32,767 research outputs found
Ben jing xu shu yao
[V.1-6]. 本經疏證 -- [v.7-9]. 本經續疏 -- [v.9-12]. 本經序疏要.[V.1-6]. Ben jing shu zheng -- [v.7-9]. Ben jing xu shu -- [v.9-12]. Ben jing xu shu yao.鄒澍學 ; 常州常年醫局校栞. 本經續疏 : 六卷 / 鄒澍學 ; 胡杰校栞. 本經序疏要 : 八卷 / 鄒澍學 ; 許恩溥校栞.綫裝 .框16.3x12.7公分, 11行22字, 小字雙行同. 白口, 左右雙邊, 單黑魚尾. 版心上鐫題名, 中鐫卷次, 下鐫葉次.第一冊書名頁刻"鄒閏安先生本經疏證十二卷續疏六卷本經序疏要八卷" ; 又有紅色戳記"常州麟玉山房發兌"《本經序疏要》卷八末刻"常郡韓文煥齋鐫". 並有湯用中道光己酉[1849]跋.《中國中醫古籍總目》(02456)著錄.鈐"莊兆祥印", "莊兆祥".Xian zhuang .Kuang 16.3 x 12.7 gong fen, 11 hang 22 zi, xiao zi shuang hang tong. Bai kou, zuo you shuang bian, dan hei yu wei. Ban xin shang juan ti ming, zhong juan juan ci, xia juan ye ci.Detailed notes in vernacular field only.Detailed notes in vernacular field only.Detailed notes in vernacular field only.Zou Shu xue ; Changzhou Chang nian yi ju jiao kan. Ben jing xu shu : liu juan / Zou Shu xue ; Hu Jie jiao kan. Ben jing xu shu yao : ba juan / Zou Shu xue ; Xu Enpu jiao kan.Qian "Zhuang Zhaoxiang yin", "Zhuang Zhaoxiang"
La chang xi : hui bei ji
1. 二人轉 : 豬八戒拱地 -- 2. 拉場戲 : 回盃記.1. Er ren zhuan : Zhubajie gong di -- 2. La chang xi : hui bei ji.Performers: 吉林省民間藝術團.Live recording."First copy"--Spine label.Electronic reproduction from Rulan Chao Pian VHS collection.Sung in Chinese.Performers: Jilin Sheng min jian yi shu tuan
Liu shu chang jian
許愼說文 ; 趙宧光長箋.框21.7x14.8公分, 10行20字, 小字雙行同, 白口, 左右雙邊, 單白魚尾, 版心上鐫小題, 中鐫卷次, 下鐫葉次.出書年據後序.卷首分上, 下卷.前有萬曆丙午[1606]趙宦光自序, 崇禎辛未[1631]後序.卷前附: 六書長箋 : 七卷 / 趙宧光.Library's copy: the library keeps vol.1-31 only, juan 98-100 missing.Xu Shen shuo wen ; Zhao Yiguang chang jian.Kuang 21.7x14.8 gong fen, 10 hang 20 zi, xiao zi shuang hang tong, bai kou, zuo you shuang bian, dan bai yu wei, ban xin shang juan xiao ti, zhong juan juan ci, xia juan ye ci.Chu shu nian ju hou xu.Juan shou fen shang, xia juan.Qian you Wanli bing wu [1606] Zhao Huanguang zi xu, Chongzhen xin wei [1631] hou xu.Juan qian fu: Liu shu chang jian : qi juan / Zhao Yiguang
Han lin shuo chang zhuan ji dai
Live recording.Possibly reproduced from other commercial recording or radio broadcast (Pending for review)Electronic reproduction from Rulan Chao Pian Betamax collection.Performing group: 漢霖民俗說唱藝術團.Sung in Chinese.Performing group: han lin min su shuo chang yi shu tuan
Liu Yi-chang wen ku mu lu
Ben shu mu wei xiang gang zhi ming wen xue zuo jia liu yi chang di yi ci juan zeng gei xiang gang zhong yang tu shu guan de shu kan de mu lu. qi nei rong da bu fen wei xiang gang wen xue zhu zuo yi ji yi bu fen hai wai hua wen wen xue zuo pi
sj-docx-1-aut-10.1177_13623613231223626 – Supplemental material for Factors mediating pre-existing autism diagnosis and later suicidal thoughts and behaviors: A follow-up cohort study
Supplemental material, sj-docx-1-aut-10.1177_13623613231223626 for Factors mediating pre-existing autism diagnosis and later suicidal thoughts and behaviors: A follow-up cohort study by Jung-Chi Chang, Meng-Chuan Lai, Shu-Sen Chang and Susan Shur-Fen Gau in Autism</p
Higher Familial Loading Associates with Impaired Flush Response to Niacin Skin Patch among Schizophrenia Patients and Their Nonpsychotic Relatives
目的:在先前的研究中,我們曾報告在精神分裂症患者及其家庭成員中之異常菸鹼酸皮膚貼片紅腫反應有家族聚集之現象。然而,尚未有研究探討此異常之紅腫反應是否與精神分裂症之家族負荷有關。本研究是比較兩類精神分裂症家庭之病人及親屬的菸鹼酸紅腫反應,即多發性家庭(家庭中至少有一對發病手足)及單發性家庭(核心家庭中僅有一位罹病成員)。
方法:研究個案為來自多發性家庭的病人及其一等親屬(311位罹患精神分裂症或分裂精感性疾患之指引個案,180位雙親與52位無病手足)、來自單發性家庭的病人及其一等親屬(176位指引個案,260位雙親與80位無病手足),以及90位正常對照個案。我們使用三種不同濃度之菸鹼酸貼片(0.001M、0.01M與0.1M),貼附於前臂皮膚上五分鐘,於移去貼片後五、十及十五分鐘時為紅腫程度評分(0,1,2及3分)。
結果:和來自單發性家庭的對比個案相較下,多發性家庭病人及其非精神病性之一等血親屬均有較為減弱之紅腫反應,而且此差異在使用濃度0.1M之菸鹼酸貼片時最為顯著,在此濃度下,來自多發性家庭的23-57%病人、27-56%父母及19-40%無病手足未呈現紅腫反應,相較之下,單發性家庭的對應個案未呈現紅腫反應之比例則分別為5-29%、3-17%及5-18%,而正常對照則是0-30%。此皮膚紅腫反應在三組之間存在一梯度:正常對照組最強,其次為單發性家庭成員,多發性家庭成員之反應為最弱。
結論:來自多發性家庭之精神分裂症病人及其無病親屬有較高之家庭負荷,同時菸鹼酸皮膚貼片紅腫反應亦更為異常。此項發現有助於未來精神分裂症遺傳病因之研究。Objective: We previously reported familial aggregation in flush response to niacin skin patch among schizophrenia patients and their nonpsychotic relatives. However, little is known whether this abnormal niacin response is associated with familial loading for schizophrenia. This study compared niacin response in subjects from families with a sib-pair with schizophrenia (multiplex families) and those from families with only one member affected (simplex families).
Method: Subjects were schizophrenia patients and their first-degree relatives from multiplex families (311 probands with schizophrenia or schizoaffective disorder, 180 parents, and 52 non-affected siblings) and simplex families (176 schizophrenia probands, 260 parents, and 80 non-affected siblings) as well as 90 healthy comparison subjects. Niacin patches of three concentrations (0.001M, 0.01M, 0.1M) were applied to the forearm skin, and the flush response was rated at 5, 10 and 15 minutes, respectively, with a 4-point scale.
Results: More blunted response to topical niacin was shown in schizophrenia probands and their nonpsychotic relatives from multiplex families than their counterparts from simplex families. The greatest degree of differentiation between groups were revealed using 0.1M of niacin, with nonflush response in 23-57% of probands, 27-56% of parents, and 19-40% of siblings from multiplex families in contrast to 5-29%, 3-17% and 5-18% of their counterparts from simplex families, respectively, as well as in 0-30% of normal controls.
Conclusions: Flush response to skin niacin is more impaired in schizophrenia patients as well as their relatives from families with higher loading for schizophrenia. This finding might be useful for future genetic dissection of schizophrenia.口試委員會審定書 i
口試委員會審定書(英文)ii
誌謝 iii
中文摘要 iv
英文摘要 v
1. Introduction 1
1.1 Background 1
1.1.1 Impaired niacin flush response in schizophrenia 1
1.1.2 Niacin subsensitivity as a potential genetic indicator for schizophrenia 2
1.1.3 The familial-sporadic distinction in etiological dissection of schizophrenia 3
1.2 Study Design and Aims 4
2. Method 6
2.1 Subjects 6
2.1.1 Multiplex families 6
2.1.2 Simplex families 6
2.1.3 Healthy comparison subjects 7
2.1.4 Inclusion and exclusion criteria 7
2.2 Interview Instruments and Diagnostic Procedures 8
2.3 Niacin Skin Test 9
2.3.1 Protocol 9
2.3.2 Reliability 9
2.3.3 Definition of nonflushness and volumetric niacin response 15 (VNR15) 9
2.4 Data Analysis 10
2.4.1 Statistical models 10
2.4.2 False discovery rate and effect sizes 11
3. Results 12
3.1 Subject Characteristics 12
3.2 Flush Score Distribution 12
3.3 Proportion of Nonflushness 12
3.4 Mean Niacin Response Scores 13
3.4.1 Volumetric niacin response 14
3.4.2 Comparisons with normal controls 14
4. Discussion 15
4.1 Range of Flush Response 15
4.1.1 Response at the lower end 15
4.1.2 Response at the upper end 16
4.2 Discrimination between Groups 16
4.2.1 Effects of concentration and time 16
4.2.2 Choice of response indexes 17
4.2.2.1 Original continuous scores and dichotomous flush response 17
4.2.2.2 Volumetric niacin response 15 (VNR15) 18
4.3 Strengths of Current Study 18
4.4 Limitations 19
4.5 Implications 21
4.6 Conclusions 22
Reference 2
Yan chang
沈寂著.電影文學劇本.原名: 鹽場.本電子書乃根據《香港版權條例(第528章)》而複製, 並只可在大學圖書館系統內的獨立電子書系統上使用.Shen Ji zhu.Ben dian zi shu nai gen ju "Xianggang ban quan tiao li (Di 528 zhang)" er fu zhi, bing zhi ke zai da xue tu shu guan xi tong nei de du li dian zi shu xi tong shang shi yong.Dian ying wen xue ju ben.Yuan ming: Yan chang
Kurt Vogel, Chin Chang Suan Shu ; Neun Bücher Arithmetischer Technik
Itard Jean. Kurt Vogel, Chin Chang Suan Shu ; Neun Bücher Arithmetischer Technik. In: Revue d'histoire des sciences et de leurs applications, tome 22, n°3, 1969. pp. 278-279
Kurt Vogel, Chin Chang Suan Shu ; Neun Bücher Arithmetischer Technik
Itard Jean. Kurt Vogel, Chin Chang Suan Shu ; Neun Bücher Arithmetischer Technik. In: Revue d'histoire des sciences et de leurs applications, tome 22, n°3, 1969. pp. 278-279
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