1,072 research outputs found

    Assessment of Self-Archiving in Institutional Repositories: Depositorship and Full-Text Availability

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    This research evaluates the success of open access self-archiving in several well-known institutional repositories. Two assessment factors have been applied to examine the current practice of self-archiving: depositorship and the availability of full text. This research discovers that the rate of author self-archiving is low and that the majority of documents have been deposited by a librarian or administrative staff. Similarly, the rate of full-text availability is relatively low, except for Australian repositories. By identifying different practices of self-archiving, repository managers can create new strategies for the operation of their repositories and the development of archiving policies

    Factors to Assess Self-Archiving in Institutional Repositories

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    This paper proposes a group of factors that may be used to assess the success of open access self-archiving. It concentrates on self-archiving in institutional repositories. The authors emphasize the importance of examining content materials, particularly the availability of full text versus abstracts and the deposits archived by authors versus by others.Peer reviewe

    Superluminal and Instantaneous Physics

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    This book is a selection from the papers of the First International Conference on Superluminal Physics as New Fields of Research held at the University of New Mexico, Gallup Campus, USA, in July 2012. The editor have selected seven papers proposed by the following authors and co co-authors Kaizhe Guo Guo, Chongwu Guo Guo, Chen Jianguojianguo, Dong Jingfeng Jingfeng, Mi Haijiang Haijiang, Changwei Hu Hu, Yang Shijiashijia, Guli, and Fu Yuhua Yuhua

    Grassland canopy cover and aboveground biomass in Mongolia and Inner Mongolia: Spatiotemporal estimates and controlling factors

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    Temperate and semiarid grasslands comprise 80% of the land area on the Mongolian Plateau and environs, which includes Mongolia (MG), and the province of Inner Mongolia (IM), China. Substantial land cover/use change in the last few decades, driven by a combination of post-liberalization socioeconomic changes and extreme climatic events, has degraded these water-limited grassland's structure and function. Hence, a precise estimation of canopy cover (CC, %) and aboveground biomass (AGB, g m−2) is needed. In this study, we analyzed >1000 field observations with sampling during June, July and August (JJA) in 2006, 2007, 2010 and 2016 in IM and 2010–2012 and 2014–2016 in MG. The field sampling was stratified by the dominant vegetation types on the plateau, including the meadow steppe, the typical steppe, and the desert steppe. Here we used Moderate Resolution Imaging Spectroradiometer (MODIS) derived surface reflectance and vegetation indices optimized for low cover conditions to develop and test predictive models of CC and AGB using observed samples as training and validation data through rule-based regression tree models. We then used the predictive models to estimate spatially-explicit CC and AGB for the plateau over the last decade (2000–2016). Our study demonstrated the effectiveness of our predictive models in up-scaling ground observations to the regional scale across steppe types. Our results showed that model R2and RMSE for CC and AGB were 0.74 (13.1%) and 0.62 (85.9 g m−2), respectively. The validation R2and RMSE for CC and AGB were 0.67 (14.4%) and 0.68 (76.9 g m−2), respectively. The mean ± SD for CC and AGB were 24.9 ± 23.4% and 155.2 ± 115.2 g m−2, respectively. We also found that our scaled up estimates were significantly related to inter-annual climatic variability and anthropogenic drivers especially distance to urban/built-up areas and livestock density. In addition to their direct use in quantifying the spatiotemporal changes in the terrestrial carbon budget, results from these predictive models can help decision makers and rangeland managers plan sustainable livestock practices in the future

    Competences and responsibilities of social science data librarians: an analysis of job descriptions

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    This study examines job announcements for social science data librarians and professionals to identify trends in the profession. A collection of 167 job postings in 2005–2012 from the International Association for Social Science Information Services &Technology website was analyzed on the frequencies of term occurrence and co-occurrence in job qualifications and responsibilities. The study verifies that employers valued non-technical skills as heavily as technical skills, and detects dissimilar emphases of data activities for data librarians and non-librarian professionals: the former on data discovery and collection, and the latter on data analysis and preservation. An increasing requirement of data management planning was also found for data librarians.Peer reviewe

    NF-kappa B Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma

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    Epstein-Barr virus (EBV) expresses few viral proteins in nasopharyngeal carcinoma (NPC) but high levels of BamHI-A rightward transcripts (BARTs), which include long noncoding RNAs (lncRNAs) and BART microRNAs (miRNAs). It is hypothesized that the mechanism for regulation of BARTs may relate to EBV pathogenesis in NPC. Weshowed that nuclear factor-kappa B (NF-kappa B) activates the BART promoters and modulates the expression of BARTs in EBV-infected NPC cells but that introduction of mutations into the putative NF-kappa B binding sites abolished activation of BART promoters by NF-kappa B. Binding of p50 subunits to NF-kappa B sites in the BART promoters was confirmed in electrophoretic mobility shift assays (EMSA) and further demonstrated in vivo using chromatin immunoprecipitation (ChIP) analysis. Expression of BART miRNAs and lncRNAs correlated with NF-kappa B activity in EBV-infected epithelial cells, while treatment of EBV-harboring NPC C666-1 cells with aspirin (acetylsalicylic acid [ASA]) and the I kappa B kinase inhibitor PS-1145 inhibited NF-kappa B activity, resulting in downregulation of BART expression. Expression of EBV LMP1 activates BART promoters, whereas an LMP1 mutant which cannot induce NF-kappa B activation does not activate BART promoters, further supporting the idea that expression of BARTs is regulated by NF-kappa B signaling. Expression of LMP1 is tightly regulated in NPC cells, and this study confirmed that miR-BART5-5p downregulates LMP1 expression, suggesting a feedback loop between BART miRNA and LMP1-mediated NF-kappa B activation in the NPC setting. These findings provide new insights into the mechanism underlying the deregulation of BARTs in NPC and identify a regulatory loop through which BARTs support EBV latency in NPC

    Nonequilibrium transport of polyacrylamides correlated with pore-water velocity

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    Transport behavior of polyacrylamides (PAMs) in chernozem was investigated through the static equilibrium sorption experiment, column tests and modeling studies. In flow-through column studies, nonequilibrium sorption behavior of PAMs was described by a nonequilibrium mass transfer model combined with a Langmuir sorption model. Langmuir sorption isotherm parameters were obtained from the static sorption experiment and dispersion coefficients and pore velocities were obtained from breakthrough curves (BTCs) of Br-. Comparing with the traditional nonequilibrium mass transfer model with a linear isotherm, the developed nonlinear model predicts asymmetric sorption and desorption behavior. More importantly, we identified a strong linear relationship between the estimated first-order mass transfer rate coefficient and the pore velocity, which relates the empirical parameter mass transfer rate coefficients to the measurable system parameter of pore velocity. Our results suggest that mass transfer may limit the subsurface transport of PAMs and the lumped mass transfer rate coefficients are linearly correlated with flow velocities. The results also indicate that this one-site Langmuir sorption model may be applied to other contaminants’ transport during which the Langmuir mass transfer exists.M.S

    The influence of sex on the prognostic value of body mass index in non-metastasis renal cell carcinoma

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    Yangqin Zheng,1,* Lianmin Bao,2,* Jingfeng Chen,3,* Yue Pan,4 Qinquan Wang,4 Lianguo Chen,5 Xiaomin Gao61Department of Hematology, The Third Clinical Institute Affiliated to Wenzhou Medical University, People’s Hospital of Wenzhou, Wenzhou, Zhejiang 325006, People’s Republic of China; 2Department of Respiratory, Rui’an People’s Hospital, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325200, People’s Republic of China; 3Department of Anorectal Surgery, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui People‘s Hospital, Lishui, Zhejiang 323000, People’s Republic of China; 4Department of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325006, People’s Republic of China; 5Department of Clinical Pharmacy, Wenzhou People’s Hospital & The Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China; 6Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, People’s Republic of China *These authors contributed equally to this work Purpose: The prognostic value of obesity in patients with renal cell carcinoma (RCC) remains controversial. This study aimed to assess the sex-dependent prognostic role of body mass index (BMI) in patients with nonmetastatic RCC who underwent radical or partial nephrectomy.Patients and methods: We retrospectively analyzed 643 consecutive patients with nonmetastatic RCC who underwent curative nephrectomy in our center between 2004 and 2014. Associations among BMI, sex, overall survival (OS), cancer-specific survival (CSS), and metastasis-free survival (MFS) were analyzed.Results: Males were more likely to have a higher BMI than females (BMI as a categorical variable: P<0.001; BMI as a continuous variable: P=0.002). In men, a high BMI was significantly correlated with better 5-year OS, CSS, and MFS rates (P=0.001, 0.014, and 0.001, respectively), and multivariate analysis identified that a high BMI was independently associated with greater OS, CSS, and MFS (OS: hazard ratio [HR]=0.207, P=0.011; CSS: HR=0.225, P=0.005; MFS: HR=0.243, P=0.004). However, in women, there was no significant difference in 5-year OS, CSS, and MFS rates according to BMI (P=0.781, 0.812, and 0.538, respectively). Moreover, a high BMI was no longer independently associated with OS, CSS, or MFS (P=0.821, 0.832, and 0.801, respectively). Among patients with clear cell RCC, BMI was significantly associated with OS, CSS, and MFS only among men (all P<0.05) and not among women (all P>0.05).Conclusion: Among patients with nonmetastatic RCC, a high BMI was a favorable prognostic factor in males rather than females. Therefore, sex might influence the correlation between obesity and urological outcomes in nonmetastatic RCC.Keywords: renal cell carcinoma, body mass index, prognosis, se
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