5,879 research outputs found
MSJ794063_supplementary_material – Supplemental material for Over three decades study populations in progressive multiple sclerosis have become older and more disabled, but have lower on-trial progression rates: A systematic review and meta-analysis of 43 randomised placebo-controlled trials
Supplemental material, MSJ794063_supplementary_material for Over three decades study populations in progressive multiple sclerosis have become older and more disabled, but have lower on-trial progression rates: A systematic review and meta-analysis of 43 randomised placebo-controlled trials by Richard S Nicholas, Erika Han, Joel Raffel, Jeremy Chataway and Tim Friede in Multiple Sclerosis Journal</p
Do dolphins benefit from nonlinear mathematics when processing their sonar returns?
An interview with author Tim Leighton about the paper
Opportunities for linking young surveyors across professional surveying member organisations and FIG
Tim Di Muzio on 'Sabotage'
In a series of essays published in 2013 and 2014 on capitaspower.com, political economist Tim Di Muzio explored the concept of ‘sabotage’ as it applies to capitalist power. I recently rediscovered these essays and was so impressed by them that I have reposted them here as a single piece.
About the author: Tim Di Muzio is a researcher at the University of Wollongong. He is the author of numerous books, including Debt as power, Carbon capitalism, and The 1% and the Rest of us
1996-1997 Tim Gautreaux
Tim Gautreaux is the author of three novels and two earlier short story collections. His work has appeared in The New Yorker, The Best American Short Stories, The Atlantic, Harper’s, and GQ. After teaching for thirty years at Southeastern Louisiana University, he now lives, with his wife, in Chattanooga, Tennessee. (Photo credit: Randy Bergeron)https://egrove.olemiss.edu/grisham_res/1023/thumbnail.jp
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An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection
Adaptive seamless phase II/III clinical trial designs allowing treatment selection at an interim analysis have gained much attention because of their potential benefits compared to more conventional drug development programmes with separate trials for individual phases. A scenario of particular interest is that in which the final outcome in the trial is based on long-term follow-up, but the interim analysis can only realistically be based on early (short-term) outcomes. A new software package (asd) for the statistical software R implements simulations for designs of this type, in addition to the simpler scenario where treatment selection is based on the definitive (final) outcome. The methodology is briefly described and two examples of proposed trial designs in progressive multiple sclerosis are provided, with R code to illustrate application of the methodology
First person - Tim Petzold
First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Tim Petzold is first author on ‘ Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification’, published in BiO. Tim conducted the research described in this article while a PhD student in Julien Bertrand's lab at the Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Switzerland. He is now a postdoc in the lab of Holger Gerhardt at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, investigating developmental biology – previously his focus was on how blood stem cells develop and now it has shifted to how the vascular system develops
Tim Seibles, 40th Annual ODU Literary Festival
Tim Seibles is the author of several poetry collections including Hurdy-Gurdy, Hammerlock, Buffalo Head Solos, and Fast Animal, which was a finalist for the 2012 National Book Award. In 2013 he received both the Pen Oakland Josephine Miles Award for poetry and an honorary Doctorate of Humane Letters from Misericordia University for his literary accomplishments. His latest collection, One Turn Around the Sun, has just been released. Tim is the current Poet Laureate of Virginia and is a Professor of English at Old Dominion University where he teaches literature as well as classes in the MFA in writing program
Tim Seibles, 39th Annual ODU Literary Festival
Tim Seibles is the author of several poetry collections including Hurdy-Gurdy, Hammerlock, Buffalo Head Solos, and Fast Animal, which was a finalist for the 2012 National Book Award. In 2013 he received both the Pen Oakland Josephine Miles Award for poetry and an honorary Doctorate of Humane Letters from Misericordia University for his literary accomplishments. His latest collection, One Turn Around the Sun, has just been released. Tim is the current Poet Laureate of Virginia and is a Professor of English at Old Dominion University where he teaches literature as well as classes in the MFA in writing program
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