304,285 research outputs found
The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways
Copyright © 2009 Elsevier Ltd All rights reserved.Mei-Chi Chang, Li-Deh Lin, Chiu-Po Chan, Hsiao-Hua Chang, Lin-I. Chen, Hsueh-Jen Lin, Hung-Wei Yeh, Wan-Yu Tseng, Po-Shuen Lin, Chiu-Chun Lin and Jiiang-Huei Jenghttp://www.elsevier.com/wps/find/journaldescription.cws_home/30392/description#descriptio
Scaptodrosophila zebromyia Peng, Lin & Chen, 2022, nom. nov.
Scaptodrosophila zebromyia nom. nov. Scaptodrosophila zebrina Liu & Chen, 2018, hom. of S. zebrina (Bezzi, 1928). Distribution. China (Yunnan).Published as part of Peng, Hongen, Lin, Yong & Chen, Hongwei, 2022, Morphological and molecular evidence of eight new species of the genus Scaptodrosophila Duda (Diptera, Drosophilidae) from China, pp. 169-194 in Zootaxa 5093 (2) on page 186, DOI: 10.11646/zootaxa.5093.2.3, http://zenodo.org/record/590508
Messageria scalarioides subsp. donghiana Chen & Lin 2021
Messageria scalarioides donghiana Z.-Y. Chen & L.-W. Lin, n. ssp. Figures 1E–H, 2A Holotype: HBUMM 10058, a big cave in mountains between Fengshan County [Hechi City] and Leye County [Baise City], Guangxi Zhuang Autonomous Region, China, ex coll. Hao Yang, 2012. Paratypes: CZY/1, LLW/1, same data as holotype. Etymology. This name comes from the local Zhuang language “dongh”, which means “cave”. Diagnosis. This subspecies can be distinguished from the nominate subspecies by the larger shell and wider lower whorls and umbilicus. Also, the aperture of M. scalarioides donghiana n. ssp. and 1/8 whorl behind it evidently deviate from the axis and umbilicus. Measurements. H = 3.70 mm, W = 3.37 mm, D A = 1.89 mm (holotype). Vernacular name. Į梯Ħfiḏ洞Ë亚ḋ xuán tī chóng lèi luó dòng xué yà zhǒng Distribution. CHINA: Guangxi.Published as part of Chen, Zhe-Yu & Lin, Li-Wen, 2021, Notes on the genus Messageria Bavay & Dautzenberg, 1904, with descriptions of a new speciesand anew subspecies (Gastropoda: Caenogastropoda: Cyclophoroidea Alycaeidae), pp. 129-134 in Zootaxa 5067 (1) on pages 131-132, DOI: 10.11646/zootaxa.5067.1.9, http://zenodo.org/record/565663
Does Downloading PowerPoint Slides Before the Lecture Lead to Better Student Achievement?: Reply
This reply responds to a comment by Cannon (2011) that opens the debate on consistency of the effect of downloading PowerPoint slides before lectures on students’ exam performance. Cannon (2011) points out potential endogeneity problems in Chen and Lin (2008) and attempts to explore the unconditional mean effect of downloading PowerPoint slides for the full sample. In this reply, we firstly argue that the estimates in our original article are consistent since the effect of interest is the “conditional†treatment effect but not the unconditional mean effect. We provide explanations for our rationale of estimating the “conditional†treatment effect. Secondly, we propose a modified downloading variable to replicate Cannon’s analysis. Our results suggest that downloading PowerPoint slides before the exam does not produce a significant effect on absent students’ exam performance which is different from the results in Cannon (2011). Our analysis does support Cannon’s argument that students fixed effects are different across different attendance status.
Audit Partner Tenure, Audit Firm Tenure, and Discretionary Accruals: Does Long Auditor Tenure Impair Earnings Quality?
Inhibition of cyclooxygenase activity, platelet aggregation and thromboxane B₂ production by two environmental toxicants: m- and o-cresol
Chiu-Po Chan, Ho Yuan-Soon, Ying-Jen Wang, Wan-Hong Land, Lin-I Chen, Yi-Jane Chen, Bor-Ru Lin, Mei-Chi Chang, Jiiang-Huei Jen
Comment on Chen and Lin “Does downloading Powerpoint slides before the lecture lead to better student achievement?â€
Chen and Lin (2008) is an interesting attempt to measure the effect of students having access to PowerPoint slides before a lecture. They argue that such access leads to better learning outcomes as measured by higher exam marks. While their empirical results shed some light on students’ use of PowerPoint slides, I argue that they have not succeeded in isolating the treatment effect and the correlations cannot be interpreted as causal.
The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing
Lin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd
Chasing the China wind: a musical journey
In this documentary, Chen-Yu was to explore the musical memories of Post-90s Generation across Taiwan, Hong Kong, China, and the UK. This film presents that the way audiences engage with China Wind music reflects a constant negotiation of Chineseness that takes place in both the creation and consumption of music. In the meantime, popular music helps the post-90s audience creating their identities along the way to discovering and defining ‘selves’ while imagining themselves being or not being Chinese
[[alternative]]A Study on the Relation of the Citizen’s SubjectiveI Impression on the Spouses from Mainland China and Vietnam and Community Educational Policies in Shu Lin City in Taipei ounty.
[[abstract]]A Study on the Relation of the Citizen’s SubjectiveI Impression on the Spouses from Mainland China and Vietnam and Community Educational Policies in Shu Lin City in Taipei ounty.
Abstract
By:Chou chen- tsung Advisor:Lin en-chung
The purpose of this research is to understand the current situation of the citizen’s subjective impressions on the spouses from Mainland China and Vietnam in Shu Lin City. The survey is carried out by self-designed questionnaires. The parents of the students in 10 ele mentary schools of Shu Lin City were taken as samples, 1000 que stionnaires were released, in which 825 effective copies were responded and returned (reaching a 93.0% share of all return questionnaires). The methods for analyzing the data are adopted from SPSS Statistic Software, which includes avera
ges, standard deviation,t-test,ANOVA…etc to analyze.The main findings are as below:
1. The subjective impression of Shu Lin citizens on the
Mainland spouses tends to be “ordinary” to “slightly
good.”
2. Regarding the subjective impression of Shu Lin citizens
on the Mainland spouses, there is a significant
difference on the four out of six different variants,
which are gender, occupations, marital status, and their
experience of contacting Mainland China spouses.
3. The subjective impression of Shu Lin citizens on the
Vietnamese spouses tends to be “ordinary”to “slightly
good.”
4. Regarding the subjective impression of Shu Lin citizens
on the Vietnamese spouses, there is a significant
difference on the three out of six different variants,
which are occupations, marital status, and educational
background.
5. There is a significant difference on the citizens’
subjective impres sion between the spouses from Mainland
China and those from Vietnam.
“Focus Group Interview” was also practiced to enrich the study. Based on the research result, some suggestions regarding the effective community educational policies are proposed.
1.Publicize the positive impressions of Shu Lin citizens
toward the spouses from Mainland China and Vietnam.
2.More researches and studies should be done by th
government and the academic institutes in order to
facilitate the positive understanding.
3.Encourage the positive reports from the media which
should be carefully regulated by the government and the
non-gover nmental organizations.
4.For schools, enhance multicultural teaching
environment;for the government, host more multicultural
exhibitions about the spouses from Mainland and Vietnam.
5.Make good use of the resources from schools and
communities to popularize the idea of “multicultural
community educati on” as well as to facilitate the
integration of different races.
6.The spouses from Mainland and Vietnam should learn
actively and positively to adapt themselves to the
lifestyles of the ir family and the community; therefore,
they are able to gain more positive interaction and
feedback from the peoplein the community.
Key words: Mainland China spouses, Vietnamese spouses,
Transnational marriage, Subjective impression
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