1,175 research outputs found

    Polymeric micelles and the Dy-166/Ho-166 generator: A study of the loading mechanism of Dy/Dy-166 and Ho-166 into PCL-b-PEO polymeric micelles for imaging and cancer treatment

    No full text
    A radioisotope used in radionuclide therapy is Holmium-166 (Ho-166). The treatment effectiveness of Ho-166 could be improved by the use of a so called in vivo Dysprosium-166(Dy-166)/Ho-166 generator. The application of this generator is hindered by an effect called internal conversion (IC). This affect can arise after the decay of Dy-166 to Ho-166, which can cause separation of Ho-166 from its carrier.Polymeric micelles might form a solution in the application of the Dy-166/Ho-166 generator in radionuclide therapy. The main goal of this thesis was to investigate and understand the loading mechanism of metallic species and polymeric micelles with a focus on the loading of Dy/Dy-166 and Ho-166. It was found that it was not effective to load metallic species (Dy/Dy-166) as free ions or as solid precipitates. Loading metallic species as aqueous hydroxides showed to be crucial for achieving a good loading and high stability. The second goal was to study if polymeric micelles were able to retain Ho-166 inside their core under the effects of internal conversion. No additional losses of Ho-166 were found when Dy/Dy-166 and Ho-166 were loaded into the micelles. It was concluded that the PCL-PEO micelles prevented the loss of Ho-166 under internal conversion effects.Applied Science

    Dy Tien Nguyen oral history interview and transcript

    No full text
    This recording and transcript form part of a collection of oral history interviews conducted by the Chao Center for Asian Studies at Rice University. This collection includes audio recordings and transcripts of interviews with Asian Americans native to or living in Houston.Dy Tien Nguyen was born in Hai Duong, Vietnam and is the oldest of ten siblings. His family moved from village to village in the midst of The First Indochina War and later migrated to South Vietnam when the country divided in 1954. After high school, he enlisted in the Vietnamese Army Military Medical School. After his training, he started his fellowship in San Antonio for additional training in general surgery. When the Vietnam War ended, Nguyen became a refugee and chose to stay in the US and switch to anesthesiology. After 26 years at MD Anderson as an academic physician, he now spends his time teaching the Vietnamese language and tai chi

    beta-delayed proton decays and spin assignments for Tb-140, Dy-141 and Dy-143

    No full text
    The proton-rich isotopes Tb-140 and Dy-141 were produced via the fusion evaporation reaction Ca-40+ Cd-106. Their beta-delayed proton decays were studied by p-gamma coincidence in combination with a He-jet tape transport system, and half-lives, proton energy spectra, gamma-transitions following the proton emission, as well as beta-delayed proton branching ratios to the low-lying states in the grand-daughter nuclei were determined. Comparing the experimental data with statistical model calculations, the ground-state spins of Tb-140 and Dy-141 were found to be consistent with 7 and 9/2, respectively. The configuration-constrained nuclear potential energy surfaces (NPES) of Tb-140 and Dy-141 were calculated using the Woods-Saxon-Strutinsky method, which suggest the ground-state spins and parities of Tb-140 and Dy-141 to be 7(+) and 9/2(-), respectively. In addition, the configuration-constrained NPES of Dy-143 were calculated, which predict a 1/2(+) ground state and a 11/2(-) isomer with excitation energy of 198 keV. These findings are consistent with our previous experimental data on Dy-143 reported in Eur. Phys. J. A 16, 347 (2003).Physics, NuclearPhysics, Particles & FieldsSCI(E)3ARTICLE137-402

    Direct numerical simulation of turbulent Couette-Poiseuille flow with zero skin friction

    No full text
    The near-wall scaling of mean velocity U(y) is addressed for the case of zero skin friction on one wall of a fully turbulent channel flow. The present DNS results can be added to the evidence in support of the conjecture that U is proportional to √yw in the region just above the wall at which the mean shear dU/dy = 0

    NdFeB 磁体的Dy 热扩渗过程及其矫顽力提高机制

    Full text link
    Thermal diffusion of heavy rare earths is an important technology for preparation of the sintering NdFeB magnets with high-performance and low-cost. However, the stability of diffusing process is lower and the mechanism of Dy diffusion is still unclear, which has become a bottleneck affecting the large-scale application of the technology. In this work, commercial 35M magnets prepared with recycled materials was used as original magnets. A novel home-made DyF3 coating, which can prepare uniform and adhesive Dy coating layer on the surface of the NdFeB magnet, was employed into Dy diffusion treatment. The results show that the DyF3 coating has advantages of quick-drying, good adhesion and uniform coating, which effectively improved the stability of thermal diffusion process. An optimal Dy diffusion process was obtained when the thermal diffusion was conducted at 900С for 10 h. The coercivity of the magnet obtained by the optimal process reached to 1710.2 kA/m, increased by 37.9%, with a negligible decrease of remanence. The analysis of microstructure indicates that during the thermal diffusion, Dy element diffused along the grain boundary into the magnet and a Dy-rich shell layer (Nd, Dy)2Fe14B was formed around the main crystal phase. The mechanism of coercivity improvement of the magnets were discussed. Higher magnetic anisotropy field Dy-rich shell layer and the continuous and clear Nd-rich phase at the grain boundary resulted in a significant increase in the coercivity of the magnet
    corecore