329,332 research outputs found
Validity of the Novel Taiwan Lymphoscintigraphy Staging and Correlation of Cheng Lymphedema Grading for Unilateral Extremity Lymphedema
No full textOBJECTIVE: The aim was to validate the new Taiwan Lymphoscintigraphy Staging, correlate it with Cheng Lymphedema Grading (CLG) and evaluate the treatment outcomes of unilateral extremity lymphedema. BACKGROUND: No consensus has been reached for diagnosis and staging for patients with lymphedema among medical specialties. METHODS: We included 285 patients with unilateral extremity lymphedema using lymphoscintigraphy. Lymphoscintigraphy was correlated to clinical symptoms and signs, and classified into normal lymphatic drainage, partial obstruction, and total obstruction. Inter- and intraobserver reliability of Taiwan Lymphoscintigraphy Staging, correlation between Taiwan Lymphoscintigraphy Staging and clinical findings were conducted. Patients were categorized in "surgical" (n = 154) or "nonsurgical" (n = 131) groups for outcome evaluation. RESULTS: Lymphoscintigraphy found 11 patients (3.9%) with normal lymphatic drainage, 128 (44.9%) with partial obstruction, and 146 (51.2%) with total obstruction. Taiwan Lymphoscintigraphy Staging showed high interobserver agreement [intraclass correlation coefficient: 0.89 (95% confidence interval, 0.82-0.94)], and significantly correlated to computed tomography volumetric difference (r = 0.66, P < 0.001) and CLG [intraclass correlation coefficient: 0.79 (95% confidence interval 0.72-0.84)]. At a mean follow-up of 31.2 ± 2.9 months, significant improvement in the circumferential difference (from 23.9% ± 17.6% to 14.6% ± 11.1%; P = 0.03) with a mean circumferential reduction rate of 40.4% ± 4.5% was found in surgical group. At a mean follow-up of 26.6 ± 8.7 months, the nonsurgical group had increase of mean circumferential difference from 24.0% ± 17.2% to 25.3% ± 19.0% (P = 0.09), with a mean circumferential reduction rate was -1.9% ± 13.0%. CONCLUSIONS: The Taiwan Lymphoscintigraphy Staging is a reliable diagnostic tool, correlated with clinical findings and CLG, aiding in the selection of the appropriate treatment to achieve favorable long-term outcomes in unilateral extremity lymphedema
Clean to dirty limit and<i>T</i><sub>c</sub>suppression in NdFeAsO<sub>0.7</sub>F<sub>0.3</sub>studied by<i>H</i><sub>c2</sub>analysis
No full textIn this work, we investigate the temperature dependence of the upper critical field, dH c2/dT, in an increasingly disordered NdFeAsO0.7F0.3 (NdFeAs(O,F)) single crystal that has been progressively irradiated up to a 5.25 ×1016 cm- 2 total particle dose. For the H||ab-plane, dH c2/dT does not vary remarkably with irradiation, while for the H||c-axis it increases sharply after the first irradiation of 3.60 ×1015 cm-2 and then more gradually with further irradiation doses. Focusing on the H||c-axis, we develop a phenomenological analysis of the H c2 slope which allows us to inspect the crossover from the clean to the dirty regime. From the H c2 slope normalized to the critical temperature and to its clean limit value, we extract the ratio of the coherence length ξ BCS to the mean free path and we find that when T c is reduced by a factor of four from its pristine value, ξ BCS/ becomes as large as ∼7 and reaches values of ∼1.8 nm, indicating that NdFeAs(O,F) is well into the dirty regime. Our analysis of the H c2 slope also allows us to compare the pair-breaking effectiveness of scattering in different superconductors, showing similarity between unconventional NdFeAs(O,F) and moderate-T c phonon-mediated devices, such as MgB2 and A15 compounds, but much a stronger difference with YBa2Cu3O7-δ. This work thus shows that dH c2/dT is a reliable parameter, providing an alternative to residual resistivity, for investigating the pair-breaking mechanism induced by impurity scattering in superconductors
Physician performance information and consumer choice: a survey of subjects with the freedom to choose between doctors
No full textSerum fatty acid composition in primary school children is associated with serum cholesterol levels and dietary fat intake
No full textISGG: Cooperative Mission in the AI Era
No full textAt the 21st International Conference on Geometry and Graphics (ICGG2024, August, 2024), an international panel was organized with the In- stitutional Members and Associated National Organizations of ISGG to discuss cooperative mission in the AI era and its relation to the International Society for Geometry and Graphics. This is a summary of the discussion with the panel members Luigi Cocchiarella (Italy), Liang-Yee Cheng (Brazil), Michal Zamboj (Czech Republic), Hans-Peter Schro ̈cker (Austria), Hongming Cai (China), Eva Wohlleben (Germany), Stefano Bertocci (Italy), and Hirotaka Suzuki (Japan)
Influence of Acid Adaptation on the Tolerance of Escherichia coli O157:H7 to Some Subsequent Stresses
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Journal for Geometry and Graphics
No full textThe singular coincidence in 2022, 25th anniversary of the publication of the first issue of the Journal of Geometry and Graphics (JGG), 30th anniversary of the establishment of the International Society for Geometry and Graphics (ISGG), and 80th birthday of Hellmuth Stachel, Professor of Geometry at the Technical University of Vienna (now retired), founder and former Editor in Chief of the JGG, and co-founder of ISGG, suggested the idea of this special issue.
The Editorial Board, formed by the current Editor in Chief who launched the proposal, the President, the Vice-Presidents, and the Treasurer of ISGG, decided to publish the issue as part of the JGG series, in order to reach the audience of readers familiar with the journal, and with the person to whom this issue is dedicated.
The volume includes two editorial sections, “Personal Memories” and “Scientific Contri butions”, in the aim of reflecting the wide spectrum of competences and interests of Hellmuth Stachel, deepened and shared in a life actively spent between research and education, without missing some personal items and anecdotes.
“Personal Memories” consist of short contributions written by people being, or having been, closely connected with Hellmuth Stachel over more than three decades, who share their personal records about his role in science, education, and community services.
“Scientific Contributions” refer to the world wide scientific impact of Hellmuth Stachel, and consist of a number of papers on topics related to Geometry and Graphics, written by authors of various backgrounds and generations, invited from the three ISGG world regions (Asia/Australia/Oceania, Europe/Near East/Africa, North America/South America).
May this special issue celebrating such an exemplary academic profile, inspire all the readers, as well as the whole JGG and ISGG communities, and, why not, initiate a new editorial line inside the JGG series.
On behalf of JGG and ISGG, we warmly address to Professor Hellmuth Stachel our birthday wishes, and cordial greetings to his family and his wife Mrs. Henrike.
The Guest Editorial Board of JGG 26/1
Liang-Yee Cheng, Luigi Cocchiarella, Hans-Peter Schr ̈ocker, Kumiko Shiin
The Impacts of Lymph on the Adipogenesis of Adipose-Derived Stem Cells
No full textBackground: The pathophysiology of adipose proliferation or differentiation in extremity lymphedema has not been thoroughly studied. This study investigated the impacts of the lymph harvested from lymphedematous limbs on the adipogenesis of adipose-derived stem cells (ASCs). Methods: ASCs were isolated from the adipose tissue of normal extremities and cultured with lymph collected from Cheng lymphedema grade III to IV patients or adipogenic differentiation medium (ADM) and further subjected to differentiation and proliferation assay. The expression of adipogenesis genes was examined by real-time polymerase chain reaction to investigate the effect of lymph on ASCs. The level of adipogenic cytokines in the lymph was also evaluated. Results: The adipocytes were significantly larger in lymphedema fat tissue compared with that in normal fat tissues (P < 0.00). The adipogenesis of ASCs cultured in lymph was significantly enhanced compared with in ADM (P = 0.008) on day 10, suggesting that the adipogenesis of ASCs was promoted under the lymph-cultured environment. The expression of adipogenesis genes, peroxisome proliferator-activated receptor (P = 0.02), CAAT/enhancer-binding protein α (P = 0.008); fatty-acid binding protein (P = 0.004), and lipoprotein lipase (P = 0.003), was statistically elevated when the ASCs were cultured with lymph. The insulin content in lymph was statistically higher in lymph (P < 0.001) than in plasma. Conclusions: The adipogenesis of ASCs was promoted under the lymph-cultured environment with statistically increased adipogenesis genes of peroxisome proliferator-activated receptor, CAAT/enhancer-binding protein α, fatty-acid binding protein, and lipoprotein lipase. The excess lymph accumulated in the lymphedematous extremity contained a greater insulin/insulin-like growth factor-2. These adipogenic factors promoted the expression of early adipogenesis genes and led ASCs to undergo adipogenesis and differentiated into adipocytes. Clinical Relevance Statement: The accumulation of adipose tissue in the lymphedema region was contributed from the content of excess lymph
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