343 research outputs found
Microfinance Impact Evaluation: A Managerial Perspective
No full textThe objective of this concept note was to introduce Impact Evaluation and highlight its need and importance during these turbulent times. As it turns out that Impact Evaluation holds promise to a host of benefits to the MFIs ranging from consumer insights to launching of new products and services and from better reporting standards to performance measurement. It will gain further prominence in coming days as focus of various stakeholders undergoes drastic shift towards social performance and understanding the consumer behavior. Not only it will be a strategic exercise but it will be adopted as a risk mitigation tool for identifying loopholes and appropriate measures to plug them.Microfinance, Impact Evaluation,
Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors
No full textThe present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, and 41 were chosen for the synthesis based on the results of the in silico screening. Each of the synthesized compounds was tested for its in vitro antibacterial and antifungal activities using a variety of strains. All the compounds showed antibacterial properties against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus pyogenes) as well as Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). Most of the compounds either had a higher potency than chloramphenicol or an equivalent potency to ciprofloxacin. Compounds 29 and 33 were effective against all the bacterial and fungal strains. Finally, the 1,2,3,4-tetrahydropyrimidine-2-thiol derivatives with a 6-chloro-2-(chloromethyl)-1H-benzo[d]imidazole moiety are potent enough to be considered a promising lead for the discovery of an effective antibacterial agent
Erratum: Space charge limited release of charged inverse micelles in non-polar liquids (Phys. Chem. Chem. Phys. (2016) 18 (19289–19298) DOI: 10.1039/C6CP03544B)
No full textThe authors would like to clarify that Manoj Prasad is the corresponding author of the manuscript with email address: [email protected]. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.</p
RECTIFIED DIFFERENTIAL CRYPTANALYSIS OF 16 ROUND PRESENT
No full textRECTIFIED DIFFERENTIAL CRYPTANALYSIS OF 16 ROUND PRESENT
Manoj Kumar , Pratibha Yadav and Meena Kumari
SAG, DRDO, Metcalfe House, Delhi-110054, India
ABSTRACT
In this paper, we have suggested rectifications in differential cryptanalysis of ultra-lightweight block cipher PRESENT reduced to 16 rounds. We have shown that proposed differential attack by Wang [3] on 16 round PRESENT can recover at the most 30 subkey bits, although the author has claimed to recover 32 bits of subkey for last two rounds. We have also computed data complexity and success probability for recovering 30 subkey bits accordingly by the differential attack on 16 round PRESENT.
KEYWORDS
Lightweight block cipher, differential cryptanalysis, PRESEN
Manoj Basur Koyekti Chhotogalpo : Deshbhag, Sampradayik Danga O Hindu-Musalman Somporker Antorboyan/ মনোজ বসুর কয়েকটি ছোটগল্প : দেশভাগ, সাম্প্রদায়িক দাঙ্গা ও হিন্দু-মুসলমান সম্পর্কের অন্তর্বয়ান
No full textThe forties are very significant in Bengali literature. The partition, riots and the crisis of refuges life are reflected in every form of literature. The impact of partition and ritos is reflected a little more in the stories. The brutality of the riots, violence and hatred, and the pain of partition have been reflected in the writings of many story taller’s. Manoj Basu is one of the few storytellers who embodied the riots and partition in the pens of the fortis and fifties. Compassion for the homeland and relatives, that is, the people, is the main feature of Manoj Basu\u27s literature. Just as there is a thorough picture of how public life was disrupted in the Hindu-Muslim riots and the partition after independence. Manoj Basu\u27s stories also show the picture of people coming together, forgetting the memories of the riots and partition. The riots created districts between the two Nations, Hindus and Muslims, and partition increased it. Therefor after partition, communal classes and unrest increased even more. storyteller Manoj Basu has sympathetically portrayed the people in danger during riots and partition in his stories after independence. And so we see the harmony of Hindu-Muslim relations in his stories. He believed that oneday all the darkness would pass, the storm would stop and light would shine again, all the unrest would end. That is why he has faith in people and he wanted to protray that in his stories. In stories like \u27Hindu Muslim Danga\u27, ‘Dangar Ekti Kahini\u27, ‘Dangar Daag\u27, ‘Hindu Muslim’, ‘Simanta\u27, ‘Epar Opar\u27, ‘Tanter Maku\u27 etc. The author has protrayed the picture of Hindu Muslim relations during the riots and partitions during the contemporary and post partition period with experience. His stories have become an intertextual account of Hindu Muslim relations. Manoj Basu wanted to show the good heart of a person can never die. Even if riots and partition temporary separate people, it can never be permanent. When the fire of hatred and jealousy dies down, faith in each other returns because people always stand by each other losing faith in people is a sin— this message of hope is echoed in Manoj Basu\u27s stories
Development of validated RP-HPLC method for the simultaneous estimation of atenolol and chlorthalidone in combine tablet dosage form
No full textA RP-HPLC method for the estimation of ATN (Atenolol) and CTN (chlorthalidone) in combined dosage form was developed using Comosil RP-C18 (4.6 x 250mm, 5m) in an gradient mode with mobile phase comprising of Methanol: Water (pH 3 using OPA) The flow rate was 1 mL/ min and effluent was monitored at 226.0 nm. The retention times were found to be 2.2 min for ATN and 3.36 min for CTN. The assay exhibited a linear dynamic range of 40- 200 g/mL for ATN and 10- 50 g/mL for CTN. The calibration curves were linear (r 2 = 0.999 for ATN and r 2 = 0.999 for CTN) over the entire linear range. Mean % recovery was found to be 99.78 % for ATN and 99.30 % for CTN with % RSD was NMT 2 for both estimations which fully agrees with system suitability which is in good agreement with labeled amount of formulation. The % RSD for Intra- Day and Inter-Day Precision was NMT than 2 for both the drugs. The developed method was validated as per ICH guideline
DETERMINATION OF ATORVASTATIN CALCIUM IN PHARMACEUTICAL FORMULATIONS BY REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
No full textA simple, sensitive and reproducible reverse-phase high performance liquid chromatographic (RP-HPLC) method has been developed for the quantitative estimation of Atorvastatin calcium in the pharmaceutical formulations. Chromatographic separation was achieved on a 250 × 4.6 mm, 5μ, Waters symmetry column. The flow rate was 1ml/min and eluent was monitored by absorbance at 246 nm using a mixture of Methanol and Acetonitrile (pH 3.
Development of stability indicating assay method for estimation of Ibuprofen and Famotidine in combined dosage form in tablet
No full textA simple, precise, accurate, simultaneous stability indicating RP-HPLC method for the estimation of IBU (Ibuprofen) and FMT (Famotidine) in combined dosage form was developed using Grace RP-C18 (4.6 x 250mm, 5m) in an gradient mode with mobile phase comprising of Methanol: Water (pH 2.5 using OPA) The flow rate was 0.7 mL/ min and effluent was monitored at 240.0 nm. The retention times were found to be 6.68 min for IBU and 1.76 min for FMT. The assay exhibited a linear dynamic range of 30- 150 g/mL for IBU and 1- 5 g/mL for FMT. The calibration curves were linear (r 2 = 0.994 for IBU and r 2 = 0.997 for FMT) over the entire linear range. Mean % recovery was found to be 99.82 % for IBU and 99.91 % for FMT with % RSD was NMT 2 for both estimations which fully agrees with system suitability which is in good agreement with labeled amount of formulation. The % RSD for Intra- Day and Inter-Day Precision was NMT than 2 for both the drugs. The developed method was validated as per ICH guideline
Corporate Governance, Competition and Firm Performance: Evidence from India.
No full textThe aim of this paper is to show the interaction effect of product market competition and corporate governance variables on firm performance. While the linkage between internal governance mechanism and firm performance is well established in several studies, the interaction between internal and external governance mechanism has received scanty attention in emerging market economies. Here we have shown the independent and interaction effect of ownership and competition variable on firm productivity. Contrary to conventional wisdom, we document that competition has in reality become a discernible force in developing economies. The econometric modelling result shows while the standalone effect of ownership variable on productivity is mostly insignificant, there is a strong positive interaction effect with competition variables.
Phytochemical Screening & in vivo Fertility Enhancing Activity (Aphrodisiac) of Abutilon indicum Roots on Male Wistar Rats
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