6,264 research outputs found
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
sj-docx-2-jad-10.1177_10870547231224088 – Supplemental material for Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling
No full textSupplemental material, sj-docx-2-jad-10.1177_10870547231224088 for Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling by Laila Tanana, Asam Latif, Prasad S Nishtala and Timothy F Chen in Journal of Attention Disorders</p
Online_Supplementary_Appendix_1_Original - Development and Psychometric Evaluation of a Questionnaire to Measure Attitudes Toward Perinatal Depression and Acceptability of Screening: The PND Attitudes and Screening Acceptability Questionnaire (PASAQ)
No full textOnline_Supplementary_Appendix_1_Original for Development and Psychometric Evaluation of a Questionnaire to Measure Attitudes Toward Perinatal Depression and Acceptability of Screening: The PND Attitudes and Screening Acceptability Questionnaire (PASAQ) by Sarira El-Den, Claire L. O’Reilly, and Timothy F. Chen in Evaluation & the Health Professions</p
sj-docx-1-jad-10.1177_10870547231224088 – Supplemental material for Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling
No full textSupplemental material, sj-docx-1-jad-10.1177_10870547231224088 for Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling by Laila Tanana, Asam Latif, Prasad S Nishtala and Timothy F Chen in Journal of Attention Disorders</p
Supplementary_131218 – Supplemental material for Integration of an electronic Drug Burden Index risk assessment tool into Home Medicines Reviews: deprescribing anticholinergic and sedative medications
No full textSupplemental material, Supplementary_131218 for Integration of an electronic Drug Burden Index risk assessment tool into Home Medicines Reviews: deprescribing anticholinergic and sedative medications by Lisa Kouladjian O’Donnell, Danijela Gnjidic, Timothy F. Chen and Sarah N. Hilmer in Therapeutic Advances in Drug Safety</p
Romance, op. 50
No full textMore Author/Title Info: Ludwig van Beethoven ; editions for double bass and piano by Timothy Cobb.
Uniform Title: Romances, violin, orchestra, op. 50, F major; arranged
Physical Description: 2 scores (10 pages) + 2 parts (4 pages) ; 28 c
Seminal contributions of Timothy J. Crow
No full text© The Author(s), 2025. Published by Cambridge
University Press. This is an Open Access article,
distributed under the terms of the Creative
Commons Attribution licence (http://
creativecommons.org/licenses/by/4.0), which
permits unrestricted re-use, distribution and
reproduction, provided the original article is
properly cited.We recall the life and work of Timothy J. Crow, whose contributions provided great insights into the pathophysiology of schizophrenia and continue to shape many questions in the field. We compile his key works relating to psychotic disorders, focusing on the trajectory of his theoretical stance. Our account is interlaced with our own interpretation of the evidence that influenced Crow's arguments over the years as well as his scientific method. Crow has had a significant impact on the neuroscience of schizophrenia. Many of his observations are still valid and several questions he raised remain unanswered to date.https://www.cambridge.org/core/journals/psychological-medicine/article/seminal-contributions-of-timothy-j-crow/25B0EA70F496D0D3351937E44ADDD45
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
Evaluating Research Impact through Open Access to Scholarly Communication
No full textScientific research is a competitive business – in order to secure funding, promotion and tenure researchers must demonstrate their work has impact in their field. To maximise impact researchers undertake high priority research, aim to get results first, and publish in the highest impact journals. The Internet now presents a new opportunity to the scholarly author seeking higher impact: s/he can now make their work instantly accessible on the Web through author self-archiving. This growing body of open access literature (coupled with new publishing models that make journals available for-free to the reader) maximises research impact by maximising the number of people who can read it, and making it available sooner. Open access also provides a new opportunity for bibliometric research. This thesis describes the relatively recent phenomenon of open access to research literature, tools that were built to collect and analyse that literature, and the results of analyses of the effect of open access and its effect on author behaviour. It shows that articles self-archived by authors receive between 50-250% more citations, that rapid pre-printing on the Web has dramatically reduced the peak citation rate from over a year to virtually instant and how citation-impact – now widely used for evaluation – can be expanded to include a new web metric of download impact
Management of orthopaedic infections: a practical guide/ [edited by] Antonia Chen.
No full textIncludes bibliographical references and index."Orthopaedic infections represent common, potentially devastating, and sometimes fatal complications that can occur after any surgery. Infections associated with orthopaedic trauma are especially prevalent, and there is an increasing incidence of bone infections linked to a greater number of joint arthroplasties being performed annually. Management of Orthopaedic Infections: A Practical Guide by renowned orthopaedic surgeon and researcher Antonia Chen is a practical clinical reference to assist clinicians in the diagnosis and treatment of challenging infections spanning the entire orthopaedic specialty"--Detection of Microbes in Orthopaedic Infections / Michael Henry, Andy O. Miller, and Barry D. Brause -- Antibiotics for Orthopaedic Infections / Alaina S. Ritter and Sandra B. Nelson -- Irrigation Solutions for Orthopaedic Infections / Michael Yayac, Samuel J. Clarkson, Craig Della Valle, and Javad Parvizi -- Surgical Wound Dressings after Treating Orthopaedic Infections / Patrick Moody and Bryan Springer -- Osteomyelitis / Martin McNally -- Treatment of the Septic Native Joint / Timothy L. Tan and Sommer Hammoud -- Management of Periprosthetic Joint Infection / Malcolm E. Dombrowski and Brian A. Klatt -- Infection after Fracture Fixation and Infected Nonunions / Arvind von Keudell and Michael J. Weaver -- Spine Infections / Caleb M. Yeung and Melvin C. Makhni -- Graft Infections / Robert Tisherman, Itamar Neto, Orr Limpisvasti, and Carola F. van Eck.1 online resourc
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