352 research outputs found
DNA templated Click Chemistry via 5-vinyl-2′-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation
501100001659 German Research Foundation501100000925 National Health and Medical Research Council501100000781 European Research Counci
Cooperation in the sphere of regional security strengthening – priority task of SCO
The author insists that cooperation in the sphere of security remains the main task of SCO. The achievements of recent 10 years as well as new threats and challenges for security are considered, the author argues for necessity to provide common for all members of SCO legal basis for further approaches to security issues in the region of Central Asia
Synchronization of coupled neutral-type neural networks with jumping-mode-dependent discrete and unbounded distributed delays
This is the post-print version of the Article. The official published version can be accessed from the links below - Copyright @ 2013 IEEE.In this paper, the synchronization problem is studied for an array of N identical delayed neutral-type neural networks with Markovian jumping parameters. The coupled networks involve both the mode-dependent discrete-time delays and the mode-dependent unbounded distributed time delays. All the network parameters including the coupling matrix are also dependent on the Markovian jumping mode. By introducing novel Lyapunov-Krasovskii functionals and using some analytical techniques, sufficient conditions are derived to guarantee that the coupled networks are asymptotically synchronized in mean square. The derived sufficient conditions are closely related with the discrete-time delays, the distributed time delays, the mode transition probability, and the coupling structure of the networks. The obtained criteria are given in terms of matrix inequalities that can be efficiently solved by employing the semidefinite program method. Numerical simulations are presented to further demonstrate the effectiveness of the proposed approach.This work was supported in part by the Royal Society of the U.K., the National Natural Science Foundation of China under Grants 61074129, 61174136 and 61134009, and the Natural Science Foundation of Jiangsu Province of China under Grants BK2010313 and BK2011598
Enhanced reversibility of the magnetoelastic transition in (Mn,Fe)<sub>2</sub>(P,Si) alloys via minimizing the transition-induced elastic strain energy
Magnetocaloric materials undergoing reversible phase transitions are highly desirable for magnetic refrigeration applications. (Mn,Fe)2(P,Si) alloys exhibit a giant magnetocaloric effect accompanied by a magnetoelastic transition, while the noticeable irreversibility causes drastic degradation of the magnetocaloric properties during consecutive cooling cycles. In the present work, we performed a comprehensive study on the magnetoelastic transition of the (Mn,Fe)2(P,Si) alloys by high-resolution transmission electron microscopy, in situ field- and temperature-dependent neutron powder diffraction as well as density functional theory calculations (DFT). We found a generalized relationship between the thermal hysteresis and the transition-induced elastic strain energy for the (Mn,Fe)2(P,Si) family. The thermal hysteresis was greatly reduced from 11 to 1 K by a mere 4 at.% substitution of Fe by Mo in the Mn1.15Fe0.80P0.45Si0.55 alloy. This reduction is found to be due to a strong reduction in the transition-induced elastic strain energy. The significantly enhanced reversibility of the magnetoelastic transition leads to a remarkable improvement of the reversible magnetocaloric properties, compared to the parent alloy. Based on the DFT calculations and the neutron diffraction experiments, we also elucidated the underlying mechanism of the tunable transition temperature for the (Mn,Fe)2(P,Si) family, which can essentially be attributed to the strong competition between the covalent bonding and the ferromagnetic exchange coupling. The present work provides not only a new strategy to improve the reversibility of a first-order magnetic transition but also essential insight into the electron-spin-lattice coupling in giant magnetocaloric materials.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.RST/Fundamental Aspects of Materials and Energ
On the Translation of English Hard News under Inter-cultural Background
The author firstly introduced the characteristics of hard news form the perspectives of the structure, linguistic features and language style. Secondly, numerous cultural background factors are classified into six types including geographical environment, life style, traditional customs, religious beliefs, historical allusion and literature connotations which are the underlying causes of cultural barriers occurred in the hard news translation. To remove the cultural barriers, based on the Lawrence Venuti’s (1995) foreignization and domesticaiton translation theory, the paper presents principles for hard news translation. By giving a large number of instances of hard news translations, this paper mainly focuses on such issues as the characteristics of hard news, the influence of the inter-culture on the hard news translation, and relevant translation strategies, and last but not least, attaches significance to the inter-culture awareness of the translator during the process of hard news translation.</jats:p
Mid-Infrared Broadband Achromatic Metalens with Wide Field of View
Metasurfaces have the ability to flexibly control the light wavefront, and they are expected to fill the gaps of traditional optics. However, various aberrations pose challenges for the application of metasurfaces in the wide angle and wide spectral ranges. The previous multi-aberration simultaneous optimization works had shortcomings such as large computational load, complex structure, and low generality. Here, we propose a metalens design method that corrects both monochromatic and chromatic aberrations simultaneously. The monochromatic aberration-corrected phase distribution is obtained by the optical design, and the chromatic aberration is reduced by using the original search algorithm combined with dispersion engineering. The designed single-layered wide-angle achromatic metalens has a balanced and efficient focusing effect in the mid-infrared band from 3.7 μm to 5 μm and a wide angle of ±30°. The design method proposed has the advantages of low computational load, wide application range, and easy experimental fabrication, which provides new inspiration for the development of generalized software for the design and optimization of metasurfaces
The Reachability Query over Distributed Uncertain Graphs
Reachability, one of the most fundamental queries over uncertain graphs, which asks the probability that two given query vertices are reachable over an uncertain graph. Although this problem has been widely studied, the existing works are all processed in a single server. However, as graph data becomes larger, it usually cannot be stored in a single server. Moreover, processing probabilistic reachability queries is #P-complete, so the calculation is very expensive even on small graphs. Thus, in this paper, our purpose is to develop efficient distributed strategies to firstly pick out all the maximal subgraphs whose reachability probabilities can be calculated in polynomial time efficiently. After this step, only a small graph remains, and we provide an approximate method. Extensive experimental studies show that our distributed algorithms are efficient and have a low communication cost.</p
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