after the diagnosis of PCa (i.e. OncotypeDXR, ProlarisR, ProMarkR, Ki-67, DecipherR, PTEN, PORTOS, AR-V7 and DNA repair gene mutations). Expert commentary: Even if the clinicopathologic features are still the most frequently-used predictors of disease progression, these tools can be helpful in decision-making at every stage of the PCa management. Actually, OncotypeDXR, ProlarisR and DecipherR are recommended in the clinical setting by guidelines at different steps of PCa management. Consequently, further studies are indispensable to better tailor the right therapy for the right patient and at the right time

    [Report to Chief J. E. Curry, by an unknown author #1]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    [Report to Chief J. E. Curry, by an unknown author #2]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    Le port d’anneaux de cheville en Champagne et le problème d’une immigration danubienne au IIIe s. avant J.-C

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    Kruta Venceslas. Le port d’anneaux de cheville en Champagne et le problème d’une immigration danubienne au IIIe s. avant J.-C. In: Etudes Celtiques, vol. 22, 1985. pp. 27-51

    Colloque international de médecine du sport - Mulhouse, 21 mars 1980 : L'entorse de la cheville

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    Compte-rendu de colloque contenant 15 articles : Physiopathologie et classification des entorses de cheville. L'entorse de la cheville, son diagnostic radiologique et les problèmes qui en découlent. Diagnostic dans les entorses graves du coup de pied. Le traitement chirurgical des entorses graves de la cheville chez le sportif. Place du traitement chirurgical dans les entorses graves du coup de pied. Traumatismes de la cheville et karaté. Présentation de 176 cas d'entorses du coup de pied relevés au service de médecine du sport UCL de septembre 1978 au 15 mars 1980, et leur traitement. La place des drogues chimiques dans le traitement de l'entorse tibio-trasienne. Le strapping dans l'entorse de la cheville. Electrothérapie et entorses de la cheville. Part de l'acupuncture en médecine du sport. Approche de l'effort anaérobie dans le relais 4 x 100 m. Information thérapeutique : Indocid et traumatologie sportive

    Murder on the mountain: author talk with Peter J. Wosh

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    Author talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.

    Comparison of Pathological and Oncologic Outcomes of Favorable Risk Gleason Score 3 + 4 and Low Risk Gleason Score 6 Prostate Cancer: Considerations for Active Surveillance

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    PURPOSE: Recent NCCN® (National Comprehensive Cancer Network®) Guidelines® show that patients with biopsy Gleason score 3 + 4/Grade Group 2 but otherwise favorable features are active surveillance candidates. However, little is known about the long-term outcomes compared to that in men in the low risk Gleason score 6/Grade Group 1 group. We sought to clarify the risk of adverse features and oncologic outcomes in surgically treated, favorable Grade Group 2 vs 1 cases. MATERIALS AND METHODS: We queried our prospectively maintained radical prostatectomy database for all 8,095 patients with biopsy Grade Group 1 or 2 prostate cancer who otherwise fulfilled the NCCN low risk definition of prostate specific antigen less than 10 ng/ml and cT2a or less, and who underwent radical prostatectomy from 1987 to 2014. Multivariable logistic regression and Kaplan-Meier methods were used to compare pathological and oncologic outcomes. RESULTS: Organ confined disease was present in 93.9% and 82.6% of Grade Group 1 and favorable intermediate risk Grade Group 2 cases while seminal vesicle invasion was noted in 1.7% and 4.7%, and nodal disease was noted in 0.3% and 1.8%, respectively (all p <0.0001). On multivariable logistic regression biopsy proven Grade Group 2 disease was associated with a threefold greater risk of nonorgan confined disease (OR 3.1, 95% CI 1.7-5.7, p <0.001). The incidence of late treatment (more than 90 days from surgery) in Grade Group 1 vs 2 was 3.1% vs 8.5% for hormonal therapy and 6.0% vs 12.2% for radiation (p <0.001). In the Grade Group 1 vs 2 cohorts the 10-year biochemical recurrence-free survival rate was 88.9% vs 81.2% and the 10-year systemic progression-free survival rate was 99% vs 96.5% (each p <0.001). CONCLUSIONS: Men at favorable risk with Grade Group 2 disease who are considering active surveillance should be informed of the risks of harboring adverse pathological features which impact secondary therapies and an increased risk of cancer progression

    Les imageries du pied et de la cheville

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    Description détaillée des protocoles radiographiques, échographiques, tomodensitométriques et magnétiques appliqués quotidiennement aux principales pathologies du pied et de la cheville

    Mr. Melvin J. Collier, RWWL AUC, June 2011

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    This video is a conversation with Mr. Melvin J. Collier. Mr. Collier talks about his book, "From Mississippi to Africa: A Journey of Discovery". Daniel Le, AUC Woodruff Library, is the interviewer
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