377 research outputs found

    Multicenter Study of Presentation, Management, and Postoperative and Long-Term Outcomes of Septegenerians and Octogenerians Undergoing Gastrectomy for Gastric Cancer

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    Background: The optimal treatment strategy for elderly patients with gastric cancer is still controversial. This study aimed to assess the impact of age on short- and long-term outcomes after treatment for primary gastric cancer. Methods: From January 2004 to December 2014, a total of 507 patients underwent gastrectomy for gastric adenocarcinoma at two high-volume upper gastrointestinal (GI) centers. The patients were classified into three groups as follows: group A (patients ≤ 69 years old, n = 266), group B (patients 70–79 years old, n = 166), and group C (patients ≥ 80 years old, n = 75). Clinicopathologic characteristics as well as, short- and long-term outcomes were compared between the groups. Results: The patients in groups B and C had more comorbidities, whereas the younger subjects (group A) had more advanced tumor stages. Less extensive surgery was performed in the groups B and C. Older patients (age ≥ 70 years) had more postoperative medical complications. Moreover, group C had a higher postoperative mortality rate (8.1%) than group A (1.8%) or group B (1.9%). In the multivariable analysis, age older than 80 years (group C) was a negative independent factor for overall survival (OS) (hazard ratio [HR], 2.36) compared with group A, whereas group B seemed to have a comparable risk (HR, 1.37). Notably, the three groups did not show significant differences in disease-related survival (DRS). Conclusion: The data suggest that patients 70–79 years of age show a risk of postoperative death comparable with that of younger subjects. However, patients older than 80 years should be carefully selected for surgical treatment due to the increased risk of postoperative mortality

    Embedding spanning subgraphs into large dense graphs

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    In this thesis we are going to present some results on embedding spanning subgraphs into large dense graphs. Spanning Trees Bollob'as conjectured that if GG is a graph on nn vertices, delta(G)geq(1/2+epsilon)ndelta(G) geq (1/2 + epsilon) n for some epsilon>0epsilon > 0, and TT is a bounded degree tree on nn vertices, then TT is a subgraph of GG. The problem was solved in the affirmative by Koml'os, S'ark"ozy and Szemer'edi for large graphs. They then strengthened their result, and showed that the maximum degree of TT need not be bounded: there exists a constant cc such that TT is a subgraph of GG if Delta(T)leqcn/lognDelta(T) leq cn / log n, delta(G)geq(1/2+epsilon)ndelta(G) geq (1/2 + epsilon) n and nn is large. Both proofs are based on the Regularity Lemma-Blow-up Lemma Method. Recently, using other methods, it was shown that bounded degree trees embed into graphs with minimum degree n/2+Clognn/2 + C log n, where CC is a constant depending on the maximum degree of TT. Here we show that in general n/2+O(Delta(T)cdotlogn)n/2 + O(Delta(T) cdot log n) is sufficient for every Delta(T)leqcn/lognDelta(T) leq cn / log n. We also show that this bound is tight for the two extreme values of mm i.e. when m=Cm = C and when m=cn/lognm = cn / log n. Powers of Hamiltonian Cycles In 1962 P'osa conjectured that if delta(G)geqfrac23ndelta(G) geq frac{2}{3}n then GG contains the square of a Hamiltonian cycle. Later, in 1974, Seymour generalized this conjecture: if delta(G)geq(frack1k)ndelta(G) geq (frac{k-1}{k})n then GG contains the (k1)(k-1)th power of a Hamiltonian cycle. In 1998 the conjecture was proved by Koml'os, S'ark"ozy and Szemer'edi for large graphs using the Regularity Lemma. We present a ``deregularised" proof of the P'osa-Seymour conjecture which results in a much lower threshold value for nn, the size of the graph for which the conjecture is true. We hope that the tools used in this proof will push down the threshold value for nn to around 100 at which point we will be able to verify the conjecture for every nn.Ph.D.Includes bibliographical referencesIncludes vitaby Asif Jamshe

    Prediction of particle concentration profiles in binary-solid liquid fluidized bed

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    A simple mixing rule is presented here to predict the concentration profile of individual particle species in a binary-solid liquid fluidized bed from the information about the total solid concentration in the bed. Using the experimental data available in the literature, the applicability of this approach is demonstrated for the presence of different size particles in the bed. For the case of binary-solid fluidized bed showing layer inversion behavior, this simple mixing rule is capable of predicting the concentration of two species from the total solid concentration data of the bed.Corresponding Author: Dr. Mohammad Asif, Professor Department of Chemical Engineering, College of Engineering, King Saud University, P.O. Box 800, Riyadh-11421, Saudi Arabia. Email: [email protected]

    EpCAM

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    EpCAM

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    EpCAM

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    EpCAM

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    Semantic Question Classification Datasets

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    This is the datasets used in the following paper:Can Taxonomy Help? Improving Semantic Question Matching using Question TaxonomyPaper: http://aclweb.org/anthology/C18-1042If you use the dataset please cite the following paper:@InProceedings{C18-1042, author = "Gupta, Deepak and Pujari, Rajkumar and Ekbal, Asif and Bhattacharyya, Pushpak and Maitra, Anutosh and Jain, Tom and Sengupta, Shubhashis", title = "Can Taxonomy Help? Improving Semantic Question Matching using Question Taxonomy", booktitle = "Proceedings of the 27th International Conference on Computational Linguistics", year = "2018", publisher = "Association for Computational Linguistics", pages = "499--513", location = "Santa Fe, New Mexico, USA", url = "http://aclweb.org/anthology/C18-1042" } </div

    Prediction of tool temperature during machining of Ti-6Al-4V alloy with atomization-based cutting fluid spray system

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    Atomization-based cutting fluid (ACF) spray system is being sought as an alternative to cooling processes currently used for machining difficult-to-cut materials such as Ti-6Al-4V alloy. The ACF spray system generates a stream of monodispersed droplets of cutting fluid which then gets mixed in a high-velocity gas flow to form a focused axisymmetric jet of droplets. During machining, this jet is able to penetrate the small region of the tool-chip interface helping in lubrication and cooling of the interface. The advantage of the ACF spray system is that it requires very small amount of cutting fluid, which makes the system more energy efficient and environmentally friendly. It has been recently reported that ACF spray system improves machining performances including tool life and reduced temperature near the tool-chip interface in turning Ti-alloy. It is clear from these studies that the reduction in temperature and improvement in machining are mainly dependent on the interaction of the cutting fluid from the ACF spray system with the chip-tool interface. Therefore, it is imperative to have a physics-based understanding of the phenomena taking place at the interface that is responsible for the tool temperature reduction. In this study, a thermal model for the atomization-based cutting fluid (ACF) spray system is developed to predict the temperature of the cutting edge of the tool during machining of titanium alloys. In the model, film boiling is taken into account because of the high temperatures involved in turning of Ti-6Al-4V alloy. Due to film boiling a thin vapor film is formed between the heated tool surface and the droplet. Heat is being conducted away from the tool through this film. It is shown that the thermal model is able to predict the temperature reduction due to ACF spray cooling and the predicted temperature profile is comparable to the experimental results.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-08-01The student, Asif Tanveer, accepted the attached license on 2015-07-24 at 11:26.The student, Asif Tanveer, submitted this Thesis for approval on 2015-07-24 at 11:34.This Thesis was approved for publication on 2015-07-24 at 12:56.DSpace SAF Submission Ingestion Package generated from Vireo submission #8643 on 2015-09-29 at 15:06:54Made available in DSpace on 2015-09-29T21:08:27Z (GMT). No. of bitstreams: 2 TANVEER-THESIS-2015.pdf: 5086790 bytes, checksum: 282d1e7303cadf265c50b5554666401f (MD5) LICENSE.txt: 4209 bytes, checksum: bd7acda06591d0aee5bc8c7fd43c53f5 (MD5) Previous issue date: 2015-07-24Embargo set by: Seth Robbins for item 89602 Lift date: 2017-09-29T21:08:35Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 89602 on 2017-09-30T09:15:32Z
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