16,398 research outputs found
La population de Chang-Haï
No full textR. Ch. La population de Chang-Haï. In: Annales de Géographie, t. 41, n°233, 1932. p. 553
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
Full text linkThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
From the Great Void to Moral Practice: Ira Kasoff’s Systemic Reconstruction of Chang Tsai’s Ontological Ch’i in Cosmology, Human Nature, and Sagehood
No full textThis paper examines Ira E. Kasoff’s systemic interpretation of Chang Tsai’s Neo-Confucianism in his The Thought of Chang Tsai (1020–1077), focusing on Kasoff’s reconstruction of Ch’i (qi, 气) as the ontological foundation of Chang’s philosophy. Through a trichotomous translational strategy—distinguishing between “Ch’i”, “ch’i”, and “qi”—Kasoff systematically integrates Chang’s cosmology, human nature, and ethics into a coherent framework. He argues that Ch’i (e.g., Great Void, taixu, 太虚) serves as the primordial substance underlying all existence, while ch’i and qi explain the generation of phenomenal forms and moral agency. Kasoff highlights how Chang’s Ch’i-centric ontology refutes Buddhist illusionism and Daoist non-being, positing yin–yang interactions as the self-generative mechanism of the cosmos. Central to Kasoff’s analysis is Chang’s dual-nature theory of heavenly nature (天地之性, as the inherent goodness of Ch’i) and physical nature (气质之性, as the individualized limitations of ch’i); Kasoff demonstrates how Chang’s emphasis on learning (xue, 学) aims to transform nature and restore heavenly nature, culminating in sagehood as the realization of cosmic harmony. Additionally, by contrasting Chang’s Ch’i-based system with Cheng-Zhu Neo-Confucianism, Kasoff underscores its originality—a dynamic, materialist ontology that bridges metaphysics and ethics
Ecotypic variation of Imperatia cylindrica populations in Taiwan: II. Physiological and biochemical evidence
No full textParaquat-induced chlorophyll loss in rice leaves: evidence for the involvement of light and photosynthetic elcetron transport
No full textEstimating genotype relative risks in case-parental control studies: an optimal weighting approach
No full textSafety and immunogenicity of a Diphtheria, Tetanus, and acellular pertussis-inactivated poliovirus vaccine/Haemophilus Influenzae type B combination Vaccine administered to Taiwanese infants at 2, 4 and 6 months of age
No full textEfficacy of light therapy on nonseasonal depression among elderly adults: a systematic review and meta-analysis [Corrigendum]
No full textCH Chang, CY Liu, SJ Chen, HC Tsai. Neuropsychiatr Dis Treat. 2018;14:3091–3102.The authors have advised that they listed the second affiliation in the author list of the paper incorrectly. The current affiliation number 2 “Department of Psychiatry & Brain Disease Research Center, China Medical University Hospital, Taichung, Taiwan” should instead appear as “An Nan Hospital, China Medical University, Tainan, Taiwan”.Read the original articl
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