24 research outputs found
Occurrence of Lignans in the Orchidaceae Plants Lusia volucris and Bulbophyllum triste
No full textDepartment of Chemistry, University College of Science, 92 Acharya Prafulla Chandra Road, Calcutta-700 009
Manuscript received 17 March 1993, accepted 19 July 1993
Occurrence of Lignans in the Orchidaceae Plants Lusia volucris and Bulbophyllum triste
Study of Chemical Oscillation in a Mixed Substrate System of Gallic Acid and Acetone using Cerium(IV) Ions as Catalyst and a Comparative Study of the Catalytic Activity of Cerium(IV) Ions and Ferroin
No full textDepartment of Chemistry, University College of Science, 92 Acharya Prafulla Chandra Road, Calcutta-700 009
Manuscript received 9 August 1996, revised 21 February 1997, accepted 25 February 1997
Chemical oscillation has been studied using gallic acid and varying amounts of acetone as the mixed organic substrate both visually and potentiometrically side by side by the batch method. CeIV ions have been used as catalyst and sulphuric acid as the medium. The results have been compared with those obtained earlier in perchloric acid and sulphuric acid media using ferroin as catalyst. Studies have also been made to judge the relative efficiency of ferroin and CeIV ions as catalyst with single and mixed organic substrate
Application of 2D NMR Spectroscopy in Structural Elucidation of some Phenanthrene Derivatives from Indian Orchidaceae Plants
No full textDepartment of Chemistry, University College of Science, 92 Acharya Prafulla Chandra Road, Calcutta-700 009
Manuscript received 15 September 1997
The structures of the phenanthrene derivatives confusarin (2,7-dihydroxy-3,4,8-trimethoxyphenanthrene) and confusaridin (2,6- dihydroxy-3,4,7,8-tetramethoxyphenantbrene), bulbophyllantbrin (3,5-dihydroxy-2,4-dimetho-xyphenanthrene), gymnopusin (2,7 -dibydroxy-3,4,9-trimethoxyphenanthrene) and cirrhopetalanthrin (2,2 ',7, 7' -tetrahydroxy-4,4' -dimethoxy-1,1 '-biphenanthryl) [isolated from the Indian Orchidaceae plants Eria confusa, Bulbophyllum leopardium, Bulbophyllum gymnopus and Cirrhopetalum maculosum respectively] deduced mainly from 1H and 13C nmr spectral evidence have been established unequivocally from both homonuclear (1H-1H) and heteronuclear (1H-13C) 2D nmr correlation studies
Effect of some complex nutrients on improvement of bioaccumulation of lead by Rhizopus αrrhizus
No full textDepartment of Chemical Technology, University of Calcutta, 92, Acharya Prafulla Chandra Road,
Kolkata-700 009, India
E-mail : [email protected]; [email protected] Telefax : 91-33-23519755
Department of Biotechnology, Bengal Institute of Technology, On Basanti Highway, Hadia,
Kolkata-700 150, India
E-mail : [email protected]
Manuscript received 19 September 2008, accepted 19 March 2009
The present study indicated that a few complex nutrients enhanced bioaccumulation of lead by Rhizopus αrrhizus Ml from chemically defined medium containing 1 mg/L of the metal. Amongst them, yeast extract showed most prominent effect. Highly significant increment (p < 0.001) of lead accumulation of about 67% [from 147.8 µg/g (control) to 247.78 µg/g cell dry weight] was observed when the culture medium was supplemented with yeast extract at a concentration of 10 mg/ml. Specific composition of a complex nutrient was found to influence lead accumulation, when a commercial peptone preparation enriched with tryptophan showed improved bioaccumulation of lead, in comparison to other peptone. A few amino acids and water-soluble vitamins were also found to stimulate lead uptake in similar cultural conditions, although not to the extent of the complex nutrients. The present study Indicated that lead removal from aqueous systems with the use of commercially available complex nutrients as composite sources of amino acids, vitamins and other useful macromolecules for Rhizopus αrrhizus M1, would definitely provide cost-effectiveness when applied in large-scale industrial processes
Perceptions and practices of various maternal and child health services: a study among women of reproductive age group in a costal block of Ganjam District, Odisha
No full textBackground: “Healthy mothers - Healthy children” and “children’s health - tomorrows health”. Any intervention which should be planned towards the upliftment of health status of this group must start with gathering information about their present status especially in the underprivileged section. This study was conducted with an objective to assess perceptions and practices of various Maternal and Health services in the study group.Methods: An observational, cross-sectional study was conducted among women in reproductive age group residing in villages of a coastal block with a predesigned and pretested questionnaire.Results: Among the study population 54.7% women were in the 25-34 years age group, majority (46.7%) were illiterate and one-fourth of the study population age at marriage was below 18 years. Though 90.7% of study population were aware of the ongoing contraceptive practises only 37.4% of the respondents accepted some or other contraceptive methods. Fear of side effects (35.4%) found to be the chief reasons for unwillingness for adopting contraception. Majority (90.2%) responded that pregnant women need to go for ANC but only 51.9% knew correctly about minimum number of ANC. Women having adequate knowledge on ANC was found to be significantly associated with their educational status and age at marriage. Among PNC mothers 57.6% had completed the requisite no. of ANC and only 30% of respondents had completed the course of iron and folic acid tablet during their last pregnancy.Conclusions: The literacy status of the study population has to be improved which will lead to demand generation and utilization of the health and other services provided by the Government.</jats:p
Some Interesting Reactions of Gelomulides, the Natural Diterpene Lactones
No full textCentre of Advanced Studies on Natural Products, Department of Chemistry, University College of Science,
92 Acharya Prafulla Chandra Road, Calcutta-700 009
Manuscript received 27 August 1997
Some interesting chemical reactions involving the characteristic features and confirming the proposed stereostructures of gelomulides A-F (1-6), the closely related diterpene lactones from the leaves of Gelonium multiflorum (Fam. Euphorbiaceae) and some chemical correlations were carried out. Thus, 3 upon treatment with DDQ gave 4 which was also produced when 6 was treated with pyridine or methanolic NaHCO3. Zn dust/AcOH (reflux) or PPh3/I2 deepoxidized 1 and 4 to 13 and 14 respectively. PPh3/I2 converted 6 to the corresponding olefin 15 which upon refluxing with pyridine afforded 14, also obtained directly from 6 by refluxiug with Zn dust/ AcOH. NaBH4 reduction of 3 and 6 gave the corresponding tetrahydro derivatives 18 and 21; additionally, 1 and 6 gave 19 and 20 respectively. Compound 1 underwent base-catalyzed opening of the lactone and the epoxide rings, followed by ring C aromatization to give 16. Similarly, under three different acidic conditions, 4 and 6 gave the same product 17. Catalytic hydrogenation of different gelomulides caused the hydrogenolysis of the allylic epoxide bond and reduction of the Δ1,2 bond (if present) but the 3-CO group remained unaffected. The formation of the products have been rationalized in terms of the assigned stereostructures and molecular conformations of the gelomulides
Morphometric measurements of patella in population of South Bengal with literature review
No full textBackground: Morphometric analysis of patella is important for implant surgeries, medicolegal point of view. Success of total knee replacement depends on proper dimensions of the implant. Measurement varies with race and ethnicity. Several studies have been done all over India regarding measurements of patella, but there is a scarcity of data on South Bengal population.
Objective: Measurement of different parameters of patella: Thickness, height, width of articular and non- articular surfaces and correlation between them in dry bones among South Bengal population.
Materials and Methods: One hundred right and 100 left dry patellae of unknown age and sex were collected from bone libraries of different medical colleges of Kolkata as well as from Prafulla Chandra Sen Government Medical College and Hospital, Arambagh. Measurements were taken by Vernier calipers, and data analysis was done using SPSS version 16. We also classified patella according to Koyuncu's classification.
Results: We got mean and standard deviation values of height, width, thickness, width of medial and lateral articular facets, height of articular and nonarticular surface, height of articular/total height, and ratio of width of medial and lateral articular facets for right and left patellae. The measurement of medial articular facet of right and left sides of patella was 20.58 ± 2.051 and 19.98 ± 2.177, respectively. The P value of this was 0.046 which was statistically significant. We also correlated height and width with other parameters. We followed Koyuncu's classification in present study and found minimum number of type C patella 4(2%) ,19 (09.5%) samples of type A, and maximum number of type B 117(88.5%).
Conclusion: These morphometric data of patella will be helpful from medicolegal point of view as well as reconstructive surgery of knee joint
Four new stilbenoids from the orchids Coelogyne ochracea and Coelogyue cristata
No full textDepartment of Chemistry, University College of Science, 92, Acharya Prafulla Chandra Road.
Kolkata-700 009, India
E-mail : [email protected]
Manuscript received 25 March 2011, accepted 03 April 2011
The orchid Coelogyne ochracea Lindl. was earlier chemically investigated by two Indian groups of workers who reported the isolation of six new stilbenoids, viz. coelonin [2,7-dihydroxy-4-methoxy-9,10-dihydrophcnauthrcnel, ochrolidc, ochrone A, ochrone B, ochrolic acid and ochrolone, besides the known stilbenoids batahlsin-III, coclogin, coeloginin and naccidinin. Further chemical investigation of this orchid by the present investigators has resulted in the isolation of yet two new stilbenoids, designated ochracinone and ochracinanthrone, besides 3,4,5-trimethoxybenzaldyde and four known stilbenoids, other than those reported earlier viz. batatasin-III-dimethylether, flavidin oxoflavidin and flavanthrin. The orchid Coelogyne cristala Lindl. was also earlier chemically investigated in our laboratory yielding the first pair of 9,10-dihydrophenanthropyran and pyrone, coclogin and coeloginin, and latter two new phenanthrene derivatives coeloginanthrin and coeloginanthridin. Further investigation of this orchid by the present investigator afforded yet two new stilbenoids, designated coeloginone and coeloginanthrone. The structures of the four new stilbenoids ochracinone, ochracinanthrone, coeloginone and coeloginanlhrone were established as 6-hydrxy'-2, 7, 8-trimethoxy 9,1 Udihydro-5H-phenanthro[4,5-bcd]pyran-5-one, 6-hydroxy-2, 7 ,8-trimethoxy-5H-phenanthro [4,5-bcd] pyran-5-one, 2 ,6, 7, 8 trimethoxy-9,10-dihydro-5H-phenanthro[ 4,5-bcd]pyran-5-one and 2,6, 7 ,8-tetramethoxy-5H-phenanthro (4,5-bcd] pyran-5- one, respectively, from spectral and chemical evidence. Detailed 2D NMR [1-bond 1H-13C (HMQC) and 2- and 3-hond 1H-13C (HMBC) correlations] spectral studies carried out on coeloginone established unambiguous assignments all the carbon resonances of the compound and partly those of its other three congeners
AGRICULTURAL WORKERS AND BURDEN OF MORBIDITY: A COMMUNITY-BASED CROSSSECTIONAL STUDY IN A RURAL BLOCK OF WEST BENGAL
No full textObjective: Agriculture is one of the most hazardous occupations in developing and industrialized countries. Most agricultural workers in developing countries have poor housing conditions and an inadequate diet and are exposed to both general and occupational diseases. The study was undertaken to find out the prevalence of occupational morbidity and its associated risk factors among agricultural workers in a rural Block of West Bengal.
Methods: The study was conducted among agriculture workers of Habra Block-I of the state of West Bengal. Multistage random sampling method was followed to select a total of 302 individuals who were distributed among the four villages according to the Probability Proportional to Size (PPS) method.
Results: The majority of workers (58.6%) were suffering from nutritional pallor/anemia and dental carries/dental stains were 45.4%. Among other morbidities, 42% of workers were suffering from respiratory morbidity, 26.8% of workers were suffering from cardiovascular diseases, and 26.5% were suffering from hypertension. Duration of work (more than 8 h/day) was significantly associated with morbidity also other covariates such as age, sex, type of family, smoking status, and alcohol consumption had significant effects on morbidity among agriculture workers in both bivariate and multivariable linear regression.
Conclusion: This research revealed not only the high prevalence of morbidities among the study population but also the occurrence of a large population with modifiable risk factors such as alcohol consumption, smoking, high load and long duration of work, poor personal hygiene, and non-use of personal protection equipment; the latter, if taken care, will reduce the morbidities of the agriculture workers
Pharmacological studies on the anti-inflammatory and immunomodulatory role of pentoxifylline and its interaction with nitric oxide (NO) in experimental arthritis in rats
No full text
