1,721,126 research outputs found

    How good are the current guidelines on endometriosis?

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    Endometriosis is an enigmatic disorder that is fraught with management controversies and very often, there exists deep divides in management strategies amongst the generalist, the specialist who favours surgery, the specialist who favour medical treatment, and those who are equipoised. The lack of clarity on the aetiology of the disease most likely fuels the existing debates and enhance subjective management options

    Portrait of Daphne Pollard, Shanghai, China, ca. 1910 [picture] /

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    Title devised by cataloguer based on acquisitions documentation.; Inscriptions: "Ying Cheong, Shanghai"--Printed on card below image; "Portrait Group & Architectural Photography, Ying Cheong, Canton Road Shanghai, views for sale, Extra copies of this picture can be had at any time by sending No."--Printed on verso.; Condition: Yellowing, pinholes on both upper corners.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-vn4276010; Purchased 2007

    The patient with endometriosis

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    Does intra-uterine insemination have a place in modern ART practice?

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    Intra-uterine insemination (IUI) is a cheaper, less intensive treatment modality for achieving a pregnancy in couples with specific indications. The use of IUI seems to have declined after NICE guideline 2013 (CG 156) recommended IVF over IUI in couples with unexplained and mild male factor infertility. This review examines the current evidence and the applicability of IUI as a first-line option of treatment in couples with unexplained and mild male factor subfertility. The outcome of the review supports this argument. It is likely that IUI will re-emerge as an effective treatment option and thereby increase the choice to patients. However, there is a need for ongoing research and investment into funding of good quality trials to improve and strengthen the evidence base.</p

    Acupuncture in the treatment of infertility

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    The potential benefits of acupuncture need further investigation....The benefits of acupuncture and TCM in the treatment of infertile couples can be found in early Chinese medical ... more widely for a range of conditions. Its efficacy in the treatment of infertility remains ... pregnancy rates in women undergoing IVF

    The safety of hormone replacement therapy in gynecological cancer survivors

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    Treatment of gynecological cancers often induces a premature menopause. Plus advancing treatments mean more gynecological cancer survivors are living to physiological menopause. Hormone replacement therapy (HRT) has proven substantial long-term benefits in physiological menopause and premature menopause particularly. We aimed to evaluate the current evidence on the safety of HRT in gynecological cancer survivors to help clinicians counsel these patients. HRT is not contraindicated in most gynecological cancer survivors, as evidence available often shows safety or even benefit with HRT use. However, HRT is contraindicated in a few cancers-in low-grade serous ovarian carcinoma, high-risk endometrial carcinoma, and some uterine sarcomas. Caution is advised in high-grade serous, late-stage endometrioid, and granulosa ovarian carcinomas when there is substandard evidence demonstrating safety, but also a theoretical harm present. Due to deficient large randomized controlled trials and methodological biases being present in most studies, HRT use needs to be individualized in most cancers-ovarian carcinomas, endometrial carcinomas, and cervical adenocarcinomas. Justification for HRT use is strong, and HRT is not contraindicated in most gynecological cancers due to largely reassuring evidence. More robust long-term data are needed for further reliable guidance for clinicians and patients.</p

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